DegronMD - Q9UKY7(CDV3)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V147I	TCGA-AJ-A3EK	UCEC	TCGA	APVIV	DEG_Kelch_actinfilin_1	152:156	Mutation rewiring degron network	0.1944
p.V147I	DO41584	UCEC	ICGC	APVIV	DEG_Kelch_actinfilin_1	152:156	Mutation rewiring degron network	0.1944
p.P153S	DO52438	COCA	ICGC	APVIV	DEG_Kelch_actinfilin_1	152:156	Mutation altering degron motif	0.6752
p.P153S	SIDM00434	Plasma Cell Myeloma	GDSC	APVIV	DEG_Kelch_actinfilin_1	152:156	Mutation altering degron motif	0.6752
p.P153S	SIDM00231	Kidney Carcinoma	GDSC	APVIV	DEG_Kelch_actinfilin_1	152:156	Mutation altering degron motif	0.6752
p.P153S	SIDM00543	Melanoma	GDSC	APVIV	DEG_Kelch_actinfilin_1	152:156	Mutation altering degron motif	0.6752
p.P153S	SIDM00161	Biliary Tract Carcinoma	GDSC	APVIV	DEG_Kelch_actinfilin_1	152:156	Mutation altering degron motif	0.6752
p.A149S	DO50737	LICA	ICGC	APVIV	DEG_Kelch_actinfilin_1	152:156	Mutation rewiring degron network	0.25
p.P151H	DO229253	THCA	ICGC	APVIV	DEG_Kelch_actinfilin_1	152:156	Mutation rewiring degron network	0.3056
p.P151S	SIDM00516	Melanoma	GDSC	APVIV	DEG_Kelch_actinfilin_1	152:156	Mutation rewiring degron network	0.3056
p.P151S	MZ7-mel	skin	COSMIC	APVIV	DEG_Kelch_actinfilin_1	152:156	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons