DegronMD - Q9UKL0(RCOR1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R126H	TCGA-HU-8602	STAD	TCGA	ERDNLGMLV	DEG_APCC_DBOX_1	129:137	Mutation rewiring degron network	0.25
p.R126H	DO233641	GACA	ICGC	ERDNLGMLV	DEG_APCC_DBOX_1	129:137	Mutation rewiring degron network	0.25
p.R126H	DO228138	PBCA	ICGC	ERDNLGMLV	DEG_APCC_DBOX_1	129:137	Mutation rewiring degron network	0.25
p.R126H	DO47829	STAD	ICGC	ERDNLGMLV	DEG_APCC_DBOX_1	129:137	Mutation rewiring degron network	0.25
p.R130W	DO10806	EOPC	ICGC	ERDNLGMLV	DEG_APCC_DBOX_1	129:137	Mutation altering degron motif	0.8634
p.W138L	DO228978	LICA	ICGC	ERDNLGMLV	DEG_APCC_DBOX_1	129:137	Mutation rewiring degron network	0.3056
p.G134V	DO229045	LICA	ICGC	ERDNLGMLV	DEG_APCC_DBOX_1	129:137	Mutation altering degron motif	0.6421
p.D119Y	DO229009	LICA	ICGC	ERDNLGMLV	DEG_APCC_DBOX_1	129:137	Mutation rewiring degron network	0.0556
p.Q142E	DO27879	ORCA	ICGC	ERDNLGMLV	DEG_APCC_DBOX_1	129:137	Mutation rewiring degron network	0.1944
p.L133F	DO229456	SKCA	ICGC	ERDNLGMLV	DEG_APCC_DBOX_1	129:137	Mutation altering degron motif	0.6981
p.R125I	SIDM01611	Endometrial Carcinoma	GDSC	ERDNLGMLV	DEG_APCC_DBOX_1	129:137	Mutation rewiring degron network	0.2222
p.R125I	ACH-000996	Endometrial/Uterine Cancer	CCLE	ERDNLGMLV	DEG_APCC_DBOX_1	129:137	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons