DegronMD - Q9UKA2(FBXL4)

FBXL4

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L175F	TCGA-D9-A148	SKCM	TCGA	NPYSPNP	CBL_PTK	160:166	Mutation rewiring degron network	0.0833
p.L175F	DO222711	ESCA	ICGC	NPYSPNP	CBL_PTK	160:166	Mutation rewiring degron network	0.0833
p.L175F	DO37971	SKCM	ICGC	NPYSPNP	CBL_PTK	160:166	Mutation rewiring degron network	0.0833
p.I152S	TCGA-DD-A39Z	LIHC	TCGA	NPYSPNP	CBL_PTK	160:166	Mutation rewiring degron network	0.1111
p.I152S	DO44954	LIHC	ICGC	NPYSPNP	CBL_PTK	160:166	Mutation rewiring degron network	0.1111
p.W172L	TCGA-E8-A2EA	THCA	TCGA	NPYSPNP	CBL_PTK	160:166	Mutation rewiring degron network	0.1667
p.W172L	DO38926	THCA	ICGC	NPYSPNP	CBL_PTK	160:166	Mutation rewiring degron network	0.1667
p.P166S	TCGA-EE-A17X	SKCM	TCGA	NPYSPNP	CBL_PTK	160:166	Mutation altering degron motif	0.6752
p.P166S	DO37931	SKCM	ICGC	NPYSPNP	CBL_PTK	160:166	Mutation altering degron motif	0.6752
p.Y162C	DO233652	GACA	ICGC	NPYSPNP	CBL_PTK	160:166	Mutation altering degron motif	0.7087
p.P164Q	DO228971	LICA	ICGC	NPYSPNP	CBL_PTK	160:166	Mutation altering degron motif	0.5924
p.A156T	DO27923	ORCA	ICGC	NPYSPNP	CBL_PTK	160:166	Mutation rewiring degron network	0.2222
p.N165H	ACH-001147	Lymphoma	CCLE	NPYSPNP	CBL_PTK	160:166	Mutation altering degron motif	0.6312

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*NOTE: the Kaplan plots were collected from OncoLnc