DegronMD - Q9Y2F9(BTBD3)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S76R	TCGA-49-AARE	LUAD	TCGA	ANSSS	DEG_SPOP_SBC_1	73:77	Mutation altering degron motif	0.7427
p.S76R	DO218922	LUAD	ICGC	ANSSS	DEG_SPOP_SBC_1	73:77	Mutation altering degron motif	0.7427
p.K27N	TCGA-AP-A059	UCEC	TCGA	ANTSS	DEG_SPOP_SBC_1	33:37	Mutation blocking ubiquitination signal	0.6111
p.K27N	DO41361	UCEC	ICGC	ANTSS	DEG_SPOP_SBC_1	33:37	Mutation blocking ubiquitination signal	0.6111
p.K71N	TCGA-AX-A2HD	UCEC	TCGA	ANSSS	DEG_SPOP_SBC_1	73:77	Mutation rewiring degron network	0.2778
p.K71N	DO42608	UCEC	ICGC	ANSSS	DEG_SPOP_SBC_1	73:77	Mutation rewiring degron network	0.2778
p.P68L	TCGA-IN-A6RI	STAD	TCGA	ANSSS	DEG_SPOP_SBC_1	73:77	Mutation rewiring degron network	0.1944
p.P68L	DO51736	STAD	ICGC	ANSSS	DEG_SPOP_SBC_1	73:77	Mutation rewiring degron network	0.1944
p.S79R	DO225028	BRCA	ICGC	ANSSS	DEG_SPOP_SBC_1	73:77	Mutation rewiring degron network	0.2778
p.R69L	DO229027	LICA	ICGC	ANSSS	DEG_SPOP_SBC_1	73:77	Mutation rewiring degron network	0.2222
p.I66T	SIDM00328	Esophageal Squamous Cell Carcinoma	GDSC	ANSSS	DEG_SPOP_SBC_1	73:77	Mutation rewiring degron network	0.1389
p.I66T	ACH-000605	Esophageal Cancer	CCLE	ANSSS	DEG_SPOP_SBC_1	73:77	Mutation rewiring degron network	0.1389
p.I66T	ACH-002019	Cervical Cancer	CCLE	ANSSS	DEG_SPOP_SBC_1	73:77	Mutation rewiring degron network	0.1389
p.I66T	TE-6	oesophagus	COSMIC	ANSSS	DEG_SPOP_SBC_1	73:77	Mutation rewiring degron network	0.1389
p.S38I	SIDM01205	Acute Myeloid Leukemia	GDSC	ANTSS	DEG_SPOP_SBC_1	33:37	Mutation blocking phosphorylation signal	0.75
p.S38I	ACH-002314	Leukemia	CCLE	ANTSS	DEG_SPOP_SBC_1	33:37	Mutation blocking phosphorylation signal	0.75

Kaplan plot for BTBD3 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

BTBD3

UniProt ID: Q9Y2F9

Entrez ID: 22903

Protein name: BTB/POZ domain-containing protein 3

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for BTBD3 in