DegronMD - Q9Y261(FOXA2)

FOXA2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G326R	TCGA-EB-A6QY	SKCM	TCGA	KRGGLGELK	DEG_APCC_DBOX_1	315:323	Mutation rewiring degron network	0.25
p.G326R	DO48702	SKCM	ICGC	KRGGLGELK	DEG_APCC_DBOX_1	315:323	Mutation rewiring degron network	0.25
p.S312W	TCGA-FD-A43X	BLCA	TCGA	KRGGLGELK	DEG_APCC_DBOX_1	315:323	Mutation rewiring degron network	0.25
p.S312W	DO44067	BLCA	ICGC	KRGGLGELK	DEG_APCC_DBOX_1	315:323	Mutation rewiring degron network	0.25
p.S312W	ACH-001997	Bile Duct Cancer	CCLE	KRGGLGELK	DEG_APCC_DBOX_1	315:323	Mutation rewiring degron network	0.25
p.P316L	DO223436	CLLE	ICGC	KRGGLGELK	DEG_APCC_DBOX_1	315:323	Mutation altering degron motif	0.7582
p.C317F	DO222446	ESCA	ICGC	KRGGLGELK	DEG_APCC_DBOX_1	315:323	Mutation altering degron motif	0.7108
p.T331M	DO233002	GACA	ICGC	KRGGLGELK	DEG_APCC_DBOX_1	315:323	Mutation rewiring degron network	0.1111
p.G324S	DO220877	MELA	ICGC	KRGGLGELK	DEG_APCC_DBOX_1	315:323	Mutation rewiring degron network	0.3056
p.H314R	ACH-000574	Ovarian Cancer	CCLE	KRGGLGELK	DEG_APCC_DBOX_1	315:323	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc