DegronMD - Q9Y5J3(HEY1)

HEY1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A49T	TCGA-BG-A222	UCEC	TCGA	PTTSS	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.2222
p.A49T	DO42977	UCEC	ICGC	PTTSS	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.2222
p.S34L	TCGA-K4-A83P	BLCA	TCGA	PTTSS	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.1389
p.S34L	DO49787	BLCA	ICGC	PTTSS	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.1389
p.L36V	DO225215	BRCA	ICGC	PTTSS	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.1944
p.L36V	DO227836	BRCA	ICGC	PTTSS	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.1944
p.C40W	DO49778	KIRP	ICGC	PTTSS	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.3056
p.I50S	DO228207	LICA	ICGC	PTTSS	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.1944
p.D31G	DO50814	LIRI	ICGC	PTTSS	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.0556
p.D31E	DO228382	MALY	ICGC	PTTSS	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.0556
p.I51T	DO29628	OV	ICGC	PTTSS	DEG_SPOP_SBC_1	41:45	Mutation substituting flanking lysine	0.2778
p.R53P	SIDM00600	Thyroid Gland Carcinoma	GDSC	PTTSS	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.1111
p.R53P	ACH-001528	Thyroid Cancer	CCLE	PTTSS	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.1111
p.R53P	IHH-4	thyroid	COSMIC	PTTSS	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.1111
p.G53V	ACH-000921	Lung Cancer	CCLE	PTTSS	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.1111
p.L36I	ACH-000966	Ovarian Cancer	CCLE	PTTSS	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc