DegronMD - Q9UHI8(ADAMTS1)

ADAMTS1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R75H	TCGA-UZ-A9PL	KIRP	TCGA	SEEDEELVVPEL	DEG_COP1_1	54:65	Mutation rewiring degron network	0.0556
p.R75H	DO219701	KIRP	ICGC	SEEDEELVVPEL	DEG_COP1_1	54:65	Mutation rewiring degron network	0.0556
p.T73S	DO19733	KIRC	ICGC	SEEDEELVVPEL	DEG_COP1_1	54:65	Mutation rewiring degron network	0.1111
p.E55K	DO228424	MALY	ICGC	SEEDEELVVPEL	DEG_COP1_1	54:65	Mutation altering degron motif	0.7022
p.R52H	DO38404	STAD	ICGC	SEEDEELVVPEL	DEG_COP1_1	54:65	Mutation rewiring degron network	0.2778
p.P69R	DO229272	THCA	ICGC	SEEDEELVVPEL	DEG_COP1_1	54:65	Mutation rewiring degron network	0.2222
p.A68T	DO229208	THCA	ICGC	SEEDEELVVPEL	DEG_COP1_1	54:65	Mutation rewiring degron network	0.25
p.A68V	SIDM01003	T-Lymphoblastic Leukemia	GDSC	SEEDEELVVPEL	DEG_COP1_1	54:65	Mutation rewiring degron network	0.25
p.R75G	ACH-000463	Lung Cancer	CCLE	SEEDEELVVPEL	DEG_COP1_1	54:65	Mutation rewiring degron network	0.0556
p.E64Q	ACH-000831	Endometrial/Uterine Cancer	CCLE	SEEDEELVVPEL	DEG_COP1_1	54:65	Mutation altering degron motif	0.6744

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*NOTE: the Kaplan plots were collected from OncoLnc