DegronMD - Q9UL45(BLOC1S6)

BLOC1S6

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L20M	TCGA-AP-A1DK	UCEC	TCGA	PTPGLS	DEG_SCF_FBW7_1	25:30	Mutation rewiring degron network	0.1944
p.L20M	DO42033	UCEC	ICGC	PTPGLS	DEG_SCF_FBW7_1	25:30	Mutation rewiring degron network	0.1944
p.E40K	TCGA-BR-A4QL	STAD	TCGA	PTPGLS	DEG_SCF_FBW7_1	25:30	Mutation rewiring degron network	0.0556
p.I39V	TCGA-D1-A17Q	UCEC	TCGA	PTPGLS	DEG_SCF_FBW7_1	25:30	Mutation rewiring degron network	0.0833
p.D35N	TCGA-FD-A3SO	BLCA	TCGA	PTPGLS	DEG_SCF_FBW7_1	25:30	Mutation rewiring degron network	0.1944
p.D35N	DO569	BLCA	ICGC	PTPGLS	DEG_SCF_FBW7_1	25:30	Mutation rewiring degron network	0.1944
p.L38S	DO219738	CESC	ICGC	PTPGLS	DEG_SCF_FBW7_1	25:30	Mutation rewiring degron network	0.1111
p.C19F	DO228978	LICA	ICGC	PTPGLS	DEG_SCF_FBW7_1	25:30	Mutation rewiring degron network	0.1667
p.S30R	DO228418	MALY	ICGC	PTPGLS	DEG_SCF_FBW7_1	25:30	Mutation altering degron motif	0.7427
p.C19S	DO52126	PAEN	ICGC	PTPGLS	DEG_SCF_FBW7_1	25:30	Mutation rewiring degron network	0.1667
p.V39A	DO41871	UCEC	ICGC	PTPGLS	DEG_SCF_FBW7_1	25:30	Mutation rewiring degron network	0.0833
p.G28S	SIDM01314	Colorectal Carcinoma	GDSC	PTPGLS	DEG_SCF_FBW7_1	25:30	Mutation altering degron motif	0.5882
p.R22K	ACH-000541	Myeloma	CCLE	PTPGLS	DEG_SCF_FBW7_1	25:30	Mutation rewiring degron network	0.25
p.E31K	TT	thyroid	COSMIC	PTPGLS	DEG_SCF_FBW7_1	25:30	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc