DegronMD - Q9UDY4(DNAJB4)

DNAJB4

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S182Y	TCGA-ND-A4WC	UCS	TCGA	LRVSLEEIY	DEG_APCC_DBOX_1	164:172	Mutation rewiring degron network	0.0556
p.S167L	TCGA-P3-A5QF	HNSC	TCGA	LRVSLEEIY	DEG_APCC_DBOX_1	164:172	Mutation altering degron motif	0.7667
p.S167L	DO44439	HNSC	ICGC	LRVSLEEIY	DEG_APCC_DBOX_1	164:172	Mutation altering degron motif	0.7667
p.R178W	DO220823	BRCA	ICGC	LRVSLEEIY	DEG_APCC_DBOX_1	164:172	Mutation rewiring degron network	0.1667
p.I161S	SIDM00369	Esophageal Squamous Cell Carcinoma	GDSC	LRVSLEEIY	DEG_APCC_DBOX_1	164:172	Mutation rewiring degron network	0.25
p.I161S	ACH-000647	Esophageal Cancer	CCLE	LRVSLEEIY	DEG_APCC_DBOX_1	164:172	Mutation rewiring degron network	0.25
p.I161S	TE-1	oesophagus	COSMIC	LRVSLEEIY	DEG_APCC_DBOX_1	164:172	Mutation rewiring degron network	0.25
p.R178L	ACH-001645	Skin Cancer	CCLE	LRVSLEEIY	DEG_APCC_DBOX_1	164:172	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc