DegronMD - Q9UEG4(ZNF629)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G814V	TCGA-78-7148	LUAD	TCGA	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.1944
p.G814V	DO26112	LUAD	ICGC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.1944
p.S825G	TCGA-A2-A1FX	BRCA	TCGA	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.3056
p.S825G	DO5088	BRCA	ICGC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.3056
p.G830R	TCGA-B5-A3FA	UCEC	TCGA	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.1667
p.G830R	DO52402	UCEC	ICGC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.1667
p.G830R	SIDM00122	Breast Carcinoma	GDSC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.1667
p.G830R	ACH-000288	Breast Cancer	CCLE	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.1667
p.G830R	BT-549	breast	COSMIC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.1667
p.G816V	TCGA-DQ-5629	HNSC	TCGA	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.25
p.G816V	DO15270	HNSC	ICGC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.25
p.E823K	TCGA-EY-A215	UCEC	TCGA	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation altering degron motif	0.591
p.E823K	DO42665	UCEC	ICGC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation altering degron motif	0.591
p.G830E	TCGA-MA-AA42	CESC	TCGA	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.1667
p.G830E	DO219724	CESC	ICGC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.1667
p.N832T	DO7511	CLLE	ICGC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.1111
p.S826R	DO229035	LICA	ICGC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.2778
p.H827L	SIDM00690	Head and Neck Carcinoma	GDSC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.25
p.H827L	SIDM00529	Breast Carcinoma	GDSC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.25
p.H827L	SIDM00052	Esophageal Squamous Cell Carcinoma	GDSC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.25
p.H827L	SIDM00971	Breast Carcinoma	GDSC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.25
p.H827L	SIDM00844	Burkitt's Lymphoma	GDSC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.25
p.H827L	SIDM00793	Burkitt's Lymphoma	GDSC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.25
p.H827L	SIDM01133	Other Solid Cancers	GDSC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.25
p.H827L	SIDM00068	Colorectal Carcinoma	GDSC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.25
p.H827L	SIDM01140	Ovarian Carcinoma	GDSC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.25
p.H827L	SIDM00628	Breast Carcinoma	GDSC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.25
p.P833L	SIDM00837	Colorectal Carcinoma	GDSC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.0833
p.P833L	ACH-000958	Colon/Colorectal Cancer	CCLE	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.0833
p.P833L	SW48	large intestine	COSMIC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.0833
p.Q812H	SIDM00153	T-Lymphoblastic Leukemia	GDSC	PTPTES	DEG_SCF_FBW7_1	819:824	Mutation rewiring degron network	0.1389

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ZNF629

UniProt ID: Q9UEG4

Entrez ID: 23361

Protein name: Zinc finger protein 629 (Zinc finger protein 65)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for ZNF629 in