DegronMD - Q9ULS6(KCNS2)

KCNS2

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GO - Biological processes (BP): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R477P	TCGA-3N-A9WC	SKCM	TCGA	SLR	DEG_APCC_TPR_1	475:477	Mutation altering degron motif	0.7512
p.R477P	DO51234	SKCM	ICGC	SLR	DEG_APCC_TPR_1	475:477	Mutation altering degron motif	0.7512
p.R477C	TCGA-58-A46L	LUSC	TCGA	SLR	DEG_APCC_TPR_1	475:477	Mutation altering degron motif	0.8301
p.R477C	DO45434	LUSC	ICGC	SLR	DEG_APCC_TPR_1	475:477	Mutation altering degron motif	0.8301
p.S468C	DO233260	GACA	ICGC	SLR	DEG_APCC_TPR_1	475:477	Mutation rewiring degron network	0.1389
p.E469K	SIDM00140	Melanoma	GDSC	SLR	DEG_APCC_TPR_1	475:477	Mutation rewiring degron network	0.1667
p.E469K	ACH-000968	Skin Cancer	CCLE	SLR	DEG_APCC_TPR_1	475:477	Mutation rewiring degron network	0.1667
p.E469K	COLO-792	skin	COSMIC	SLR	DEG_APCC_TPR_1	475:477	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc