DegronMD - Q9UKJ1(PILRA)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E143K	TCGA-AA-3864	COAD	TCGA	AVTTT	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.0833
p.E143K	DO8490	COAD	ICGC	AVTTT	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.0833
p.T154M	TCGA-BT-A20N	BLCA	TCGA	AVTTT	DEG_SPOP_SBC_1	152:156	Mutation altering degron motif	0.7423
p.T154M	DO550	BLCA	ICGC	AVTTT	DEG_SPOP_SBC_1	152:156	Mutation altering degron motif	0.7423
p.P284S	TCGA-D7-5577	STAD	TCGA	ALSSS	DEG_SPOP_SBC_1	273:277	Mutation rewiring degron network	0.1389
p.V268I	TCGA-GV-A40G	BLCA	TCGA	ALSSS	DEG_SPOP_SBC_1	273:277	Mutation rewiring degron network	0.1944
p.R163I	DO228952	LICA	ICGC	AVTTT	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.1389
p.G144V	DO228978	LICA	ICGC	AVTTT	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.1111
p.S160I	DO229035	LICA	ICGC	AVTTT	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.2222
p.G152E	DO50303	SKCM	ICGC	AVTTT	DEG_SPOP_SBC_1	152:156	Mutation altering degron motif	0.7199
p.R159G	DO51259	SKCM	ICGC	AVTTT	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.25
p.A273V	SIDM00948	Burkitt's Lymphoma	GDSC	ALSSS	DEG_SPOP_SBC_1	273:277	Mutation altering degron motif	0.5825
p.A273V	ACH-002232	Lymphoma	CCLE	ALSSS	DEG_SPOP_SBC_1	273:277	Mutation altering degron motif	0.5825
p.A273V	DG-75	haematopoietic and lymphoid tissue	COSMIC	ALSSS	DEG_SPOP_SBC_1	273:277	Mutation altering degron motif	0.5825
p.Q158H	ACH-002834	Bone Cancer	CCLE	AVTTT	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.2778
p.G152D	YH-13	central nervous system	COSMIC	AVTTT	DEG_SPOP_SBC_1	152:156	Mutation altering degron motif	0.7198
p.E164K	SK-MEL-5	skin	COSMIC	AVTTT	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.1111

Kaplan plot for PILRA in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

PILRA

UniProt ID: Q9UKJ1

Entrez ID: 29992

Protein name: Paired immunoglobulin-like type 2 receptor alpha (Cell surface receptor FDF03) (Inhibitory receptor PILR-alpha)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for PILRA in