DegronMD - Q9Y6K0(CEPT1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R50W	TCGA-2W-A8YY	CESC	TCGA	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation rewiring degron network	0.1667
p.R50W	TCGA-EY-A1GK	UCEC	TCGA	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation rewiring degron network	0.1667
p.R50W	TCGA-VQ-A8P2	STAD	TCGA	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation rewiring degron network	0.1667
p.R50W	DO223732	CESC	ICGC	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation rewiring degron network	0.1667
p.R50W	DO51761	STAD	ICGC	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation rewiring degron network	0.1667
p.R50W	DO42985	UCEC	ICGC	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation rewiring degron network	0.1667
p.R50Q	TCGA-2W-A8YY	CESC	TCGA	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation rewiring degron network	0.1667
p.R50Q	DO223732	CESC	ICGC	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation rewiring degron network	0.1667
p.T28I	TCGA-HU-A4GH	STAD	TCGA	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation rewiring degron network	0.0556
p.T28I	DO47743	STAD	ICGC	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation rewiring degron network	0.0556
p.R45T	DO46438	OV	ICGC	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation rewiring degron network	0.3056
p.T40I	SIDM01006	Plasma Cell Myeloma	GDSC	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation altering degron motif	0.8189
p.T40I	SIDM00399	Head and Neck Carcinoma	GDSC	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation altering degron motif	0.8189
p.T40I	SIDM00659	Glioblastoma	GDSC	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation altering degron motif	0.8189
p.T40I	SIDM00676	Bladder Carcinoma	GDSC	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation altering degron motif	0.8189
p.T40I	SIDM01615	Non-Small Cell Lung Carcinoma	GDSC	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation altering degron motif	0.8189
p.R45K	SIDM00135	Breast Carcinoma	GDSC	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation rewiring degron network	0.3056
p.R45K	ACH-000148	Breast Cancer	CCLE	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation rewiring degron network	0.3056
p.R45K	Hs-578-T	breast	COSMIC	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation rewiring degron network	0.3056
p.L32I	SIDM00598	Squamous Cell Lung Carcinoma	GDSC	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation rewiring degron network	0.1667
p.L32I	ACH-000843	Lung Cancer	CCLE	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation rewiring degron network	0.1667
p.L32I	HARA	lung	COSMIC	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation rewiring degron network	0.1667
p.S44P	SIDM01088	Endometrial Carcinoma	GDSC	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation altering degron motif	0.7863
p.S44P	RL95-2	endometrium	COSMIC	LPTPPLS	DEG_SCF_FBW7_1	38:44	Mutation altering degron motif	0.7863

Kaplan plot for CEPT1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CEPT1

UniProt ID: Q9Y6K0

Entrez ID: 10390

Protein name: Choline/ethanolaminephosphotransferase 1 (hCEPT1) (EC 2.7.8.1) (EC 2.7.8.2) (1-alkenyl-2-acylglycerol choline phosphotransferase) (EC 2.7.8.22)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for CEPT1 in