DegronMD - Q9ULH1(ASAP1)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D860Y	TCGA-44-7667	LUAD	TCGA	PSSSS	DEG_SPOP_SBC_1	863:867	Mutation rewiring degron network	0.25
p.D860Y	DO23830	LUAD	ICGC	PSSSS	DEG_SPOP_SBC_1	863:867	Mutation rewiring degron network	0.25
p.W857C	TCGA-69-A59K	LUAD	TCGA	PSSSS	DEG_SPOP_SBC_1	863:867	Mutation rewiring degron network	0.1667
p.W857C	DO45335	LUAD	ICGC	PSSSS	DEG_SPOP_SBC_1	863:867	Mutation rewiring degron network	0.1667
p.G853C	TCGA-75-5126	LUAD	TCGA	PSSSS	DEG_SPOP_SBC_1	863:867	Mutation rewiring degron network	0.0556
p.G853C	DO23711	LUAD	ICGC	PSSSS	DEG_SPOP_SBC_1	863:867	Mutation rewiring degron network	0.0556
p.E789K	TCGA-AC-A23H	BRCA	TCGA	VSTST	DEG_SPOP_SBC_1	776:780	Mutation rewiring degron network	0.0833
p.E789K	DO2401	BRCA	ICGC	VSTST	DEG_SPOP_SBC_1	776:780	Mutation rewiring degron network	0.0833
p.A854T	TCGA-B5-A0K9	UCEC	TCGA	PSSSS	DEG_SPOP_SBC_1	863:867	Mutation rewiring degron network	0.0833
p.A854T	DO42097	UCEC	ICGC	PSSSS	DEG_SPOP_SBC_1	863:867	Mutation rewiring degron network	0.0833
p.A854T	SIDM01113	Other Sarcomas	GDSC	PSSSS	DEG_SPOP_SBC_1	863:867	Mutation rewiring degron network	0.0833
p.G853D	TCGA-BG-A0LX	UCEC	TCGA	PSSSS	DEG_SPOP_SBC_1	863:867	Mutation rewiring degron network	0.0556
p.G853D	DO41919	UCEC	ICGC	PSSSS	DEG_SPOP_SBC_1	863:867	Mutation rewiring degron network	0.0556
p.P856L	TCGA-EE-A2GI	SKCM	TCGA	PSSSS	DEG_SPOP_SBC_1	863:867	Mutation rewiring degron network	0.1389
p.P856L	TCGA-YD-A9TA	SKCM	TCGA	PSSSS	DEG_SPOP_SBC_1	863:867	Mutation rewiring degron network	0.1389
p.P856L	DO222753	MELA	ICGC	PSSSS	DEG_SPOP_SBC_1	863:867	Mutation rewiring degron network	0.1389
p.P856L	DO37410	SKCM	ICGC	PSSSS	DEG_SPOP_SBC_1	863:867	Mutation rewiring degron network	0.1389
p.P856L	DO219503	SKCM	ICGC	PSSSS	DEG_SPOP_SBC_1	863:867	Mutation rewiring degron network	0.1389
p.V776I	TCGA-MX-A5UJ	STAD	TCGA	VSTST	DEG_SPOP_SBC_1	776:780	Mutation altering degron motif	0.7076
p.V776I	DO48547	STAD	ICGC	VSTST	DEG_SPOP_SBC_1	776:780	Mutation altering degron motif	0.7076
p.N859S	DO233082	GACA	ICGC	PSSSS	DEG_SPOP_SBC_1	863:867	Mutation rewiring degron network	0.2222
p.S779R	DO229045	LICA	ICGC	VSTST	DEG_SPOP_SBC_1	776:780	Mutation altering degron motif	0.7427
p.T788M	DO35442	PACA	ICGC	VSTST	DEG_SPOP_SBC_1	776:780	Mutation rewiring degron network	0.1111
p.S782L	SIDM01007	T-Lymphoblastic Leukemia	GDSC	VSTST	DEG_SPOP_SBC_1	776:780	Mutation rewiring degron network	0.2778
p.S782L	ACH-002256	Leukemia	CCLE	VSTST	DEG_SPOP_SBC_1	776:780	Mutation rewiring degron network	0.2778
p.S782L	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	VSTST	DEG_SPOP_SBC_1	776:780	Mutation rewiring degron network	0.2778
p.V855I	Daudi	haematopoietic and lymphoid tissue	COSMIC	PSSSS	DEG_SPOP_SBC_1	863:867	Mutation rewiring degron network	0.1111
p.S775L	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	VSTST	DEG_SPOP_SBC_1	776:780	Mutation rewiring degron network	0.3056

Kaplan plot for ASAP1 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ASAP1

UniProt ID: Q9ULH1

Entrez ID: 50807

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for ASAP1 in