DegronMD - Q9ULZ2(STAP1)

STAP1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L24I	TCGA-2Z-A9J8	KIRP	TCGA	LPLYFE	LIG_APCC_ABBA_1	24:29	Mutation altering degron motif	0.6063
p.L24I	DO219660	KIRP	ICGC	LPLYFE	LIG_APCC_ABBA_1	24:29	Mutation altering degron motif	0.6063
p.K20N	TCGA-A5-A0G1	UCEC	TCGA	LPLYFE	LIG_APCC_ABBA_1	24:29	Mutation substituting flanking lysine	0.3333
p.K20N	DO42472	UCEC	ICGC	LPLYFE	LIG_APCC_ABBA_1	24:29	Mutation substituting flanking lysine	0.3333
p.A23D	TCGA-A5-A0G1	UCEC	TCGA	LPLYFE	LIG_APCC_ABBA_1	24:29	Mutation rewiring degron network	0.3056
p.A23D	DO42472	UCEC	ICGC	LPLYFE	LIG_APCC_ABBA_1	24:29	Mutation rewiring degron network	0.3056
p.E17K	TCGA-D3-A3ML	SKCM	TCGA	LPLYFE	LIG_APCC_ABBA_1	24:29	Mutation rewiring degron network	0.1389
p.E17K	DO47413	SKCM	ICGC	LPLYFE	LIG_APCC_ABBA_1	24:29	Mutation rewiring degron network	0.1389
p.G38E	TCGA-FW-A3R5	SKCM	TCGA	LPLYFE	LIG_APCC_ABBA_1	24:29	Mutation rewiring degron network	0.0833
p.G38E	DO37406	SKCM	ICGC	LPLYFE	LIG_APCC_ABBA_1	24:29	Mutation rewiring degron network	0.0833
p.R36Q	DO871	BOCA	ICGC	LPLYFE	LIG_APCC_ABBA_1	24:29	Mutation rewiring degron network	0.1389
p.I14F	DO233739	GACA	ICGC	LPLYFE	LIG_APCC_ABBA_1	24:29	Mutation rewiring degron network	0.0556
p.A23S	DO229025	LICA	ICGC	LPLYFE	LIG_APCC_ABBA_1	24:29	Mutation rewiring degron network	0.3056
p.I34M	SIDM00806	Osteosarcoma	GDSC	LPLYFE	LIG_APCC_ABBA_1	24:29	Mutation rewiring degron network	0.1944
p.I34M	HOS	bone	COSMIC	LPLYFE	LIG_APCC_ABBA_1	24:29	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc