DegronMD - Q9Y6B7(AP4B1)

AP4B1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A596T	TCGA-KK-A8IG	PRAD	TCGA	PKTSS	DEG_SPOP_SBC_1	589:593	Mutation rewiring degron network	0.25
p.A596T	DO219331	PRAD	ICGC	PKTSS	DEG_SPOP_SBC_1	589:593	Mutation rewiring degron network	0.25
p.A581S	TCGA-KQ-A41O	BLCA	TCGA	PKTSS	DEG_SPOP_SBC_1	589:593	Mutation rewiring degron network	0.1111
p.A581S	DO223589	BLCA	ICGC	PKTSS	DEG_SPOP_SBC_1	589:593	Mutation rewiring degron network	0.1111
p.S593F	TCGA-WE-A8K6	SKCM	TCGA	PKTSS	DEG_SPOP_SBC_1	589:593	Mutation altering degron motif	0.9093
p.S593F	DO51283	SKCM	ICGC	PKTSS	DEG_SPOP_SBC_1	589:593	Mutation altering degron motif	0.9093
p.G580R	SIDM01187	Breast Carcinoma	GDSC	PKTSS	DEG_SPOP_SBC_1	589:593	Mutation rewiring degron network	0.0833
p.G580R	ACH-000568	Breast Cancer	CCLE	PKTSS	DEG_SPOP_SBC_1	589:593	Mutation rewiring degron network	0.0833
p.G580R	UACC-812	breast	COSMIC	PKTSS	DEG_SPOP_SBC_1	589:593	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc