SLC23A1
UniProt ID: Q9UHI7
Entrez ID: 9963
Protein name: Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (hSVCT1) (Yolk sac permease-like molecule 3)
External links: UniprotKB HGNC RefSeq COSMIC
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FUNCTION: Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate. {ECO:0000269|PubMed:10556483, ECO:0000269|PubMed:10556521, ECO:0000269|PubMed:10631088}.; FUNCTION: [Isoform 2]: Inactive transporter. {ECO:0000269|PubMed:10556483...
FUNCTION: Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate. {ECO:0000269|PubMed:10556483, ECO:0000269|PubMed:10556521, ECO:0000269|PubMed:10631088}.; FUNCTION: [Isoform 2]: Inactive transporter. {ECO:0000269|PubMed:10556483}.
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GO - Biological processes (BP):
brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid metabolic process [GO:0019852]; L-ascorbic acid transmembrane transport [GO:0015882]; lung development [GO:0030324]; nucleobase transport [GO:0015851]; response to toxic substance [GO:0009636]; sodium ion tr...
brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid metabolic process [GO:0019852]; L-ascorbic acid transmembrane transport [GO:0015882]; lung development [GO:0030324]; nucleobase transport [GO:0015851]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814]; transepithelial L-ascorbic acid transport [GO:0070904]
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GO - Molecular function (MF):
dehydroascorbic acid transmembrane transporter activity [GO:0033300]; L-ascorbate:sodium symporter activity [GO:0008520]; L-ascorbic acid transmembrane transporter activity [GO:0015229]; nucleobase transmembrane transporter activity [GO:0015205]; sodium ion transmembrane transporter activity [GO:001...
dehydroascorbic acid transmembrane transporter activity [GO:0033300]; L-ascorbate:sodium symporter activity [GO:0008520]; L-ascorbic acid transmembrane transporter activity [GO:0015229]; nucleobase transmembrane transporter activity [GO:0015205]; sodium ion transmembrane transporter activity [GO:0015081]
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GO - Cellular component (CC):
apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; brush border [GO:0005903]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; intracellular organelle [GO:0043229]; plasma membrane [GO:0005886]...
apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; brush border [GO:0005903]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; intracellular organelle [GO:0043229]; plasma membrane [GO:0005886]
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SLC23A1
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Kaplan plot for SLC23A1 in
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*NOTE: the Kaplan plots were collected from OncoLnc