DegronMD - Q9Y6N6(LAMC3)

LAMC3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P903L	TCGA-56-7730	LUSC	TCGA	LQPGRGCR	SCF_FBXL2	908:915	Mutation rewiring degron network	0.1944
p.P903L	DO26617	LUSC	ICGC	LQPGRGCR	SCF_FBXL2	908:915	Mutation rewiring degron network	0.1944
p.R900H	TCGA-A5-A0G1	UCEC	TCGA	LQPGRGCR	SCF_FBXL2	908:915	Mutation rewiring degron network	0.1111
p.R900H	DO42472	UCEC	ICGC	LQPGRGCR	SCF_FBXL2	908:915	Mutation rewiring degron network	0.1111
p.R915W	TCGA-AA-3672	COAD	TCGA	LQPGRGCR	SCF_FBXL2	908:915	Mutation altering degron motif	0.8634
p.R915W	DO9010	COAD	ICGC	LQPGRGCR	SCF_FBXL2	908:915	Mutation altering degron motif	0.8634
p.G913S	TCGA-EE-A29T	SKCM	TCGA	LQPGRGCR	SCF_FBXL2	908:915	Mutation altering degron motif	0.6993
p.G913S	DO37742	SKCM	ICGC	LQPGRGCR	SCF_FBXL2	908:915	Mutation altering degron motif	0.6993
p.P903H	TCGA-FS-A1ZZ	SKCM	TCGA	LQPGRGCR	SCF_FBXL2	908:915	Mutation rewiring degron network	0.1944
p.P903H	DO37412	SKCM	ICGC	LQPGRGCR	SCF_FBXL2	908:915	Mutation rewiring degron network	0.1944
p.P921Q	DO224914	BRCA	ICGC	LQPGRGCR	SCF_FBXL2	908:915	Mutation rewiring degron network	0.1667
p.R912T	SIDM00775	Non-Small Cell Lung Carcinoma	GDSC	LQPGRGCR	SCF_FBXL2	908:915	Mutation altering degron motif	0.7876
p.R912T	ACH-000785	Lung Cancer	CCLE	LQPGRGCR	SCF_FBXL2	908:915	Mutation altering degron motif	0.7876
p.R912T	NCI-H2126	lung	COSMIC	LQPGRGCR	SCF_FBXL2	908:915	Mutation altering degron motif	0.7876

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*NOTE: the Kaplan plots were collected from OncoLnc