DegronMD - Q9UPW0(FOXJ3)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.M564I	TCGA-AX-A06F	UCEC	TCGA	PPGY	ITCH	566:569	Mutation rewiring degron network	0.2778
p.A589V	TCGA-AX-A0J1	UCEC	TCGA	LSTPGTT	DEG_SCF_FBW7_1	576:582	Mutation rewiring degron network	0.1389
p.H586Y	TCGA-CV-7235	HNSC	TCGA	LSTPGTT	DEG_SCF_FBW7_1	576:582	Mutation rewiring degron network	0.2222
p.P579A	TCGA-DK-A1AC	BLCA	TCGA	LSTPGTT	DEG_SCF_FBW7_1	576:582	Mutation altering degron motif	0.7503
p.G568D	TCGA-EO-A22X	UCEC	TCGA	PPGY	ITCH	566:569	Mutation altering degron motif	0.6087
p.P560S	TCGA-OD-A75X	SKCM	TCGA	PPGY	ITCH	566:569	Mutation rewiring degron network	0.1667
p.R570W	DO227906	COCA	ICGC	LSTPGTT	DEG_SCF_FBW7_1	576:582	Mutation rewiring degron network	0.1667
p.R570W	DO227906	COCA	ICGC	PPGY	ITCH	566:569	Mutation rewiring degron network	0.3056
p.R570W	DO234462	ESAD	ICGC	LSTPGTT	DEG_SCF_FBW7_1	576:582	Mutation rewiring degron network	0.1667
p.R570W	DO234462	ESAD	ICGC	PPGY	ITCH	566:569	Mutation rewiring degron network	0.3056
p.R570W	DO35083	PACA	ICGC	LSTPGTT	DEG_SCF_FBW7_1	576:582	Mutation rewiring degron network	0.1667
p.R570W	DO35083	PACA	ICGC	PPGY	ITCH	566:569	Mutation rewiring degron network	0.3056
p.R570W	DO228138	PBCA	ICGC	LSTPGTT	DEG_SCF_FBW7_1	576:582	Mutation rewiring degron network	0.1667
p.R570W	DO228138	PBCA	ICGC	PPGY	ITCH	566:569	Mutation rewiring degron network	0.3056
p.R570W	DO38487	STAD	ICGC	LSTPGTT	DEG_SCF_FBW7_1	576:582	Mutation rewiring degron network	0.1667
p.R570W	DO38487	STAD	ICGC	PPGY	ITCH	566:569	Mutation rewiring degron network	0.3056
p.P575T	DO228924	LICA	ICGC	LSTPGTT	DEG_SCF_FBW7_1	576:582	Mutation rewiring degron network	0.3056
p.P575T	DO228924	LICA	ICGC	PPGY	ITCH	566:569	Mutation rewiring degron network	0.1667
p.D583H	DO219217	LUSC	ICGC	LSTPGTT	DEG_SCF_FBW7_1	576:582	Mutation rewiring degron network	0.3056
p.P563L	DO222546	MELA	ICGC	PPGY	ITCH	566:569	Mutation rewiring degron network	0.25
p.S572F	DO50287	SKCM	ICGC	LSTPGTT	DEG_SCF_FBW7_1	576:582	Mutation rewiring degron network	0.2222
p.S572F	DO50287	SKCM	ICGC	PPGY	ITCH	566:569	Mutation rewiring degron network	0.25
p.R571C	DO48032	STAD	ICGC	LSTPGTT	DEG_SCF_FBW7_1	576:582	Mutation rewiring degron network	0.1944
p.R571C	DO48032	STAD	ICGC	PPGY	ITCH	566:569	Mutation rewiring degron network	0.2778
p.R571C	DO40978	UCEC	ICGC	LSTPGTT	DEG_SCF_FBW7_1	576:582	Mutation rewiring degron network	0.1944
p.R571C	DO40978	UCEC	ICGC	PPGY	ITCH	566:569	Mutation rewiring degron network	0.2778
p.M562R	SU-DHL-8	NS	COSMIC	PPGY	ITCH	566:569	Mutation rewiring degron network	0.2222

Kaplan plot for FOXJ3 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

FOXJ3

UniProt ID: Q9UPW0

Entrez ID: 22887

Protein name: Forkhead box protein J3

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for FOXJ3 in