DegronMD - Q9Y6Q6(TNFRSF11A)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D191N	TCGA-A5-A2K5	UCEC	TCGA	VCSSS	DEG_SPOP_SBC_1	193:197	Mutation rewiring degron network	0.2778
p.D191N	DO41379	UCEC	ICGC	VCSSS	DEG_SPOP_SBC_1	193:197	Mutation rewiring degron network	0.2778
p.T187A	TCGA-A6-3807	COAD	TCGA	VCSSS	DEG_SPOP_SBC_1	193:197	Mutation rewiring degron network	0.1667
p.T187A	DO9034	COAD	ICGC	VCSSS	DEG_SPOP_SBC_1	193:197	Mutation rewiring degron network	0.1667
p.E188D	TCGA-EO-A22R	UCEC	TCGA	VCSSS	DEG_SPOP_SBC_1	193:197	Mutation rewiring degron network	0.1944
p.E188D	DO42713	UCEC	ICGC	VCSSS	DEG_SPOP_SBC_1	193:197	Mutation rewiring degron network	0.1944
p.E188K	TCGA-FW-A3R5	SKCM	TCGA	VCSSS	DEG_SPOP_SBC_1	193:197	Mutation rewiring degron network	0.1944
p.E188K	DO37406	SKCM	ICGC	VCSSS	DEG_SPOP_SBC_1	193:197	Mutation rewiring degron network	0.1944
p.N205H	TCGA-GN-A26C	SKCM	TCGA	VCSSS	DEG_SPOP_SBC_1	193:197	Mutation rewiring degron network	0.1111
p.N205H	DO37782	SKCM	ICGC	VCSSS	DEG_SPOP_SBC_1	193:197	Mutation rewiring degron network	0.1111
p.A192V	DO228483	BRCA	ICGC	VCSSS	DEG_SPOP_SBC_1	193:197	Mutation rewiring degron network	0.3056
p.A192V	DO229010	COCA	ICGC	VCSSS	DEG_SPOP_SBC_1	193:197	Mutation rewiring degron network	0.3056
p.A192V	DO229013	COCA	ICGC	VCSSS	DEG_SPOP_SBC_1	193:197	Mutation rewiring degron network	0.3056
p.A192V	DO229016	COCA	ICGC	VCSSS	DEG_SPOP_SBC_1	193:197	Mutation rewiring degron network	0.3056
p.A192V	DO229003	COCA	ICGC	VCSSS	DEG_SPOP_SBC_1	193:197	Mutation rewiring degron network	0.3056
p.A192V	DO229005	COCA	ICGC	VCSSS	DEG_SPOP_SBC_1	193:197	Mutation rewiring degron network	0.3056
p.A192V	DO229346	LAML	ICGC	VCSSS	DEG_SPOP_SBC_1	193:197	Mutation rewiring degron network	0.3056
p.G206V	DO43041	UCEC	ICGC	VCSSS	DEG_SPOP_SBC_1	193:197	Mutation rewiring degron network	0.0833
p.G206V	DO42793	UCEC	ICGC	VCSSS	DEG_SPOP_SBC_1	193:197	Mutation rewiring degron network	0.0833

Kaplan plot for TNFRSF11A in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

TNFRSF11A

UniProt ID: Q9Y6Q6

Entrez ID: 8792

Protein name: Tumor necrosis factor receptor superfamily member 11A (Osteoclast differentiation factor receptor) (ODFR) (Receptor activator of NF-KB) (CD antigen CD265)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for TNFRSF11A in