DegronMD - Q9UIB8(CD84)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P335H	TCGA-AX-A06F	UCEC	TCGA	PGTSS	DEG_SPOP_SBC_1	336:340	Mutation rewiring degron network	0.3056
p.P335H	TCGA-D1-A17Q	UCEC	TCGA	PGTSS	DEG_SPOP_SBC_1	336:340	Mutation rewiring degron network	0.3056
p.T338N	TCGA-D1-A17Q	UCEC	TCGA	PGTSS	DEG_SPOP_SBC_1	336:340	Mutation altering degron motif	0.7055
p.K327N	TCGA-D7-6818	STAD	TCGA	PGTSS	DEG_SPOP_SBC_1	336:340	Mutation substituting flanking lysine	0.1944
p.E342K	TCGA-VS-A958	CESC	TCGA	PGTSS	DEG_SPOP_SBC_1	336:340	Mutation rewiring degron network	0.2778
p.I337T	DO222651	BTCA	ICGC	PGTSS	DEG_SPOP_SBC_1	336:340	Mutation altering degron motif	0.7078
p.E336K	DO51639	CESC	ICGC	PGTSS	DEG_SPOP_SBC_1	336:340	Mutation altering degron motif	0.7022
p.V338L	DO233697	GACA	ICGC	PGTSS	DEG_SPOP_SBC_1	336:340	Mutation altering degron motif	0.6765
p.P329T	DO228976	LICA	ICGC	PGTSS	DEG_SPOP_SBC_1	336:340	Mutation rewiring degron network	0.1389
p.P329T	DO229041	LICA	ICGC	PGTSS	DEG_SPOP_SBC_1	336:340	Mutation rewiring degron network	0.1389
p.S334R	DO229041	LICA	ICGC	PGTSS	DEG_SPOP_SBC_1	336:340	Mutation rewiring degron network	0.2778
p.Y335C	DO46763	PAEN	ICGC	PGTSS	DEG_SPOP_SBC_1	336:340	Mutation rewiring degron network	0.3056
p.P329H	DO41752	UCEC	ICGC	PGTSS	DEG_SPOP_SBC_1	336:340	Mutation rewiring degron network	0.1389
p.P329H	DO41903	UCEC	ICGC	PGTSS	DEG_SPOP_SBC_1	336:340	Mutation rewiring degron network	0.1389
p.T332N	DO41903	UCEC	ICGC	PGTSS	DEG_SPOP_SBC_1	336:340	Mutation rewiring degron network	0.2222
p.Q331H	SIDM00384	B-Cell Non-Hodgkin's Lymphoma	GDSC	PGTSS	DEG_SPOP_SBC_1	336:340	Mutation rewiring degron network	0.1944
p.Q331H	ACH-001642	Lymphoma	CCLE	PGTSS	DEG_SPOP_SBC_1	336:340	Mutation rewiring degron network	0.1944
p.Q331H	SCC-3	haematopoietic and lymphoid tissue	COSMIC	PGTSS	DEG_SPOP_SBC_1	336:340	Mutation rewiring degron network	0.1944

Kaplan plot for CD84 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CD84

UniProt ID: Q9UIB8

Entrez ID: 8832

Protein name: SLAM family member 5 (Cell surface antigen MAX.3) (Hly9-beta) (Leukocyte differentiation antigen CD84) (Signaling lymphocytic activation molecule 5) (CD antigen CD84)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for CD84 in