DegronMD - Q9Y580(RBM7)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.H103R	TCGA-BR-6563	STAD	TCGA	PTSTS	DEG_SPOP_SBC_1	109:113	Mutation rewiring degron network	0.1667
p.H103R	DO38364	STAD	ICGC	PTSTS	DEG_SPOP_SBC_1	109:113	Mutation rewiring degron network	0.1667
p.E118K	TCGA-EY-A1G8	UCEC	TCGA	PTSTS	DEG_SPOP_SBC_1	109:113	Mutation rewiring degron network	0.1944
p.H103D	DO228562	LICA	ICGC	PTSTS	DEG_SPOP_SBC_1	109:113	Mutation rewiring degron network	0.1667
p.P100S	DO229272	THCA	ICGC	PTSTS	DEG_SPOP_SBC_1	109:113	Mutation rewiring degron network	0.0833
p.T112A	DO229229	THCA	ICGC	PTSTS	DEG_SPOP_SBC_1	109:113	Mutation altering degron motif	0.825
p.E119K	DO43578	UCEC	ICGC	PTSTS	DEG_SPOP_SBC_1	109:113	Mutation rewiring degron network	0.1667
p.G103V	EJM	haematopoietic and lymphoid tissue	COSMIC	PTSTS	DEG_SPOP_SBC_1	109:113	Mutation rewiring degron network	0.1667

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons