DegronMD - Q9Y2H1(STK38L)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A5T	TCGA-06-5416	GBM	TCGA	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation altering degron motif	0.7139
p.A5T	DO10880	GBM	ICGC	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation altering degron motif	0.7139
p.P12H	TCGA-BF-A1PU	SKCM	TCGA	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.25
p.P12H	DO50278	SKCM	ICGC	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.25
p.N15S	TCGA-CG-4460	STAD	TCGA	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.1667
p.N15S	DO38427	STAD	ICGC	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.1667
p.E19K	TCGA-D3-A3C8	SKCM	TCGA	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.0556
p.E19K	DO47636	SKCM	ICGC	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.0556
p.R18W	TCGA-XK-AAIW	PRAD	TCGA	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.0833
p.R18W	DO27025	LUSC	ICGC	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.0833
p.R18W	DO51407	PRAD	ICGC	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.0833
p.R12W	DO48566	BLCA	ICGC	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.25
p.R12W	DO26858	LUSC	ICGC	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.25
p.R12W	DO41871	UCEC	ICGC	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.25
p.E4Q	DO590	BLCA	ICGC	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.3056
p.T4M	DO233823	GACA	ICGC	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.3056
p.T4M	ACH-001664	Gastric Cancer	CCLE	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.3056
p.P12S	DO220886	MELA	ICGC	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.25
p.V11L	DO32113	OV	ICGC	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.2778
p.T9A	SIDM00958	Chronic Myelogenous Leukemia	GDSC	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation altering degron motif	0.7139
p.T9A	ACH-000920	Leukemia	CCLE	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation altering degron motif	0.7139
p.T9A	CML-T1	haematopoietic and lymphoid tissue	COSMIC	AGTTT	DEG_SPOP_SBC_1	5:9	Mutation altering degron motif	0.7139

Kaplan plot for STK38L in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

STK38L

UniProt ID: Q9Y2H1

Entrez ID: 23012

Protein name: Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for STK38L in