DegronMD - Q9Y3D5(MRPS18C)

MRPS18C

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A22T	TCGA-55-7815	LUAD	TCGA	GRKKLTHLV	DEG_APCC_DBOX_1	12:20	Mutation rewiring degron network	0.2778
p.A22T	DO24537	LUAD	ICGC	GRKKLTHLV	DEG_APCC_DBOX_1	12:20	Mutation rewiring degron network	0.2778
p.L16S	TCGA-EE-A3J7	SKCM	TCGA	GRKKLTHLV	DEG_APCC_DBOX_1	12:20	Mutation altering degron motif	0.7667
p.L16S	DO48770	SKCM	ICGC	GRKKLTHLV	DEG_APCC_DBOX_1	12:20	Mutation altering degron motif	0.7667
p.G9S	TCGA-UY-A9PE	BLCA	TCGA	GRKKLTHLV	DEG_APCC_DBOX_1	12:20	Mutation rewiring degron network	0.25
p.G9S	DO219043	BLCA	ICGC	GRKKLTHLV	DEG_APCC_DBOX_1	12:20	Mutation rewiring degron network	0.25
p.G9V	TCGA-UY-A9PE	BLCA	TCGA	GRKKLTHLV	DEG_APCC_DBOX_1	12:20	Mutation rewiring degron network	0.25
p.G9V	DO219043	BLCA	ICGC	GRKKLTHLV	DEG_APCC_DBOX_1	12:20	Mutation rewiring degron network	0.25
p.A23V	DO234150	ESAD	ICGC	GRKKLTHLV	DEG_APCC_DBOX_1	12:20	Mutation rewiring degron network	0.25
p.V24F	DO228974	LICA	ICGC	GRKKLTHLV	DEG_APCC_DBOX_1	12:20	Mutation rewiring degron network	0.2222
p.G10V	DO229036	LICA	ICGC	GRKKLTHLV	DEG_APCC_DBOX_1	12:20	Mutation rewiring degron network	0.2778
p.P29S	SIDM01028	Esophageal Squamous Cell Carcinoma	GDSC	GRKKLTHLV	DEG_APCC_DBOX_1	12:20	Mutation rewiring degron network	0.0833
p.P29S	ACH-000809	Esophageal Cancer	CCLE	GRKKLTHLV	DEG_APCC_DBOX_1	12:20	Mutation rewiring degron network	0.0833
p.P29S	KYSE-410	oesophagus	COSMIC	GRKKLTHLV	DEG_APCC_DBOX_1	12:20	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc