DegronMD - Q9UEE5(STK17A)

STK17A

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.I46V	TCGA-2K-A9WE	KIRP	TCGA	ARGLLTEIR	DEG_APCC_DBOX_1	39:47	Mutation altering degron motif	0.5965
p.I46V	DO51550	KIRP	ICGC	ARGLLTEIR	DEG_APCC_DBOX_1	39:47	Mutation altering degron motif	0.5965
p.P54S	DO228824	MALY	ICGC	ARGLLTEIR	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.1389
p.P54S	ACH-000601	Pancreatic Cancer	CCLE	ARGLLTEIR	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.1389
p.G29R	SIDM00672	Hepatocellular Carcinoma	GDSC	ARGLLTEIR	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.0556
p.G29R	SIDM00052	Esophageal Squamous Cell Carcinoma	GDSC	ARGLLTEIR	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.0556
p.G29R	SIDM01076	B-Lymphoblastic Leukemia	GDSC	ARGLLTEIR	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.0556
p.G29R	SIDM00954	Breast Carcinoma	GDSC	ARGLLTEIR	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.0556
p.G29R	SIDM00863	Burkitt's Lymphoma	GDSC	ARGLLTEIR	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.0556
p.G29R	SIDM00760	Small Cell Lung Carcinoma	GDSC	ARGLLTEIR	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.0556
p.P37T	ACH-000378	Lung Cancer	CCLE	ARGLLTEIR	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.2778
p.P37H	ACH-000378	Lung Cancer	CCLE	ARGLLTEIR	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc