DegronMD - Q9ULX3(NOB1)

NOB1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S380G	TCGA-BR-7707	STAD	TCGA	VSPFVE	LIG_APCC_ABBA_1	370:375	Mutation rewiring degron network	0.1944
p.S380G	DO38487	STAD	ICGC	VSPFVE	LIG_APCC_ABBA_1	370:375	Mutation rewiring degron network	0.1944
p.N360K	TCGA-D8-A1XK	BRCA	TCGA	VSPFVE	LIG_APCC_ABBA_1	370:375	Mutation rewiring degron network	0.0556
p.N360K	DO4749	BRCA	ICGC	VSPFVE	LIG_APCC_ABBA_1	370:375	Mutation rewiring degron network	0.0556
p.P364L	TCGA-FS-A1ZW	SKCM	TCGA	VSPFVE	LIG_APCC_ABBA_1	370:375	Mutation rewiring degron network	0.1667
p.P364L	DO37519	SKCM	ICGC	VSPFVE	LIG_APCC_ABBA_1	370:375	Mutation rewiring degron network	0.1667
p.R381C	TCGA-G4-6628	COAD	TCGA	VSPFVE	LIG_APCC_ABBA_1	370:375	Mutation rewiring degron network	0.1667
p.R381C	DO10132	COAD	ICGC	VSPFVE	LIG_APCC_ABBA_1	370:375	Mutation rewiring degron network	0.1667
p.P372L	TCGA-GJ-A6C0	LIHC	TCGA	VSPFVE	LIG_APCC_ABBA_1	370:375	Mutation altering degron motif	0.6471
p.P372L	DO48486	LIHC	ICGC	VSPFVE	LIG_APCC_ABBA_1	370:375	Mutation altering degron motif	0.6471
p.A368S	DO229024	LICA	ICGC	VSPFVE	LIG_APCC_ABBA_1	370:375	Mutation rewiring degron network	0.2778
p.N360S	SIDM00770	Small Cell Lung Carcinoma	GDSC	VSPFVE	LIG_APCC_ABBA_1	370:375	Mutation rewiring degron network	0.0556
p.N360S	ACH-000559	Lung Cancer	CCLE	VSPFVE	LIG_APCC_ABBA_1	370:375	Mutation rewiring degron network	0.0556
p.N360S	NCI-H1836	lung	COSMIC	VSPFVE	LIG_APCC_ABBA_1	370:375	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc