DegronMD - Q9UJL9(ZFP69B)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S59I	TCGA-26-6173	GBM	TCGA	SRVTLGSLT	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.623
p.S59I	DO13827	GBM	ICGC	SRVTLGSLT	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.623
p.G54S	TCGA-AJ-A3EK	UCEC	TCGA	SRVTLGSLT	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.1944
p.G54S	DO41584	UCEC	ICGC	SRVTLGSLT	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.1944
p.E55K	DO225208	BRCA	ICGC	SRVTLGSLT	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.2222
p.I51V	DO8938	COAD	ICGC	SRVTLGSLT	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.1111
p.S56R	DO50450	ESAD	ICGC	SRVTLGSLT	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.25
p.S56R	DO50343	ESAD	ICGC	SRVTLGSLT	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.25
p.G58E	DO233150	GACA	ICGC	SRVTLGSLT	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.3056
p.G68V	DO228938	LICA	ICGC	SRVTLGSLT	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.3056
p.A49S	DO229006	LICA	ICGC	SRVTLGSLT	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.0556
p.F74Y	DO51276	SKCM	ICGC	SRVTLGSLT	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.1389
p.M70T	DO38288	STAD	ICGC	SRVTLGSLT	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.25
p.E58Q	SIDM00747	Non-Small Cell Lung Carcinoma	GDSC	SRVTLGSLT	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.3056
p.E58Q	ACH-000744	Lung Cancer	CCLE	SRVTLGSLT	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.3056
p.E58Q	NCI-H1623	lung	COSMIC	SRVTLGSLT	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.3056

Kaplan plot for ZFP69B in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ZFP69B

UniProt ID: Q9UJL9

Entrez ID: 65243

Protein name: Zinc finger protein 69 homolog B (Zinc finger protein 643)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for ZFP69B in