mutLBSgeneDB |
Gene summary for 101930112 |
![]() |
Basic gene Info. | Gene symbol | 101930112 |
Gene name | ||
Synonyms | ||
Cytomap | UCSC genome browser: | |
Type of gene | ||
RefGenes | ||
Description | ||
Modification date | ||
dbXrefs | ||
Protein | UniProt: Q9UQ90 go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_101930112 | |
BioGPS: 101930112 | ||
Pathway | NCI Pathway Interaction Database: 101930112 | |
KEGG: 101930112 | ||
REACTOME: 101930112 | ||
Pathway Commons: 101930112 | ||
Context | iHOP: 101930112 | |
ligand binding site mutation search in PubMed: 101930112 | ||
UCL Cancer Institute: 101930112 | ||
Assigned class in mutLBSgeneDB |
![]() |
GO ID | GO Term | PubMed ID |
Top |
Ligand binding site mutations for 101930112 |
![]() |
LBS | AAchange of nsSNV | Cancer type | # samples |
cf) Cancer type abbreviation. BLCA: Bladder urothelial carcinoma, BRCA: Breast invasive carcinoma, CESC: Cervical squamous cell carcinoma and endocervical adenocarcinoma, COAD: Colon adenocarcinoma, GBM: Glioblastoma multiforme, LGG: Brain lower grade glioma, HNSC: Head and neck squamous cell carcinoma, KICH: Kidney chromophobe, KIRC: Kidney renal clear cell carcinoma, KIRP: Kidney renal papillary cell carcinoma, LAML: Acute myeloid leukemia, LUAD: Lung adenocarcinoma, LUSC: Lung squamous cell carcinoma, OV: Ovarian serous cystadenocarcinoma, PAAD: Pancreatic adenocarcinoma, PRAD: Prostate adenocarcinoma, SKCM: Skin cutaneous melanoma, STAD: Stomach adenocarcinoma, THCA: Thyroid carcinoma, UCEC: Uterine corpus endometrial carcinoma. |
Top |
Protein structure related information for 101930112 |
![]() Mupro score denotes assessment of the effect of mutations on thermodynamic stability. (ΔΔE<0: mutation decreases stability, ΔΔE>0: mutation increases stability) |
![]() ![]() |
![]() |
![]() Blue: mutations of positive stability change. and red : the most recurrent mutation for this gene. |
LBS | AAchange of nsSNV | Relative stability change | A519 | A519T | -1.0632215 | A312 | G313R | -0.6129193 |
(MuPro1.1: Jianlin Cheng et al., Prediction of Protein Stability Changes for Single-Site Mutations Using Support Vector Machines, PROTEINS: Structure, Function, and Bioinformatics. 2006, 62:1125-1132) |
![]() |
Top |
Differential gene expression and gene-gene network for 101930112 |
![]() |
![]() |
Top |
Top |
Phenotype information for 101930112 |
![]() |
Disease ID | Disease name | # PubMed | Association type |
![]() |
Allele ID | AA change | Clinical significance | Origin | Phenotype IDs |
Top |
Pharmacological information for 101930112 |
![]() |
Drug status | DrugBank ID | Name | Type | Drug structure |
![]() |
![]() |
![]() |
Ligand ID | Ligand short name | Ligand long name | PDB ID | PDB name | mutLBS | ADP | ADP | 2qz4 | A | A312 A519 |
Top |
Conservation information for LBS of 101930112 |
![]() |
LBS | AA sequence | # species | Species | A312 | SFQDVAGMHEA | 2 | Mus musculus, Rattus norvegicus | A312 | SFKDVAGMHEA | 1 | Homo sapiens | A519 | PGFSGADIANI | 2 | Homo sapiens, Mus musculus | A519 | PGFS------- | 1 | Rattus norvegicus | C353 | LGPPGCGKTLL | 3 | Homo sapiens, Mus musculus, Rattus norvegicus | D310 | GVSFQDVAGMH | 2 | Mus musculus, Rattus norvegicus | D310 | GVSFKDVAGMH | 1 | Homo sapiens | G352 | LLGPPGCGKTL | 3 | Homo sapiens, Mus musculus, Rattus norvegicus | G354 | GPPGCGKTLLA | 3 | Homo sapiens, Mus musculus, Rattus norvegicus | G518 | TPGFSGADIAN | 2 | Homo sapiens, Mus musculus | G518 | TPGFS------ | 1 | Rattus norvegicus | H492 | EIFEQHLKGLK | 2 | Mus musculus, Rattus norvegicus | H492 | EIFEQHLKSLK | 1 | Homo sapiens | K355 | PPGCGKTLLAK | 3 | Homo sapiens, Mus musculus, Rattus norvegicus | L357 | GCGKTLLAKAV | 3 | Homo sapiens, Mus musculus, Rattus norvegicus | P351 | LLLGPPGCGKT | 3 | Homo sapiens, Mus musculus, Rattus norvegicus | T356 | PGCGKTLLAKA | 3 | Homo sapiens, Mus musculus, Rattus norvegicus |
![]() |
Copyright © 2016-Present - The University of Texas Health Science Center at Houston |