DegronMD - Q9UBZ9(REV1)

REV1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S397Y	TCGA-19-5956	GBM	TCGA	GREKLKKMK	DEG_APCC_DBOX_1	385:393	Mutation rewiring degron network	0.2222
p.S397Y	DO13863	GBM	ICGC	GREKLKKMK	DEG_APCC_DBOX_1	385:393	Mutation rewiring degron network	0.2222
p.R396T	TCGA-B0-4811	KIRC	TCGA	GREKLKKMK	DEG_APCC_DBOX_1	385:393	Mutation rewiring degron network	0.25
p.R396T	DO17552	KIRC	ICGC	GREKLKKMK	DEG_APCC_DBOX_1	385:393	Mutation rewiring degron network	0.25
p.S397F	TCGA-B5-A3FA	UCEC	TCGA	GREKLKKMK	DEG_APCC_DBOX_1	385:393	Mutation rewiring degron network	0.2222
p.S397F	DO52402	UCEC	ICGC	GREKLKKMK	DEG_APCC_DBOX_1	385:393	Mutation rewiring degron network	0.2222
p.T394K	DO229038	LICA	ICGC	GREKLKKMK	DEG_APCC_DBOX_1	385:393	Mutation rewiring degron network	0.3056
p.M392I	DO220891	MELA	ICGC	GREKLKKMK	DEG_APCC_DBOX_1	385:393	Mutation altering degron motif	0.6507
p.N380S	SIDM00845	Burkitt's Lymphoma	GDSC	GREKLKKMK	DEG_APCC_DBOX_1	385:393	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc