mutLBSgeneDB

mutLBSgeneDB
mutated Ligand Binding Site gene DataBase

Home

Download

 Statistics

Help

About Us
Bioinformatics and Systems Medicine Laboratory Bioinformatics and Systems Medicine Laboratory

Gene Summary

Ligand Binding Site Mutation Information

Protein Structure Related Information

Gene Expression and Gene-Gene Network

Phenotype Information

Pharmacological Information

Conservation Information for LBS

Gene summary for CYP51A1
Gene summary
Basic gene Info.Gene symbolCYP51A1
Gene namecytochrome P450, family 51, subfamily A, polypeptide 1
SynonymsCP51|CYP51|CYPL1|LDM|P450-14DM|P450L1
CytomapUCSC genome browser: 7q21.2
Type of geneprotein-coding
RefGenesNM_000786.3,
NM_001146152.1,
DescriptionCYPLIcytochrome P450 51A1cytochrome P450, 51 (lanosterol 14-alpha-demethylase)cytochrome P450-14DMcytochrome P45014DMcytochrome P450LIlanosterol 14-alpha demethylaselanosterol 14-alpha-demethylasesterol 14-alpha demethylase
Modification date20141207
dbXrefs MIM : 601637
HGNC : HGNC
Ensembl : ENSG00000001630
HPRD : 03381
Vega : OTTHUMG00000131131
ProteinUniProt: Q16850
go to UniProt's Cross Reference DB Table
ExpressionCleanEX: HS_CYP51A1
BioGPS: 1595
PathwayNCI Pathway Interaction Database: CYP51A1
KEGG: CYP51A1
REACTOME: CYP51A1
Pathway Commons: CYP51A1
ContextiHOP: CYP51A1
ligand binding site mutation search in PubMed: CYP51A1
UCL Cancer Institute: CYP51A1
Assigned class in mutLBSgeneDBB: This gene belongs to targetable_mutLBSgenes.

Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez
GO IDGO TermPubMed ID
GO:0006694steroid biosynthetic process20149798
GO:0070988demethylation20149798


Top
Ligand binding site mutations for CYP51A1

Cancer type specific mutLBS sorted by frequency
LBSAAchange of nsSNVCancer type# samples
P67Y69CCOAD2
L308G309WLUAD1
N493I494VSTAD1
M487N489TUCEC1
cf) Cancer type abbreviation. BLCA: Bladder urothelial carcinoma, BRCA: Breast invasive carcinoma, CESC: Cervical squamous cell carcinoma and endocervical adenocarcinoma, COAD: Colon adenocarcinoma, GBM: Glioblastoma multiforme, LGG: Brain lower grade glioma, HNSC: Head and neck squamous cell carcinoma, KICH: Kidney chromophobe, KIRC: Kidney renal clear cell carcinoma, KIRP: Kidney renal papillary cell carcinoma, LAML: Acute myeloid leukemia, LUAD: Lung adenocarcinoma, LUSC: Lung squamous cell carcinoma, OV: Ovarian serous cystadenocarcinoma, PAAD: Pancreatic adenocarcinoma, PRAD: Prostate adenocarcinoma, SKCM: Skin cutaneous melanoma, STAD: Stomach adenocarcinoma, THCA: Thyroid carcinoma, UCEC: Uterine corpus endometrial carcinoma.


Top
Protein structure related information for CYP51A1
Relative protein structure stability change (ΔΔE) using Mupro 1.1
Mupro score denotes assessment of the effect of mutations on thermodynamic stability.
  (ΔΔE<0: mutation decreases stability, ΔΔE>0: mutation increases stability)
: nsSNV at non-LBS: nsSNV at LBS

nsSNVs sorted by the relative stability change of protein structure by each mutation
Blue: mutations of positive stability change. and red : the most recurrent mutation for this gene.
LBSAAchange of nsSNVRelative stability change
(MuPro1.1: Jianlin Cheng et al., Prediction of Protein Stability Changes for Single-Site Mutations Using Support Vector Machines, PROTEINS: Structure, Function, and Bioinformatics. 2006, 62:1125-1132)

Structure image for CYP51A1 from PDB
PDB IDPDB titlePDB structure
3JUVCrystal structure of human lanosterol 14alpha-demethylase (CYP51)

Top
Differential gene expression and gene-gene network for CYP51A1
Differential gene expression between mutated and non-mutated LBS samples in all 16 major cancer types

Differential co-expressed gene network based on protein-protein interaction data (CePIN)
* Left PPI network was created from samples with mutations in the LBS of CYP51A1 and the right PPI network was created from samples without mutations in the LBS of CYP51A1. Only genes with p-value < 0.05 are shown.
Red circle: input gene. Orange circle: LBSgene. Blue circle: other gene.


