DegronMD - Q9UJW9(SERTAD3)

SERTAD3

UniProt ID: Q9UJW9

Entrez ID: 29946

Protein name: SERTA domain-containing protein 3 (Replication protein-binding trans-activator) (RPA-binding trans-activator)

External links: UniprotKB HGNC RefSeq COSMIC

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GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P73A	TCGA-90-A4ED	LUSC	TCGA	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation altering degron motif	0.7503
p.P73A	DO45482	LUSC	ICGC	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation altering degron motif	0.7503
p.E87D	TCGA-EE-A2M8	SKCM	TCGA	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation rewiring degron network	0.25
p.E87D	DO38075	SKCM	ICGC	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation rewiring degron network	0.25
p.R70C	TCGA-IH-A3EA	SKCM	TCGA	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation rewiring degron network	0.3056
p.R70C	DO37667	SKCM	ICGC	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation rewiring degron network	0.3056
p.L71Q	TCGA-LG-A6GG	LIHC	TCGA	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation altering degron motif	0.7765
p.L71Q	DO49699	LIHC	ICGC	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation altering degron motif	0.7765
p.P81L	TCGA-OD-A75X	SKCM	TCGA	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation altering degron motif	0.6471
p.P81L	DO48601	SKCM	ICGC	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation altering degron motif	0.6471
p.L69I	DO228974	LICA	ICGC	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation rewiring degron network	0.2778
p.S90C	SIDM00557	Neuroblastoma	GDSC	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation rewiring degron network	0.1667
p.S90C	ACH-000345	Neuroblastoma	CCLE	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation rewiring degron network	0.1667
p.S90C	KP-N-RT-BM-1	autonomic ganglia	COSMIC	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation rewiring degron network	0.1667
p.A72T	SIDM01146	Gastric Carcinoma	GDSC	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation altering degron motif	0.7139
p.A72T	ACH-000932	Gastric Cancer	CCLE	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation altering degron motif	0.7139
p.A72T	NCI-SNU-1	stomach	COSMIC	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation altering degron motif	0.7139
p.A74T	SIDM00220	Ovarian Carcinoma	GDSC	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation altering degron motif	0.6028
p.A74T	ACH-000962	Ovarian Cancer	CCLE	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation altering degron motif	0.6028
p.A74T	OC-314	ovary	COSMIC	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation altering degron motif	0.6028
p.T61P	SUP-HD1	haematopoietic and lymphoid tissue	COSMIC	LAPAPALPPEPLFL	DEG_ODPH_VHL_1	71:84	Mutation rewiring degron network	0.0556

Kaplan plot for SERTAD3 in

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*NOTE: the Kaplan plots were collected from OncoLnc