DegronMD - Q9UHL0(DDX25)

DDX25

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.N24D	TCGA-AD-6964	COAD	TCGA	PRKNLWGIK	DEG_APCC_DBOX_1	28:36	Mutation rewiring degron network	0.2222
p.N24D	DO8360	COAD	ICGC	PRKNLWGIK	DEG_APCC_DBOX_1	28:36	Mutation rewiring degron network	0.2222
p.R41Q	TCGA-D1-A167	UCEC	TCGA	PRKNLWGIK	DEG_APCC_DBOX_1	28:36	Mutation rewiring degron network	0.1944
p.R41Q	DO40978	UCEC	ICGC	PRKNLWGIK	DEG_APCC_DBOX_1	28:36	Mutation rewiring degron network	0.1944
p.V40D	DO9042	COAD	ICGC	PRKNLWGIK	DEG_APCC_DBOX_1	28:36	Mutation rewiring degron network	0.2222
p.G45A	DO224761	COCA	ICGC	PRKNLWGIK	DEG_APCC_DBOX_1	28:36	Mutation rewiring degron network	0.0833
p.K36N	DO229027	LICA	ICGC	PRKNLWGIK	DEG_APCC_DBOX_1	28:36	Mutation altering degron motif	0.5806
p.S46F	SIDM00584	Osteosarcoma	GDSC	PRKNLWGIK	DEG_APCC_DBOX_1	28:36	Mutation rewiring degron network	0.0556
p.S37R	SIDM00653	Small Cell Lung Carcinoma	GDSC	PRKNLWGIK	DEG_APCC_DBOX_1	28:36	Mutation rewiring degron network	0.3056
p.S37R	ACH-000514	Lung Cancer	CCLE	PRKNLWGIK	DEG_APCC_DBOX_1	28:36	Mutation rewiring degron network	0.3056
p.S37R	NCI-H1092	lung	COSMIC	PRKNLWGIK	DEG_APCC_DBOX_1	28:36	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc