DegronMD - Q9UPS8(ANKRD26)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S1644I	TCGA-17-Z031	LUAD	TCGA	VISTS	DEG_SPOP_SBC_1	1632:1636	Mutation rewiring degron network	0.1111
p.I1626V	TCGA-AO-A128	BRCA	TCGA	VISTS	DEG_SPOP_SBC_1	1632:1636	Mutation rewiring degron network	0.1667
p.I1626V	DO5326	BRCA	ICGC	VISTS	DEG_SPOP_SBC_1	1632:1636	Mutation rewiring degron network	0.1667
p.L1625F	TCGA-AP-A0LM	UCEC	TCGA	VISTS	DEG_SPOP_SBC_1	1632:1636	Mutation rewiring degron network	0.1389
p.L1625F	DO43306	UCEC	ICGC	VISTS	DEG_SPOP_SBC_1	1632:1636	Mutation rewiring degron network	0.1389
p.M1645I	TCGA-BR-4184	STAD	TCGA	VISTS	DEG_SPOP_SBC_1	1632:1636	Mutation rewiring degron network	0.0833
p.M1645I	DO38328	STAD	ICGC	VISTS	DEG_SPOP_SBC_1	1632:1636	Mutation rewiring degron network	0.0833
p.E1646D	TCGA-EI-6917	READ	TCGA	VISTS	DEG_SPOP_SBC_1	1632:1636	Mutation rewiring degron network	0.0556
p.E1646D	TCGA-EY-A1G8	UCEC	TCGA	VISTS	DEG_SPOP_SBC_1	1632:1636	Mutation rewiring degron network	0.0556
p.E1646D	DO36881	READ	ICGC	VISTS	DEG_SPOP_SBC_1	1632:1636	Mutation rewiring degron network	0.0556
p.E1646D	DO43578	UCEC	ICGC	VISTS	DEG_SPOP_SBC_1	1632:1636	Mutation rewiring degron network	0.0556
p.T1635I	TCGA-ER-A42L	SKCM	TCGA	VISTS	DEG_SPOP_SBC_1	1632:1636	Mutation altering degron motif	0.7078
p.T1635I	DO223910	SKCM	ICGC	VISTS	DEG_SPOP_SBC_1	1632:1636	Mutation altering degron motif	0.7078
p.S1634Y	DO222884	COCA	ICGC	VISTS	DEG_SPOP_SBC_1	1632:1636	Mutation altering degron motif	0.712
p.S1644R	DO229022	LICA	ICGC	VISTS	DEG_SPOP_SBC_1	1632:1636	Mutation rewiring degron network	0.1111
p.N1642D	SIDM00621	Ewing's Sarcoma	GDSC	VISTS	DEG_SPOP_SBC_1	1632:1636	Mutation rewiring degron network	0.1667
p.N1642D	SIDM00118	Colorectal Carcinoma	GDSC	VISTS	DEG_SPOP_SBC_1	1632:1636	Mutation rewiring degron network	0.1667
p.N1642D	HCC2998	large intestine	COSMIC	VISTS	DEG_SPOP_SBC_1	1632:1636	Mutation rewiring degron network	0.1667
p.N1642D	EW-13	bone	COSMIC	VISTS	DEG_SPOP_SBC_1	1632:1636	Mutation rewiring degron network	0.1667

Kaplan plot for ANKRD26 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ANKRD26

UniProt ID: Q9UPS8

Entrez ID: 22852

Protein name: Ankyrin repeat domain-containing protein 26

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for ANKRD26 in