DegronMD - Q9Y365(STARD10)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E224K	TCGA-B5-A0JY	UCEC	TCGA	KPWLHPE	LIG_APCC_ABBAyCdc20_2	234:240	Mutation rewiring degron network	0.0556
p.E224K	TCGA-EY-A215	UCEC	TCGA	KPWLHPE	LIG_APCC_ABBAyCdc20_2	234:240	Mutation rewiring degron network	0.0556
p.E224K	DO8938	COAD	ICGC	KPWLHPE	LIG_APCC_ABBAyCdc20_2	234:240	Mutation rewiring degron network	0.0556
p.E224K	DO223053	ESCA	ICGC	KPWLHPE	LIG_APCC_ABBAyCdc20_2	234:240	Mutation rewiring degron network	0.0556
p.E224K	DO232761	PBCA	ICGC	KPWLHPE	LIG_APCC_ABBAyCdc20_2	234:240	Mutation rewiring degron network	0.0556
p.E224K	DO43041	UCEC	ICGC	KPWLHPE	LIG_APCC_ABBAyCdc20_2	234:240	Mutation rewiring degron network	0.0556
p.E224K	DO42665	UCEC	ICGC	KPWLHPE	LIG_APCC_ABBAyCdc20_2	234:240	Mutation rewiring degron network	0.0556
p.P245S	TCGA-D3-A8GB	SKCM	TCGA	KPWLHPE	LIG_APCC_ABBAyCdc20_2	234:240	Mutation rewiring degron network	0.1944
p.R229Q	DO222864	COCA	ICGC	KPWLHPE	LIG_APCC_ABBAyCdc20_2	234:240	Mutation rewiring degron network	0.1944
p.D240E	DO228986	LICA	ICGC	KPWLHPE	LIG_APCC_ABBAyCdc20_2	234:240	Mutation altering degron motif	0.6758
p.A233E	DO229037	LICA	ICGC	KPWLHPE	LIG_APCC_ABBAyCdc20_2	234:240	Mutation rewiring degron network	0.3056
p.L237P	SIDM00070	B-Cell Non-Hodgkin's Lymphoma	GDSC	KPWLHPE	LIG_APCC_ABBAyCdc20_2	234:240	Mutation altering degron motif	0.7582
p.L237P	ACH-002393	Lymphoma	CCLE	KPWLHPE	LIG_APCC_ABBAyCdc20_2	234:240	Mutation altering degron motif	0.7582
p.L237P	CRO-AP3	NS	COSMIC	KPWLHPE	LIG_APCC_ABBAyCdc20_2	234:240	Mutation altering degron motif	0.7582
p.L230Q	SIDM01609	Endometrial Carcinoma	GDSC	KPWLHPE	LIG_APCC_ABBAyCdc20_2	234:240	Mutation rewiring degron network	0.2222
p.L230Q	ACH-000972	Endometrial/Uterine Cancer	CCLE	KPWLHPE	LIG_APCC_ABBAyCdc20_2	234:240	Mutation rewiring degron network	0.2222
p.F233L	ACH-001409	Bladder Cancer	CCLE	KPWLHPE	LIG_APCC_ABBAyCdc20_2	234:240	Mutation rewiring degron network	0.3056
p.D235N	SW684	soft tissue	COSMIC	KPWLHPE	LIG_APCC_ABBAyCdc20_2	234:240	Mutation altering degron motif	0.6932
p.D239E	NCI-H2135	lung	COSMIC	KPWLHPE	LIG_APCC_ABBAyCdc20_2	234:240	Mutation altering degron motif	0.6758

Kaplan plot for STARD10 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

STARD10

UniProt ID: Q9Y365

Entrez ID: 10809

Protein name: START domain-containing protein 10 (StARD10) (Antigen NY-CO-28) (PCTP-like protein) (PCTP-L) (Serologically defined colon cancer antigen 28) (StAR-related lipid transfer protein 10)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for STARD10 in