DegronMD - Q9UGC7(MTRF1L)

MTRF1L

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R213H	TCGA-BR-8487	STAD	TCGA	VHTST	DEG_SPOP_SBC_1	214:218	Mutation rewiring degron network	0.3056
p.R213H	DO234462	ESAD	ICGC	VHTST	DEG_SPOP_SBC_1	214:218	Mutation rewiring degron network	0.3056
p.R213H	DO47867	STAD	ICGC	VHTST	DEG_SPOP_SBC_1	214:218	Mutation rewiring degron network	0.3056
p.R213H	ACH-000533	Rhabdoid	CCLE	VHTST	DEG_SPOP_SBC_1	214:218	Mutation rewiring degron network	0.3056
p.T228A	TCGA-CG-5721	STAD	TCGA	VHTST	DEG_SPOP_SBC_1	214:218	Mutation blocking phosphorylation signal	0.5
p.T228A	DO38192	STAD	ICGC	VHTST	DEG_SPOP_SBC_1	214:218	Mutation blocking phosphorylation signal	0.5
p.K207N	TCGA-P4-A5EA	KIRP	TCGA	VHTST	DEG_SPOP_SBC_1	214:218	Mutation substituting flanking lysine	0.25
p.K207N	DO48582	KIRP	ICGC	VHTST	DEG_SPOP_SBC_1	214:218	Mutation substituting flanking lysine	0.25
p.V214I	DO229003	COCA	ICGC	VHTST	DEG_SPOP_SBC_1	214:218	Mutation altering degron motif	0.7076
p.V214I	DO229005	COCA	ICGC	VHTST	DEG_SPOP_SBC_1	214:218	Mutation altering degron motif	0.7076
p.V214I	DO228941	LICA	ICGC	VHTST	DEG_SPOP_SBC_1	214:218	Mutation altering degron motif	0.7076
p.V214I	DO231049	LUSC	ICGC	VHTST	DEG_SPOP_SBC_1	214:218	Mutation altering degron motif	0.7076
p.P225T	DO229026	LICA	ICGC	VHTST	DEG_SPOP_SBC_1	214:218	Mutation rewiring degron network	0.1389
p.V205M	DO50712	ORCA	ICGC	VHTST	DEG_SPOP_SBC_1	214:218	Mutation rewiring degron network	0.0833
p.P225H	ACH-001369	Ovarian Cancer	CCLE	VHTST	DEG_SPOP_SBC_1	214:218	Mutation rewiring degron network	0.1389

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc