DegronMD - Q9UJY1(HSPB8)

HSPB8

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P41L	TCGA-33-4532	LUSC	TCGA	MDPFPD	LIG_APCC_ABBA_1	37:42	Mutation altering degron motif	0.6471
p.P41L	DO26626	LUSC	ICGC	MDPFPD	LIG_APCC_ABBA_1	37:42	Mutation altering degron motif	0.6471
p.R29H	TCGA-AG-3727	READ	TCGA	MDPFPD	LIG_APCC_ABBA_1	37:42	Mutation rewiring degron network	0.1111
p.R29H	TCGA-EO-A22R	UCEC	TCGA	MDPFPD	LIG_APCC_ABBA_1	37:42	Mutation rewiring degron network	0.1111
p.R29H	DO37138	READ	ICGC	MDPFPD	LIG_APCC_ABBA_1	37:42	Mutation rewiring degron network	0.1111
p.R29H	DO42713	UCEC	ICGC	MDPFPD	LIG_APCC_ABBA_1	37:42	Mutation rewiring degron network	0.1111
p.A46T	TCGA-AX-A2HD	UCEC	TCGA	MDPFPD	LIG_APCC_ABBA_1	37:42	Mutation rewiring degron network	0.2222
p.A46T	DO42608	UCEC	ICGC	MDPFPD	LIG_APCC_ABBA_1	37:42	Mutation rewiring degron network	0.2222
p.D38E	DO230931	LUSC	ICGC	MDPFPD	LIG_APCC_ABBA_1	37:42	Mutation altering degron motif	0.5647
p.D38E	DO224548	LUSC	ICGC	MDPFPD	LIG_APCC_ABBA_1	37:42	Mutation altering degron motif	0.5647
p.D43N	SIDM00251	Gastric Carcinoma	GDSC	MDPFPD	LIG_APCC_ABBA_1	37:42	Mutation rewiring degron network	0.3056
p.D43N	ACH-000949	Gastric Cancer	CCLE	MDPFPD	LIG_APCC_ABBA_1	37:42	Mutation rewiring degron network	0.3056
p.D43N	TGBC11TKB	stomach	COSMIC	MDPFPD	LIG_APCC_ABBA_1	37:42	Mutation rewiring degron network	0.3056
p.D38N	ACH-002027	Endometrial/Uterine Cancer	CCLE	MDPFPD	LIG_APCC_ABBA_1	37:42	Mutation altering degron motif	0.5821

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*NOTE: the Kaplan plots were collected from OncoLnc