Top

Top
Phenotype information for CYP51A1
Gene level disease information (DisGeNet)
Disease IDDisease name# PubMedAssociation type

Mutation level pathogenic information (ClinVar annotation)
Allele IDAA changeClinical significanceOriginPhenotype IDs

Top
Pharmacological information for CYP51A1

Gene-centered drug-gene interaction network
Drug information targeting mutLBSgene (Approved drugs only)
Drug statusDrugBank IDNameTypeDrug structure
Approved|vet_approvedDB00199ErythromycinSmall molecule
ApprovedDB00916MetronidazoleSmall molecule
ApprovedDB01007TioconazoleSmall molecule
ApprovedDB01045RifampicinSmall molecule
Approved|investigationalDB01167ItraconazoleSmall molecule
ExperimentalDB077051-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLESmall molecule

Gene-centered ligand-gene interaction network

Ligands binding to mutated ligand binding site of CYP51A1 go to BioLip
Ligand IDLigand short nameLigand long namePDB IDPDB namemutLBS
HEMHEME B3jusAL308
ECL1-[(2R)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE3jusAL308
HEMHEME B3jusBL308
ECL1-[(2R)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE3jusBL308
HEMHEME B3juvAL308
HEMHEME B3ld6AL308
HEMHEME B3ld6BL308
KKK(2R,4S)-KETOCONAZOLE3ld6AM487
BCDBETA-CYCLODEXTRIN3jusAN493
BCDBETA-CYCLODEXTRIN3jusBN493
BCDBETA-CYCLODEXTRIN3ld6AN493
BCDBETA-CYCLODEXTRIN3ld6BN493
BCDBETA-CYCLODEXTRIN3jusAP67


Top
Conservation information for LBS of CYP51A1
Multiple alignments for Q16850 in multiple species
LBSAA sequence# speciesSpecies
A311IGLLLAGQHTS4Homo sapiens, Bos taurus, Mus musculus, Rattus norvegicus
A311IGVLMGGQHTS2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
A311IAALFAGQHTS1Arabidopsis thaliana
A311IALLMAGQHTS1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
A455IGENFAYVQIK3Homo sapiens, Bos taurus, Rattus norvegicus
A455LGEPFAYLQIK1Arabidopsis thaliana
A455VGENFAYVQIK1Mus musculus
A455IGEQFAYMHLS1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
A455IGEHFAYCQLG1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
A455IGEGFAYMQLG1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
C449AGRHRCIGENF3Homo sapiens, Bos taurus, Rattus norvegicus
C449GGRHGCLGEPF1Arabidopsis thaliana
C449AGRHRCVGENF1Mus musculus
C449AGRHRCIGEQF1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
C449GGRHRCIGEHF1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
C449GGRHRCIGEGF1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
F105MVGKTFTYLLG4Homo sapiens, Bos taurus, Mus musculus, Rattus norvegicus
F105LLGRVMTVYLG2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
F105LVHKKITFLIG1Arabidopsis thaliana
F105CMGRKMTAFLG1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
F139LTTPVFGKGVA4Homo sapiens, Bos taurus, Mus musculus, Rattus norvegicus
F139FNVPTFGPGVV1Arabidopsis thaliana
F139LTTPVFGKDVV1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
F139LTTPVFGKGVI1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
F139LTTPVFGEGVV1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
F152VPNPVFLEQKK1Homo sapiens
F152VDYSVRQEQFR1Arabidopsis thaliana
F152VPNTVFLEQKK1Bos taurus
F152VPNAIFLEQKK1Mus musculus
F152VPNAVFLEQKK1Rattus norvegicus
F152IPNHVFMEHKK1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
F152CPNSRLMEQKK1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
F152CPNHRLMEQKK1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
F234DLDGGFSHAAW3Homo sapiens, Bos taurus, Rattus norvegicus
F234DLDNGMLPISV1Arabidopsis thaliana
F234DLDGGFTHAAW1Mus musculus
F234DLDQGFSPVNF1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
F234DLDKGFTPINF1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
F234DLDKGFTPLNF1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
F442--YVPFGAGRH4Homo sapiens, Bos taurus, Mus musculus, Rattus norvegicus
F442SPYLPFGGGRH2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
F442--YIAFGGGRH1Arabidopsis thaliana
F442SPYLPFGAGRH1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
F454CIGENFAYVQI3Homo sapiens, Bos taurus, Rattus norvegicus
F454CLGEPFAYLQI1Arabidopsis thaliana
F454CVGENFAYVQI1Mus musculus
F454CIGEQFAYMHL1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
F454CIGEHFAYCQL1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
F454CIGEGFAYMQL1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
F65-PPYIFSPIPF1Homo sapiens
F65LPPTLKAWPPL1Arabidopsis thaliana
F65-PPYIVSPIPF1Bos taurus
F65-PPHIYSPIPF1Mus musculus
F65-PPYIYSPIPF1Rattus norvegicus
F65RPPIVFHWIPF1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
F65RPPLVFYWIPW1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
F65RVPLVPFMVPW1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
G307AGMLIGLLLAG3Homo sapiens, Bos taurus, Rattus norvegicus
G307ANLLIGVLMGG2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
G307TGLLIAALFAG1Arabidopsis thaliana
G307SGMLIGLLLAG1Mus musculus
G307AGMMIALLMAG1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
G312GLLLAGQHTSS4Homo sapiens, Bos taurus, Mus musculus, Rattus norvegicus
G312GVLMGGQHTSA2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
G312AALFAGQHTSS1Arabidopsis thaliana
G312ALLMAGQHTSA1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
G443-YVPFGAGRHR4Homo sapiens, Bos taurus, Mus musculus, Rattus norvegicus
G443PYLPFGGGRHR2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
G443-YIAFGGGRHG1Arabidopsis thaliana
G443PYLPFGAGRHR1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
G451RHRCIGENFAY3Homo sapiens, Bos taurus, Rattus norvegicus
G451RHGCLGEPFAY1Arabidopsis thaliana
G451RHRCVGENFAY1Mus musculus
G451RHRCIGEQFAY1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
G451RHRCIGEHFAY1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
G451RHRCIGEGFAY1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
H447FGAGRHRCIGE4Homo sapiens, Bos taurus, Rattus norvegicus, Schizosaccharomyces pombe (strain 972 / ATCC 24843)
H447FGGGRHRCIGE2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
H447FGGGRHGCLGE1Arabidopsis thaliana
H447FGAGRHRCVGE1Mus musculus
I377RLRPPIMTMMR3Bos taurus, Mus musculus, Rattus norvegicus
I377RMHHPLHSLFR2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
I377RLRPPIMIMMR1Homo sapiens
I377RLHPPLIMLMR1Arabidopsis thaliana
I377RLHPPIHSHMR1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
I379RPPIMTMMRMA2Mus musculus, Rattus norvegicus
I379HHPLHSLFRKV2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
I379RPPIMIMMRMA1Homo sapiens
I379HPPLIMLMRAS1Arabidopsis thaliana
I379RPPIMTMMRLA1Bos taurus
I379HPPIHSHMRKV1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
I450GRHRCIGENFA3Homo sapiens, Bos taurus, Rattus norvegicus
I450GRHGCLGEPFA1Arabidopsis thaliana
I450GRHRCVGENFA1Mus musculus
I450GRHRCIGEQFA1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
I450GRHRCIGEHFA1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
I450GRHRCIGEGFA1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
I64--PPYIFSPIP1Homo sapiens
I64RLPPTLKAWPP1Arabidopsis thaliana
I64--PPYIVSPIP1Bos taurus
I64--PPHIYSPIP1Mus musculus
I64--PPYIYSPIP1Rattus norvegicus
I64KRPPIVFHWIP1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
I64DRPPLVFYWIP1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
I64DRVPLVPFMVP1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
K156VFLEQKKMLKS2Homo sapiens, Bos taurus
K156VRQEQFRFFTE1Arabidopsis thaliana
K156IFLEQKKIIKS1Mus musculus
K156VFLEQKKILKS1Rattus norvegicus
K156VFMEHKKFIKS1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
K156RLMEQKKFVKG1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
K156RLMEQKKFCKN1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
L134EVYGRLTTPVF2Mus musculus, Rattus norvegicus
L134DVYSRLTTPVF1Homo sapiens
L134EVY-QFNVPTF1Arabidopsis thaliana
L134EVYSRLTTPVF1Bos taurus
L134EAYSHLTTPVF1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
L134AAYAHLTTPVF1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
L134EAYTKLTTPVF1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
L163MLKSGLNIAHF2Homo sapiens, Bos taurus
L163FFTEALRVNKL1Arabidopsis thaliana
L163IIKSGLNIAHF1Mus musculus
L163ILKSGLNIAHF1Rattus norvegicus
L163FIKSGLGFSQF1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
L163FVKGALTKEAF1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
L163FCKNALSTEAF1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
L308GMLIGLLLAGQ4Homo sapiens, Bos taurus, Mus musculus, Rattus norvegicus
L308NLLIGVLMGGQ2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
L308GLLIAALFAGQ1Arabidopsis thaliana
L308GMMIALLMAGQ1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
L371CIKETLRLRPP4Homo sapiens, Bos taurus, Mus musculus, Rattus norvegicus
L371CIKEALRLHPP1Arabidopsis thaliana
L371VIQETLRLHPP1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
L371TIKETLRMHHP1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
L371VIKETLRMHHP1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
M380PPIMTMMRMAK2Mus musculus, Rattus norvegicus
M380PPIMIMMRMAR1Homo sapiens
M380PPLIMLMRASH1Arabidopsis thaliana
M380PPIMTMMRLAK1Bos taurus
M380PPIHSHMRKVK1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
M380HPLHSLFRKVM1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
M380HPLHSLFRKVT1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
M381PIMTMMRMAKT2Mus musculus, Rattus norvegicus
M381PIMIMMRMART1Homo sapiens
M381PLIMLMRASHS1Arabidopsis thaliana
M381PIMTMMRLAKT1Bos taurus
M381PIHSHMRKVKR1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
M381PLHSLFRKVMK1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
M381PLHSLFRKVTR1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
M487VNYTTMIHTPE4Homo sapiens, Bos taurus, Mus musculus, Rattus norvegicus
M487IDWNAMVVGVK1Arabidopsis thaliana
M487VDYSSMVALPL1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
M487PDFTSMVTLPT1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
M487PDFTSMVTLPS1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
N493IHTPENPV-IR3Homo sapiens, Mus musculus, Rattus norvegicus
N493VVGVKGNVMVR1Arabidopsis thaliana
N493IHTPEKPI-IR1Bos taurus
N493VALPLGPVKIA1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N493VTLPTGPAKII1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N493VTLPSEPCRIA1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
P137SRLTTPVFGKG2Homo sapiens, Bos taurus
P137GRLTTPVFGKG2Mus musculus, Rattus norvegicus
P137-QFNVPTFGPG1Arabidopsis thaliana
P137SHLTTPVFGKD1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P137AHLTTPVFGKG1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P137TKLTTPVFGEG1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
P376LRLRPPIMTMM3Bos taurus, Mus musculus, Rattus norvegicus
P376LRMHHPLHSLF2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
P376LRLRPPIMIMM1Homo sapiens
P376LRLHPPLIMLM1Arabidopsis thaliana
P376LRLHPPIHSHM1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P441---YVPFGAGR4Homo sapiens, Bos taurus, Mus musculus, Rattus norvegicus
P441SSPYLPFGGGR2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
P441---YIAFGGGR1Arabidopsis thaliana
P441ASPYLPFGAGR1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P61VKS--PPYIFS1Homo sapiens
P61KKKRLPPTLKA1Arabidopsis thaliana
P61AKS--PPYIVS1Bos taurus
P61AKS--PPHIYS1Mus musculus
P61AKS--PPYIYS1Rattus norvegicus
P61RNSKRPPIVFH1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P61LRKDRPPLVFY1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P61FRKDRVPLVPF1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
P62KS--PPYIFSP1Homo sapiens
P62KKRLPPTLKAW1Arabidopsis thaliana
P62KS--PPYIVSP1Bos taurus
P62KS--PPHIYSP1Mus musculus
P62KS--PPYIYSP1Rattus norvegicus
P62NSKRPPIVFHW1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P62RKDRPPLVFYW1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P62RKDRVPLVPFM1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
P67PYIFSPIPFLG1Homo sapiens
P67PTLKAWPPLVG1Arabidopsis thaliana
P67PYIVSPIPFLG1Bos taurus
P67PHIYSPIPFLG1Mus musculus
P67PYIYSPIPFLG1Rattus norvegicus
P67PIVFHWIPFVG1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P67PLVFYWIPWVG1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P67PLVPFMVPWVG1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
R382IMTMMRMAKTP2Mus musculus, Rattus norvegicus
R382IMIMMRMARTP1Homo sapiens
R382LIMLMRASHSD1Arabidopsis thaliana
R382IMTMMRLAKTP1Bos taurus
R382IHSHMRKVKRD1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R382LHSLFRKVMKD1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
R382LHSLFRKVTRD1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
R448GAGRHRCIGEN3Homo sapiens, Bos taurus, Rattus norvegicus
R448GGGRHGCLGEP1Arabidopsis thaliana
R448GAGRHRCVGEN1Mus musculus
R448GAGRHRCIGEQ1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R448GGGRHRCIGEH1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
R448GGGRHRCIGEG1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
S316AGQHTSSTTSA4Homo sapiens, Bos taurus, Mus musculus, Rattus norvegicus
S316GGQHTSAATSA2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
S316AGQHTSSITST1Arabidopsis thaliana
S316AGQHTSAATIV1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
S66PPYIFSPIPFL1Homo sapiens
S66PPTLKAWPPLV1Arabidopsis thaliana
S66PPYIVSPIPFL1Bos taurus
S66PPHIYSPIPFL1Mus musculus
S66PPYIYSPIPFL1Rattus norvegicus
S66PPIVFHWIPFV1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
S66PPLVFYWIPWV1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
S66VPLVPFMVPWV1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
T135VYSRLTTPVFG2Homo sapiens, Bos taurus
T135VYGRLTTPVFG2Mus musculus, Rattus norvegicus
T135VY-QFNVPTFG1Arabidopsis thaliana
T135AYSHLTTPVFG1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
T135AYAHLTTPVFG1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
T135AYTKLTTPVFG1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
T315LAGQHTSSTTS4Homo sapiens, Bos taurus, Mus musculus, Rattus norvegicus
T315MGGQHTSAATS2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
T315FAGQHTSSITS1Arabidopsis thaliana
T315MAGQHTSAATI1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
W239FSHAAWLLPGW3Homo sapiens, Bos taurus, Rattus norvegicus
W239MLPISVLFP-Y1Arabidopsis thaliana
W239FTHAAWLLPAW1Mus musculus
W239FSPVNFVFP-W1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
W239FTPINFVFP-N1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
W239FTPLNFVFR-D1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Y131NAEEVYGRLTT2Mus musculus, Rattus norvegicus
Y131NAEDVYSRLTT1Homo sapiens
Y131SQQEVY-QFNV1Arabidopsis thaliana
Y131NAEEVYSRLTT1Bos taurus
Y131NAEEAYSHLTT1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y131SAEAAYAHLTT1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y131SAEEAYTKLTT1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Y145GKGVAYDVPNA2Mus musculus, Rattus norvegicus
Y145GKGVAYDVPNP1Homo sapiens
Y145GPGVVFDVDYS1Arabidopsis thaliana
Y145GKGVAYDVPNT1Bos taurus
Y145GKDVVYDIPNH1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y145GKGVIYDCPNS1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y145GEGVVYDCPNH1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Y478-IDG-YFPTVN2Homo sapiens, Bos taurus
Y478-VSP--FPEID1Arabidopsis thaliana
Y478-ING-YFPTVN1Mus musculus
Y478-ING-YFPSVN1Rattus norvegicus
Y478-IGK--VPNVD1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y478-PEGKTVPPPD1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y478DMKG--VPNPD1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Y63S--PPYIFSPI1Homo sapiens
Y63KRLPPTLKAWP1Arabidopsis thaliana
Y63S--PPYIVSPI1Bos taurus
Y63S--PPHIYSPI1Mus musculus
Y63S--PPYIYSPI1Rattus norvegicus
Y63SKRPPIVFHWI1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y63KDRPPLVFYWI1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y63KDRVPLVPFMV1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Y92NAYEKYGPVFS3Homo sapiens, Mus musculus, Rattus norvegicus
Y92EEYPKLGSVFT1Arabidopsis thaliana
Y92DAYEKYGPVFS1Bos taurus
Y92ECRAKYGDVFT1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y92ECQKKYGDIFS1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y92KCQQKYGDVFA1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)


Copyright © 2016-Present - The University of Texas Health Science Center at Houston
Site Policies | State of Texas