DegronMD - Q9Y675(SNURF)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R27G	TCGA-13-2057	OV	TCGA	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.1667
p.R27G	DO31320	OV	ICGC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.1667
p.V18I	TCGA-2W-A8YY	CESC	TCGA	TTEQHVPEV	DEG_COP1_1	13:21	Mutation altering degron motif	0.7076
p.V18I	DO223732	CESC	ICGC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation altering degron motif	0.7076
p.V18I	DO23320	LINC	ICGC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation altering degron motif	0.7076
p.V18L	TCGA-69-7765	LUAD	TCGA	TTEQHVPEV	DEG_COP1_1	13:21	Mutation altering degron motif	0.6765
p.V18L	DO228952	LICA	ICGC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation altering degron motif	0.6765
p.V18L	DO23580	LUAD	ICGC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation altering degron motif	0.6765
p.R3W	TCGA-AR-A0TZ	BRCA	TCGA	TTEQHVPEV	DEG_COP1_1	13:21	Mutation blocking phosphorylation signal	0.5
p.R3W	DO2287	BRCA	ICGC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation blocking phosphorylation signal	0.5
p.V21L	TCGA-CV-A45Z	HNSC	TCGA	TTEQHVPEV	DEG_COP1_1	13:21	Mutation altering degron motif	0.5654
p.V21L	DO52064	HNSC	ICGC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation altering degron motif	0.5654
p.R12Q	TCGA-DA-A95X	SKCM	TCGA	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.3056
p.R12Q	DO9876	COAD	ICGC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.3056
p.R12Q	DO219480	SKCM	ICGC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.3056
p.R7H	TCGA-DU-6392	LGG	TCGA	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.1667
p.R7H	DO233163	GACA	ICGC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.1667
p.R7H	DO22237	LGG	ICGC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.1667
p.E22D	TCGA-FS-A1ZC	SKCM	TCGA	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.3056
p.E22D	DO37487	SKCM	ICGC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.3056
p.R7C	TCGA-GN-A266	SKCM	TCGA	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.1667
p.R7C	TCGA-W3-AA1R	SKCM	TCGA	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.1667
p.R7C	DO37432	SKCM	ICGC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.1667
p.R7C	DO51275	SKCM	ICGC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.1667
p.R7G	DO1087	BRCA	ICGC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.1667
p.A31V	DO227984	COCA	ICGC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.0556
p.R11G	DO233168	GACA	ICGC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.2778
p.R3Q	DO233671	GACA	ICGC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation blocking phosphorylation signal	0.5
p.V25L	ACH-000847	Gastric Cancer	CCLE	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.2222
p.V25L	HGC-27	stomach	COSMIC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.2222
p.R7S	ACH-001364	Lung Cancer	CCLE	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.1667
p.R7S	NCI-H345	lung	COSMIC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation rewiring degron network	0.1667
p.P19Q	ACH-002175	Lung Cancer	CCLE	TTEQHVPEV	DEG_COP1_1	13:21	Mutation altering degron motif	0.7035
p.P19Q	NCI-H740	lung	COSMIC	TTEQHVPEV	DEG_COP1_1	13:21	Mutation altering degron motif	0.7035

DegronMD: protein-targeted degradation, mutation and drug response to degrons

SNURF

UniProt ID: Q9Y675

Entrez ID: 8926

Protein name: SNRPN upstream reading frame protein

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for SNURF in