DegronMD - Q9Y5Z4(HEBP2)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E205K	TCGA-A5-A0G2	UCEC	TCGA	TKENE	DEG_APCC_KENBOX_2	201:205	Mutation altering degron motif	0.591
p.E205K	DO41235	UCEC	ICGC	TKENE	DEG_APCC_KENBOX_2	201:205	Mutation altering degron motif	0.591
p.Q196P	TCGA-CN-6988	HNSC	TCGA	TKENE	DEG_APCC_KENBOX_2	201:205	Mutation rewiring degron network	0.1944
p.Q196P	DO14208	HNSC	ICGC	TKENE	DEG_APCC_KENBOX_2	201:205	Mutation rewiring degron network	0.1944
p.Q196K	TCGA-KQ-A41N	BLCA	TCGA	TKENE	DEG_APCC_KENBOX_2	201:205	Mutation rewiring degron network	0.1944
p.Q196K	DO223588	BLCA	ICGC	TKENE	DEG_APCC_KENBOX_2	201:205	Mutation rewiring degron network	0.1944
p.Q196K	ACH-000649	Kidney Cancer	CCLE	TKENE	DEG_APCC_KENBOX_2	201:205	Mutation rewiring degron network	0.1944
p.L194S	DO233854	GACA	ICGC	TKENE	DEG_APCC_KENBOX_2	201:205	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons