DegronMD - Q9UGM5(FETUB)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q335H	TCGA-17-Z045	LUAD	TCGA	FPVHLD	LIG_APCC_ABBA_1	324:329	Mutation rewiring degron network	0.1667
p.Q335H	TCGA-EE-A3AA	SKCM	TCGA	FPVHLD	LIG_APCC_ABBA_1	324:329	Mutation rewiring degron network	0.1667
p.E337K	TCGA-DK-A3IT	BLCA	TCGA	FPVHLD	LIG_APCC_ABBA_1	324:329	Mutation rewiring degron network	0.1111
p.E337K	TCGA-FR-A8YC	SKCM	TCGA	FPVHLD	LIG_APCC_ABBA_1	324:329	Mutation rewiring degron network	0.1111
p.E337K	TCGA-UY-A9PB	BLCA	TCGA	FPVHLD	LIG_APCC_ABBA_1	324:329	Mutation rewiring degron network	0.1111
p.P320T	TCGA-DK-AA77	BLCA	TCGA	FPVHLD	LIG_APCC_ABBA_1	324:329	Mutation rewiring degron network	0.2222
p.G336E	TCGA-EE-A29E	SKCM	TCGA	FPVHLD	LIG_APCC_ABBA_1	324:329	Mutation rewiring degron network	0.1389
p.G336E	TCGA-EE-A2M5	SKCM	TCGA	FPVHLD	LIG_APCC_ABBA_1	324:329	Mutation rewiring degron network	0.1389
p.G336E	SIDM01029	Esophageal Squamous Cell Carcinoma	GDSC	FPVHLD	LIG_APCC_ABBA_1	324:329	Mutation rewiring degron network	0.1389
p.G336E	KYSE-270	oesophagus	COSMIC	FPVHLD	LIG_APCC_ABBA_1	324:329	Mutation rewiring degron network	0.1389
p.G336R	TCGA-EE-A2GR	SKCM	TCGA	FPVHLD	LIG_APCC_ABBA_1	324:329	Mutation rewiring degron network	0.1389
p.G336R	TCGA-EE-A2M5	SKCM	TCGA	FPVHLD	LIG_APCC_ABBA_1	324:329	Mutation rewiring degron network	0.1389
p.N314H	TCGA-EO-A3B0	UCEC	TCGA	FPVHLD	LIG_APCC_ABBA_1	324:329	Mutation rewiring degron network	0.0556
p.A323T	SIDM01608	Endometrial Carcinoma	GDSC	FPVHLD	LIG_APCC_ABBA_1	324:329	Mutation rewiring degron network	0.3056
p.P316Q	ACH-000749	Lung Cancer	CCLE	FPVHLD	LIG_APCC_ABBA_1	324:329	Mutation rewiring degron network	0.1111
p.P316Q	DMS-273	lung	COSMIC	FPVHLD	LIG_APCC_ABBA_1	324:329	Mutation rewiring degron network	0.1111
p.T328I	GEO	large intestine	COSMIC	FPVHLD	LIG_APCC_ABBA_1	324:329	Mutation altering degron motif	0.7078
p.P334S	SNU-C2B	large intestine	COSMIC	FPVHLD	LIG_APCC_ABBA_1	324:329	Mutation rewiring degron network	0.1944

Kaplan plot for FETUB in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

FETUB

UniProt ID: Q9UGM5

Entrez ID: 26998

Protein name: Fetuin-B (16G2) (Fetuin-like protein IRL685) (Gugu)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for FETUB in