DegronMD - Q9Y5S2(CDC42BPB)

CDC42BPB

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E428K	TCGA-BH-A18P	BRCA	TCGA	DRGSLKSIM	DEG_APCC_DBOX_1	411:419	Mutation rewiring degron network	0.0833
p.E428K	DO3346	BRCA	ICGC	DRGSLKSIM	DEG_APCC_DBOX_1	411:419	Mutation rewiring degron network	0.0833
p.T405M	TCGA-IB-7651	PAAD	TCGA	DRGSLKSIM	DEG_APCC_DBOX_1	411:419	Mutation rewiring degron network	0.1667
p.T405M	DO46657	PAAD	ICGC	DRGSLKSIM	DEG_APCC_DBOX_1	411:419	Mutation rewiring degron network	0.1667
p.T405M	DO232224	PBCA	ICGC	DRGSLKSIM	DEG_APCC_DBOX_1	411:419	Mutation rewiring degron network	0.1667
p.I418T	DO35242	PACA	ICGC	DRGSLKSIM	DEG_APCC_DBOX_1	411:419	Mutation altering degron motif	0.7078
p.D411N	SIDM00272	Breast Carcinoma	GDSC	DRGSLKSIM	DEG_APCC_DBOX_1	411:419	Mutation altering degron motif	0.5821
p.D411N	ACH-000910	Breast Cancer	CCLE	DRGSLKSIM	DEG_APCC_DBOX_1	411:419	Mutation altering degron motif	0.5821
p.D411N	MDA-MB-453	breast	COSMIC	DRGSLKSIM	DEG_APCC_DBOX_1	411:419	Mutation altering degron motif	0.5821
p.E428D	SIDM01510	Non-Small Cell Lung Carcinoma	GDSC	DRGSLKSIM	DEG_APCC_DBOX_1	411:419	Mutation rewiring degron network	0.0833
p.E428D	ACH-000925	Lung Cancer	CCLE	DRGSLKSIM	DEG_APCC_DBOX_1	411:419	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc