DegronMD - Q9ULJ6(ZMIZ1)

ZMIZ1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P508A	TCGA-14-1396	GBM	TCGA	PTPPMT	DEG_SCF_FBW7_1	516:521	Mutation rewiring degron network	0.1111
p.P508A	DO11429	GBM	ICGC	PTPPMT	DEG_SCF_FBW7_1	516:521	Mutation rewiring degron network	0.1111
p.Y529H	TCGA-24-2035	OV	TCGA	PTPPMT	DEG_SCF_FBW7_1	516:521	Mutation rewiring degron network	0.1111
p.Y529H	DO29598	OV	ICGC	PTPPMT	DEG_SCF_FBW7_1	516:521	Mutation rewiring degron network	0.1111
p.Y529S	TCGA-24-2035	OV	TCGA	PTPPMT	DEG_SCF_FBW7_1	516:521	Mutation rewiring degron network	0.1111
p.Y529S	DO29598	OV	ICGC	PTPPMT	DEG_SCF_FBW7_1	516:521	Mutation rewiring degron network	0.1111
p.G523W	TCGA-BF-A1PU	SKCM	TCGA	PTPPMT	DEG_SCF_FBW7_1	516:521	Mutation rewiring degron network	0.2778
p.G523W	DO50278	SKCM	ICGC	PTPPMT	DEG_SCF_FBW7_1	516:521	Mutation rewiring degron network	0.2778
p.Y507C	TCGA-BR-4361	STAD	TCGA	PTPPMT	DEG_SCF_FBW7_1	516:521	Mutation rewiring degron network	0.0833
p.Y507C	DO38887	STAD	ICGC	PTPPMT	DEG_SCF_FBW7_1	516:521	Mutation rewiring degron network	0.0833
p.N506T	TCGA-ER-A194	SKCM	TCGA	PTPPMT	DEG_SCF_FBW7_1	516:521	Mutation rewiring degron network	0.0556
p.N506T	DO47646	SKCM	ICGC	PTPPMT	DEG_SCF_FBW7_1	516:521	Mutation rewiring degron network	0.0556
p.N506S	DO222998	BTCA	ICGC	PTPPMT	DEG_SCF_FBW7_1	516:521	Mutation rewiring degron network	0.0556
p.K516N	HOS	bone	COSMIC	PTPPMT	DEG_SCF_FBW7_1	516:521	Mutation altering degron motif	0.6918

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*NOTE: the Kaplan plots were collected from OncoLnc