DegronMD - Q9Y6M5(SLC30A1)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D143V	TCGA-37-4141	LUSC	TCGA	DSGHGHS	DEG_SCF_TRCP1_1	143:149	Mutation altering degron motif	0.7785
p.D143V	DO26862	LUSC	ICGC	DSGHGHS	DEG_SCF_TRCP1_1	143:149	Mutation altering degron motif	0.7785
p.F134L	DO229029	LICA	ICGC	DSGHGHS	DEG_SCF_TRCP1_1	143:149	Mutation rewiring degron network	0.0833
p.H155Q	DO229008	LICA	ICGC	DSGHGHS	DEG_SCF_TRCP1_1	143:149	Mutation rewiring degron network	0.1667
p.H150Q	DO230931	LUSC	ICGC	DSGHGHS	DEG_SCF_TRCP1_1	143:149	Mutation rewiring degron network	0.3056
p.H150Q	DO224548	LUSC	ICGC	DSGHGHS	DEG_SCF_TRCP1_1	143:149	Mutation rewiring degron network	0.3056
p.H135Y	DO31420	OV	ICGC	DSGHGHS	DEG_SCF_TRCP1_1	143:149	Mutation rewiring degron network	0.1111
p.H137Y	ACH-000945	Lung Cancer	CCLE	DSGHGHS	DEG_SCF_TRCP1_1	143:149	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons