mutLBSgeneDB |
Gene summary for S100A16 |
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Basic gene Info. | Gene symbol | S100A16 |
Gene name | S100 calcium binding protein A16 | |
Synonyms | DT1P1A7|S100F | |
Cytomap | UCSC genome browser: 1q21 | |
Type of gene | protein-coding | |
RefGenes | NM_080388.1, | |
Description | S100 calcium-binding protein A16aging-associated gene 13 proteinaging-associated protein 13protein S100-A16protein S100-F | |
Modification date | 20141207 | |
dbXrefs | HGNC : HGNC | |
Ensembl : ENSG00000188643 | ||
HPRD : 11529 | ||
Vega : OTTHUMG00000013545 | ||
Protein | UniProt: Q96FQ6 go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_S100A16 | |
BioGPS: 140576 | ||
Pathway | NCI Pathway Interaction Database: S100A16 | |
KEGG: S100A16 | ||
REACTOME: S100A16 | ||
Pathway Commons: S100A16 | ||
Context | iHOP: S100A16 | |
ligand binding site mutation search in PubMed: S100A16 | ||
UCL Cancer Institute: S100A16 | ||
Assigned class in mutLBSgeneDB | C: This gene just belongs to mutLBSgenes. |
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GO ID | GO Term | PubMed ID |
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Ligand binding site mutations for S100A16 |
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LBS | AAchange of nsSNV | Cancer type | # samples | R73 | R73C | STAD | 1 | K32,L28 | K30N | UCEC | 1 |
cf) Cancer type abbreviation. BLCA: Bladder urothelial carcinoma, BRCA: Breast invasive carcinoma, CESC: Cervical squamous cell carcinoma and endocervical adenocarcinoma, COAD: Colon adenocarcinoma, GBM: Glioblastoma multiforme, LGG: Brain lower grade glioma, HNSC: Head and neck squamous cell carcinoma, KICH: Kidney chromophobe, KIRC: Kidney renal clear cell carcinoma, KIRP: Kidney renal papillary cell carcinoma, LAML: Acute myeloid leukemia, LUAD: Lung adenocarcinoma, LUSC: Lung squamous cell carcinoma, OV: Ovarian serous cystadenocarcinoma, PAAD: Pancreatic adenocarcinoma, PRAD: Prostate adenocarcinoma, SKCM: Skin cutaneous melanoma, STAD: Stomach adenocarcinoma, THCA: Thyroid carcinoma, UCEC: Uterine corpus endometrial carcinoma. |
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Protein structure related information for S100A16 |
![]() Mupro score denotes assessment of the effect of mutations on thermodynamic stability. (ΔΔE<0: mutation decreases stability, ΔΔE>0: mutation increases stability) |
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![]() Blue: mutations of positive stability change. and red : the most recurrent mutation for this gene. |
LBS | AAchange of nsSNV | Relative stability change | R73 | R73C | -1.1056754 | L28 | K30N | -1.0984645 | K32 | K30N | -1.0984645 |
(MuPro1.1: Jianlin Cheng et al., Prediction of Protein Stability Changes for Single-Site Mutations Using Support Vector Machines, PROTEINS: Structure, Function, and Bioinformatics. 2006, 62:1125-1132) |
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Differential gene expression and gene-gene network for S100A16 |
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Phenotype information for S100A16 |
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Disease ID | Disease name | # PubMed | Association type |
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Allele ID | AA change | Clinical significance | Origin | Phenotype IDs |
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Pharmacological information for S100A16 |
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Drug status | DrugBank ID | Name | Type | Drug structure |
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Ligand ID | Ligand short name | Ligand long name | PDB ID | PDB name | mutLBS | CA | CALCIUM(2+) | 2l51 | A | L28 K32 | CA | CALCIUM(2+) | 2l51 | A | R73 |
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Conservation information for LBS of S100A16 |
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LBS | AA sequence | # species | Species |
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