DegronMD - Q9Y316(MEMO1)

MEMO1

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.W114S	TCGA-24-1846	OV	TCGA	YRTPLYDLR	DEG_APCC_DBOX_1	96:104	Mutation rewiring degron network	0.0556
p.R104C	TCGA-AN-A046	BRCA	TCGA	YRTPLYDLR	DEG_APCC_DBOX_1	96:104	Mutation altering degron motif	0.719
p.D102Y	TCGA-BS-A0TC	UCEC	TCGA	YRTPLYDLR	DEG_APCC_DBOX_1	96:104	Mutation altering degron motif	0.6214
p.R104H	TCGA-BS-A0UV	UCEC	TCGA	YRTPLYDLR	DEG_APCC_DBOX_1	96:104	Mutation altering degron motif	0.7133
p.R104H	TCGA-D1-A103	UCEC	TCGA	YRTPLYDLR	DEG_APCC_DBOX_1	96:104	Mutation altering degron motif	0.7133
p.R104H	SIDM00951	T-Lymphoblastic Leukemia	GDSC	YRTPLYDLR	DEG_APCC_DBOX_1	96:104	Mutation altering degron motif	0.7133
p.R104H	ACH-002222	Leukemia	CCLE	YRTPLYDLR	DEG_APCC_DBOX_1	96:104	Mutation altering degron motif	0.7133
p.R104H	CTV-1	haematopoietic and lymphoid tissue	COSMIC	YRTPLYDLR	DEG_APCC_DBOX_1	96:104	Mutation altering degron motif	0.7133
p.R104L	TCGA-D1-A16X	UCEC	TCGA	YRTPLYDLR	DEG_APCC_DBOX_1	96:104	Mutation altering degron motif	0.7316
p.D106Y	TCGA-DK-A6AW	BLCA	TCGA	YRTPLYDLR	DEG_APCC_DBOX_1	96:104	Mutation rewiring degron network	0.2778
p.W91S	DO32718	OV	ICGC	YRTPLYDLR	DEG_APCC_DBOX_1	96:104	Mutation rewiring degron network	0.1944
p.K92E	SNU-182	liver	COSMIC	YRTPLYDLR	DEG_APCC_DBOX_1	96:104	Mutation rewiring degron network	0.2222
p.R107H	CTV-1	haematopoietic and lymphoid tissue	COSMIC	YRTPLYDLR	DEG_APCC_DBOX_1	96:104	Mutation rewiring degron network	0.25

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc