DegronMD - Q9UIG8(SLCO3A1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.M297I	TCGA-04-1652	OV	TCGA	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation rewiring degron network	0.25
p.M297I	DO29248	OV	ICGC	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation rewiring degron network	0.25
p.F283C	TCGA-44-7671	LUAD	TCGA	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation rewiring degron network	0.1667
p.F283C	DO25252	LUAD	ICGC	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation rewiring degron network	0.1667
p.A302P	TCGA-85-7698	LUSC	TCGA	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation rewiring degron network	0.1111
p.A302P	DO27723	LUSC	ICGC	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation rewiring degron network	0.1111
p.P286S	TCGA-DU-6392	LGG	TCGA	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation rewiring degron network	0.25
p.P286S	DO22237	LGG	ICGC	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation rewiring degron network	0.25
p.S279C	TCGA-FW-A3R5	SKCM	TCGA	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation rewiring degron network	0.0556
p.S279C	DO37406	SKCM	ICGC	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation rewiring degron network	0.0556
p.L280F	TCGA-FW-A3R5	SKCM	TCGA	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation rewiring degron network	0.0833
p.L280F	DO37406	SKCM	ICGC	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation rewiring degron network	0.0833
p.A296T	TCGA-G4-6586	COAD	TCGA	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation rewiring degron network	0.2778
p.A296T	DO9698	COAD	ICGC	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation rewiring degron network	0.2778
p.A296T	SIDM00853	Other Sarcomas	GDSC	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation rewiring degron network	0.2778
p.A296T	GCT	soft tissue	COSMIC	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation rewiring degron network	0.2778
p.E294D	DO229010	COCA	ICGC	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation altering degron motif	0.5647
p.E294D	DO229013	COCA	ICGC	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation altering degron motif	0.5647
p.E294D	DO229016	COCA	ICGC	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation altering degron motif	0.5647
p.E294D	DO229003	COCA	ICGC	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation altering degron motif	0.5647
p.E294D	DO229005	COCA	ICGC	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation altering degron motif	0.5647
p.P291T	DO219966	SARC	ICGC	LPPHSE	LIG_APCC_ABBA_1	289:294	Mutation altering degron motif	0.7031

Kaplan plot for SLCO3A1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

SLCO3A1

UniProt ID: Q9UIG8

Entrez ID: 28232

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for SLCO3A1 in