DegronMD - Q9UNF0(PACSIN2)

PACSIN2

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D397N	TCGA-BR-4370	STAD	TCGA	PFSST	DEG_SPOP_SBC_1	406:410	Mutation rewiring degron network	0.0833
p.E402Q	TCGA-CV-6961	HNSC	TCGA	PFSST	DEG_SPOP_SBC_1	406:410	Mutation rewiring degron network	0.2222
p.F419L	TCGA-KQ-A41N	BLCA	TCGA	PFSST	DEG_SPOP_SBC_1	406:410	Mutation rewiring degron network	0.0833
p.G409A	DO4963	BRCA	ICGC	PFSST	DEG_SPOP_SBC_1	406:410	Mutation altering degron motif	0.754
p.E418K	DO5936	BRCA	ICGC	PFSST	DEG_SPOP_SBC_1	406:410	Mutation rewiring degron network	0.1111
p.D420V	DO233784	GACA	ICGC	PFSST	DEG_SPOP_SBC_1	406:410	Mutation rewiring degron network	0.0556
p.T396N	DO228948	LICA	ICGC	PFSST	DEG_SPOP_SBC_1	406:410	Mutation blocking phosphorylation signal	0.5
p.N405K	DO228985	LICA	ICGC	PFSST	DEG_SPOP_SBC_1	406:410	Mutation rewiring degron network	0.3056
p.P418S	DO222843	MELA	ICGC	PFSST	DEG_SPOP_SBC_1	406:410	Mutation rewiring degron network	0.1111

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc