DegronMD - Q9UPU7(TBC1D2B)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V553L	TCGA-AX-A2HJ	UCEC	TCGA	MKTPVCS	DEG_SCF_FBW7_1	549:555	Mutation altering degron motif	0.5654
p.V553L	DO42105	UCEC	ICGC	MKTPVCS	DEG_SCF_FBW7_1	549:555	Mutation altering degron motif	0.5654
p.D557N	TCGA-BF-A5EO	SKCM	TCGA	MKTPVCS	DEG_SCF_FBW7_1	549:555	Mutation rewiring degron network	0.2778
p.D557N	DO219450	SKCM	ICGC	MKTPVCS	DEG_SCF_FBW7_1	549:555	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons