mutLBSgeneDB

mutLBSgeneDB
mutated Ligand Binding Site gene DataBase

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Gene Summary

Ligand Binding Site Mutation Information

Protein Structure Related Information

Gene Expression and Gene-Gene Network

Phenotype Information

Pharmacological Information

Conservation Information for LBS

Gene summary for HSP90AA1
Gene summary
Basic gene Info.Gene symbolHSP90AA1
Gene nameheat shock protein 90kDa alpha (cytosolic), class A member 1
SynonymsEL52|HSP86|HSP89A|HSP90A|HSP90N|HSPC1|HSPCA|HSPCAL1|HSPCAL4|HSPN|Hsp89|Hsp90|LAP-2|LAP2
CytomapUCSC genome browser: 14q32.33
Type of geneprotein-coding
RefGenesNM_001017963.2,
NM_005348.3,
DescriptionHSP 86LPS-associated protein 2epididymis luminal secretory protein 52heat shock 86 kDaheat shock 90kD protein 1, alphaheat shock 90kD protein 1, alpha-like 4heat shock 90kD protein, alpha-like 4heat shock 90kDa protein 1, alphaheat shock protein H
Modification date20141222
dbXrefs MIM : 140571
HGNC : HGNC
Ensembl : ENSG00000080824
HPRD : 00777
Vega : OTTHUMG00000171752
ProteinUniProt: P07900
go to UniProt's Cross Reference DB Table
ExpressionCleanEX: HS_HSP90AA1
BioGPS: 3320
PathwayNCI Pathway Interaction Database: HSP90AA1
KEGG: HSP90AA1
REACTOME: HSP90AA1
Pathway Commons: HSP90AA1
ContextiHOP: HSP90AA1
ligand binding site mutation search in PubMed: HSP90AA1
UCL Cancer Institute: HSP90AA1
Assigned class in mutLBSgeneDBC: This gene just belongs to mutLBSgenes.

Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez
GO IDGO TermPubMed ID
GO:0006200ATP catabolic process15937123
GO:0045040protein import into mitochondrial outer membrane15644312
GO:0051131chaperone-mediated protein complex assembly15644312


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Ligand binding site mutations for HSP90AA1

Cancer type specific mutLBS sorted by frequency
LBSAAchange of nsSNVCancer type# samples
A21A21SGBM1
Y139S140FHNSC1
M98T99AHNSC1
A21T19SLUAD1
K58K58TOV1
D86D86YSTAD1
R87,I91L89RSTAD1
cf) Cancer type abbreviation. BLCA: Bladder urothelial carcinoma, BRCA: Breast invasive carcinoma, CESC: Cervical squamous cell carcinoma and endocervical adenocarcinoma, COAD: Colon adenocarcinoma, GBM: Glioblastoma multiforme, LGG: Brain lower grade glioma, HNSC: Head and neck squamous cell carcinoma, KICH: Kidney chromophobe, KIRC: Kidney renal clear cell carcinoma, KIRP: Kidney renal papillary cell carcinoma, LAML: Acute myeloid leukemia, LUAD: Lung adenocarcinoma, LUSC: Lung squamous cell carcinoma, OV: Ovarian serous cystadenocarcinoma, PAAD: Pancreatic adenocarcinoma, PRAD: Prostate adenocarcinoma, SKCM: Skin cutaneous melanoma, STAD: Stomach adenocarcinoma, THCA: Thyroid carcinoma, UCEC: Uterine corpus endometrial carcinoma.


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Protein structure related information for HSP90AA1
Relative protein structure stability change (ΔΔE) using Mupro 1.1
Mupro score denotes assessment of the effect of mutations on thermodynamic stability.
  (ΔΔE<0: mutation decreases stability, ΔΔE>0: mutation increases stability)
: nsSNV at non-LBS: nsSNV at LBS

nsSNVs sorted by the relative stability change of protein structure by each mutation
Blue: mutations of positive stability change. and red : the most recurrent mutation for this gene.
LBSAAchange of nsSNVRelative stability change
Y139S140F0.079560229
A21T19S-1.1195776
I91L89R-1.107931
R87L89R-1.107931
A21A21S-1.0229227
M98T99A-0.96674408
K58K58T-0.6109787
D86D86Y-0.59203639
(MuPro1.1: Jianlin Cheng et al., Prediction of Protein Stability Changes for Single-Site Mutations Using Support Vector Machines, PROTEINS: Structure, Function, and Bioinformatics. 2006, 62:1125-1132)

Structure image for HSP90AA1 from PDB

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Differential gene expression and gene-gene network for HSP90AA1
Differential gene expression between mutated and non-mutated LBS samples in all 16 major cancer types

Differential co-expressed gene network based on protein-protein interaction data (CePIN)
* Left PPI network was created from samples with mutations in the LBS of HSP90AA1 and the right PPI network was created from samples without mutations in the LBS of HSP90AA1. Only genes with p-value < 0.05 are shown.
Red circle: input gene. Orange circle: LBSgene. Blue circle: other gene.


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Phenotype information for HSP90AA1
Gene level disease information (DisGeNet)
Disease IDDisease name# PubMedAssociation type
umls:C0027627Neoplasm Metastasis12Biomarker
umls:C1458155Breast Neoplasms7Biomarker
umls:C0019693HIV Infections4Biomarker
umls:C0206180Lymphoma, Large-Cell, Anaplastic3Biomarker

Mutation level pathogenic information (ClinVar annotation)
Allele IDAA changeClinical significanceOriginPhenotype IDs

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Pharmacological information for HSP90AA1
Gene expression profile of anticancer drug treated cell-lines (CCLE)
Heatmap showing the correlation between gene expression and drug response across all the cell-lines. We chose the top 20 among 138 drugs.We used Pearson's correlation coefficient.

Gene-centered drug-gene interaction network
Drug information targeting mutLBSgene (Approved drugs only)
Drug statusDrugBank IDNameTypeDrug structure
ApprovedDB00615RifabutinSmall molecule
ApprovedDB00716NedocromilSmall molecule
ExperimentalDB023599-Butyl-8-(2,5-Dimethoxy-Benzyl)-9h-Purin-6-YlamineSmall molecule
ExperimentalDB02424GeldanamycinSmall molecule
ExperimentalDB025508-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-2-Fluoro-9-Pent-4-Ylnyl-9h-Purin-6-YlamineSmall molecule
ExperimentalDB027549-Butyl-8-(3,4,5-Trimethoxybenzyl)-9h-Purin-6-AmineSmall molecule
ExperimentalDB028404-(1,3-Benzodioxol-5-Yl)-5-(5-Ethyl-2,4-Dihydroxyphenyl)-2h-Pyrazole-3-Carboxylic AcidSmall molecule
ExperimentalDB0308017-DmagSmall molecule
ExperimentalDB030938-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-YlamineSmall molecule
ExperimentalDB031378-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9-Pent-9h-Purin-6-YlamineSmall molecule
ExperimentalDB035049-Butyl-8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9h-Purin-6-YlamineSmall molecule
ExperimentalDB037494-(1h-Imidazol-4-Yl)-3-(5-Ethyl-2,4-Dihydroxy-Phenyl)-1h-PyrazoleSmall molecule
ExperimentalDB038099-Butyl-8-(3-Methoxybenzyl)-9h-Purin-6-AmineSmall molecule
ExperimentalDB038999-Butyl-8-(4-Methoxybenzyl)-9h-Purin-6-AmineSmall molecule
ExperimentalDB040549-Butyl-8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-YlamineSmall molecule
ExperimentalDB042548-Benzo[1,3]Dioxol-,5-Ylmethyl-9-Butyl-2-Fluoro-9h-Purin-6-YlamineSmall molecule
ExperimentalDB045058-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9-Pent-4-Ylnyl-9h-Purin-6-YlamineSmall molecule
ExperimentalDB04588N-[4-(AMINOSULFONYL)BENZYL]-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDESmall molecule
InvestigationalDB05134CNF1010Small molecule
InvestigationalDB06070SNX-5422Small molecule
ExperimentalDB06956N-(4-ACETYLPHENYL)-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDESmall molecule
ExperimentalDB069574-CHLORO-6-(4-{4-[4-(METHYLSULFONYL)BENZYL]PIPERAZIN-1-YL}-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOLSmall molecule
ExperimentalDB069585-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDESmall molecule
ExperimentalDB069615-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]isoxazole-3-carboxamideSmall molecule
ExperimentalDB069645-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)ISOXAZOLE-3-CARBOXAMIDESmall molecule
ExperimentalDB069692-amino-4-[2,4-dichloro-5-(2-pyrrolidin-1-ylethoxy)phenyl]-N-ethylthieno[2,3-d]pyrimidine-6-carboxamideSmall molecule
ExperimentalDB071004-CHLORO-6-(4-PIPERAZIN-1-YL-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOLSmall molecule
ExperimentalDB07317(3E)-3-[(phenylamino)methylidene]dihydrofuran-2(3H)-oneSmall molecule
ExperimentalDB073196-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINESmall molecule
ExperimentalDB073243-({2-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)ETHYNYL]BENZYL}AMINO)-1,3-OXAZOL-2(3H)-ONESmall molecule
ExperimentalDB07325N-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)METHYL]-3-{[(E)-(2-OXODIHYDROFURAN-3(2H)-YLIDENE)METHYL]AMINO}BENZENESULFONAMIDESmall molecule
ExperimentalDB074955-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)-1H-PYRAZOLE-3-CARBOXAMIDESmall molecule
ExperimentalDB075024-bromo-6-(6-hydroxy-1,2-benzisoxazol-3-yl)benzene-1,3-diolSmall molecule
ExperimentalDB075944-[4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-METHYL-1H-PYRAZOL-5-YL]-6-ETHYLBENZENE-1,3-DIOLSmall molecule
ExperimentalDB076014-chloro-6-{5-[(2-morpholin-4-ylethyl)amino]-1,2-benzisoxazol-3-yl}benzene-1,3-diolSmall molecule
ExperimentalDB078778-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINESmall molecule
ExperimentalDB081944-methyl-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-amineSmall molecule
ExperimentalDB08197(5E,7S)-2-amino-7-(4-fluoro-2-pyridin-3-ylphenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one oximeSmall molecule
ExperimentalDB084368-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H-Small molecule
ExperimentalDB084424-{[(2R)-2-(2-methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diolSmall molecule
ExperimentalDB084432-(1H-pyrrol-1-ylcarbonyl)benzene-1,3,5-triolSmall molecule
ExperimentalDB085572-[(2-methoxyethyl)amino]-4-(4-oxo-1,2,3,4-tetrahydro-9H-carbazol-9-yl)benzamideSmall molecule
ExperimentalDB087864-(2-methoxyethoxy)-6-methylpyrimidin-2-amineSmall molecule
ExperimentalDB087874-(2,4-dichlorophenyl)-5-phenyldiazenyl-pyrimidin-2-amineSmall molecule
ExperimentalDB087883,6-DIAMINO-5-CYANO-4-(4-ETHOXYPHENYL)THIENO[2,3-B]PYRIDINE-2-CARBOXAMIDESmall molecule
ExperimentalDB087892-AMINO-4-(2,4-DICHLOROPHENYL)-N-ETHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXAMIDESmall molecule

Gene-centered ligand-gene interaction network

Ligands binding to mutated ligand binding site of HSP90AA1 go to BioLip
Ligand IDLigand short nameLigand long namePDB IDPDB namemutLBS
99B5-[(2R)-BUTAN-2-YLAMINO]-N-{(3-ENDO)-8-[5- (CYCLOPROPYLCARBONYL)PYRIDIN-2-YL]-8- AZABICYCLO[3.2.1]OCT-3-YL}-2-METHYLBENZENE-1,4- DICARBOXAMIDE4awoBA21 K58 M98 Y139
99B5-[(2R)-BUTAN-2-YLAMINO]-N-{(3-ENDO)-8-[5- (CYCLOPROPYLCARBONYL)PYRIDIN-2-YL]-8- AZABICYCLO[3.2.1]OCT-3-YL}-2-METHYLBENZENE-1,4- DICARBOXAMIDE4awoAA21 M98 Y139
99AN-{(3-ENDO)-8-[5-(BENZYLCARBAMOYL)PYRIDIN-2- YL]-8-AZABICYCLO[3.2.1]OCT-3-YL}-2,5- DIMETHYLBENZENE-1,4-DICARBOXAMIDE4awpAA21 M98 Y139
99AN-{(3-ENDO)-8-[5-(BENZYLCARBAMOYL)PYRIDIN-2- YL]-8-AZABICYCLO[3.2.1]OCT-3-YL}-2,5- DIMETHYLBENZENE-1,4-DICARBOXAMIDE4awpBA21 M98 Y139
592N-BENZYL-6-[(3-ENDO)-3-{[(3-METHOXY-2- METHYLPHENYL)CARBONYL]AMINO}-8-AZABICYCLO[3.2.1]OCT- 8-YL]PYRIDINE-3-CARBOXAMIDE4awqAA21 M98 Y139
592N-BENZYL-6-[(3-ENDO)-3-{[(3-METHOXY-2- METHYLPHENYL)CARBONYL]AMINO}-8-AZABICYCLO[3.2.1]OCT- 8-YL]PYRIDINE-3-CARBOXAMIDE4awqBA21 M98 Y139
MGMAGNESIUM(2+)2uwdAD86 R87
XJG1,3-DIHYDROISOINDOL-2-YL-(2-HYDROXY-4-METHOXY-5-PROPAN-2-YL-PHENYL)METHANONE2xjgAK58 I91 M98
KOS17-DESMETHOXY-17-N,N-DIMETHYLAMINOETHYLAMINO-GELDANAMYCIN1osfAK58 M98
4BC4-(1,3-BENZODIOXOL-5-YL)-5-(5-ETHYL-2,4-DIHYDROXYPHENYL)-2H-PYRAZOLE-3-CARBOXYLIC ACID1yc1AK58 M98
4BC4-(1,3-BENZODIOXOL-5-YL)-5-(5-ETHYL-2,4-DIHYDROXYPHENYL)-2H-PYRAZOLE-3-CARBOXYLIC ACID1yc3AK58 M98
43P4-(1H-IMIDAZOL-4-YL)-3-(5-ETHYL-2,4-DIHYDROXY-PHENYL)-1H-PYRAZOLE1yc4AK58 M98
GDMGELDANAMYCIN1yetAK58 M98
BSM5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)-1H-PYRAZOLE-3-CARBOXAMIDE2bsmAK58 M98
CT5CCT0181592bt0AK58 M98
2DDN-[4-(AMINOSULFONYL)BENZYL]-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE2byiAK58 M98
AB42,5-DICHLORO-N-[4-HYDROXY-3-(2-HYDROXY-1-NAPHTHYL)PHENYL]BENZENESULFONAMIDE2bz5AK58 M98
AB42,5-DICHLORO-N-[4-HYDROXY-3-(2-HYDROXY-1-NAPHTHYL)PHENYL]BENZENESULFONAMIDE2bz5BK58 M98
2E15-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDE2cctAK58 M98
DZ82-FLUORO-8-[(6-IODO-1,3-BENZODIOXOL-5-YL)METHYL]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE2h55AK58 M98
2GG5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)ISOXAZOLE-3-CARBOXAMIDE2uwdAK58 M98
2GJ5-[2,4-DIHYDROXY-5-(1-METHYLETHYL)PHENYL]-N-ETHYL-4-[4-(MORPHOLIN-4-YLMETHYL)PHENYL]ISOXAZOLE-3-CARBOXAMIDE2vciAK58 M98
C0Y(3-TERT-BUTYL-4-HYDROXYPHENYL)MORPHOLIN-4-YL-METHANONE2xhtAK58 M98
L811,3-DIHYDROISOINDOL-2-YL-(6-HYDROXY-3,3-DIMETHYL-1,2-DIHYDROINDOL-5-YL)METHANONE2xjjAK58 M98
L811,3-DIHYDROISOINDOL-2-YL-(6-HYDROXY-3,3-DIMETHYL-1,2-DIHYDROINDOL-5-YL)METHANONE2xjjBK58 M98
VXXMETHYL VANILLATE2ye3AK58 M98
2D4N-[4-HYDROXY-3-(2-HYDROXYNAPHTHALEN-1-YL)PHENYL]THIOPHENE-2-SULFONAMIDE2ye9AK58 M98
2A93-HYDROXY-4-METHOXYBENZYL ALCOHOL2yeaAK58 M98
YI04-CHLORO-6-[5-(4-METHOXYPHENYL)-1,2,3-THIADIAZOL-4-YL]BENZENE-1,3-DIOL2yi0AK58 M98
YJW4-(5-METHYL-4-PHENYLISOXAZOL-3-YL)BENZENE-1,3-DIOL2yjwAK58 M98
B2J4-(ETHYLTHIO)-6-METHYL-1,3,5-TRIAZIN-2-AMINE3b24AK58 M98
BXZ4-BROMO-6-(6-HYDROXY-1,2-BENZISOXAZOL-3-YL)BENZENE-1,3-DIOL3bm9AK58 M98
CXZ4-CHLORO-6-{5-[(2-MORPHOLIN-4-YLETHYL)AMINO]-1,2-BENZISOXAZOL-3-YL}BENZENE-1,3-DIOL3bmyAK58 M98
PYU2-(1H-PYRROL-1-YLCARBONYL)BENZENE-1,3,5-TRIOL3ekoAK58 M98
PYU2-(1H-PYRROL-1-YLCARBONYL)BENZENE-1,3,5-TRIOL3ekoBK58 M98
PY94-{[(2R)-2-(2-METHYLPHENYL)PYRROLIDIN-1-YL]CARBONYL}BENZENE-1,3-DIOL3ekrAK58 M98
PY94-{[(2R)-2-(2-METHYLPHENYL)PYRROLIDIN-1-YL]CARBONYL}BENZENE-1,3-DIOL3ekrBK58 M98
819ETHYL (4-{3-[2,4-DIHYDROXY-5-(1-METHYLETHYL)PHENYL]-5-SULFANYL-4H-1,2,4-TRIAZOL-4-YL}BENZYL)CARBAMATE3hhuAK58 M98
819ETHYL (4-{3-[2,4-DIHYDROXY-5-(1-METHYLETHYL)PHENYL]-5-SULFANYL-4H-1,2,4-TRIAZOL-4-YL}BENZYL)CARBAMATE3hhuBK58 M98
4CD4-CHLORO-6-{[(2R)-2-(2-METHYLPHENYL)PYRROLIDIN-1-YL]CARBONYL}BENZENE-1,3-DIOL3k97AK58 M98
1RC(1R)-2-(5-CHLORO-2,4-DIHYDROXYBENZOYL)-N-ETHYLISOINDOLINE-1-CARBOXAMIDE3k98AK58 M98
1RC(1R)-2-(5-CHLORO-2,4-DIHYDROXYBENZOYL)-N-ETHYLISOINDOLINE-1-CARBOXAMIDE3k98BK58 M98
PFT4-(1,3-DIHYDRO-2H-ISOINDOL-2-YLCARBONYL)BENZENE-1,3-DIOL3k99BK58 M98
PFT4-(1,3-DIHYDRO-2H-ISOINDOL-2-YLCARBONYL)BENZENE-1,3-DIOL3k99CK58 M98
BSM5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)-1H-PYRAZOLE-3-CARBOXAMIDE3owbAK58 M98
FU54-[2-CHLORO-6-(4,4,4-TRIFLUOROBUTOXY)PHENYL]-6-METHYLPYRIMIDIN-2-AMINE3r4nBK58 M98
TUH5-[2,4-DIHYDROXY-5-(PROPAN-2-YL)PHENYL]-4-(1-METHYL-1H- INDOL-5-YL)-2,4-DIHYDRO-3H-1,2,4-TRIAZOL-3-ONE3tuhAK58 M98
TUH5-[2,4-DIHYDROXY-5-(PROPAN-2-YL)PHENYL]-4-(1-METHYL-1H- INDOL-5-YL)-2,4-DIHYDRO-3H-1,2,4-TRIAZOL-3-ONE3tuhBK58 M98
VHC4-AMINO-20,22-DIMETHYL-13-OXA-7-THIA-3,5,17- TRIAZATETRACYCLO[17.3.1.1~2,6~.1~8,12~]PENTACOSA- 1(23),2(25),3,5,8(24),9,11,19,21-NONAEN-18-ONE3vhcAK58 M98
VHE4-AMINO-18,20-DIMETHYL-7-THIA-3,5,11,15- TETRAAZATRICYCLO[15.3.1.1(2,6)]DOCOSA-1(20),2,4,6(22), 17(21),18-HEXAENE-10,16-DIONE3vhdAK58 M98
VHE4-AMINO-18,20-DIMETHYL-7-THIA-3,5,11,15- TETRAAZATRICYCLO[15.3.1.1(2,6)]DOCOSA-1(20),2,4,6(22), 17(21),18-HEXAENE-10,16-DIONE3vhdBK58 M98
HH63-(4-HYDROXYPHENYL)-1H-INDAZOL-6-OL4eehAK58 M98
0OY(4-HYDROXYPHENYL)(MORPHOLIN-4-YL)METHANONE4eghAK58 M98
RDCRADICICOL4egkAK58 M98
VJ6VALERJESOMYCIN(4E,8S,9S,10E,12S,13R,14S)-13,14,20-TRIMETHOXY-4,10,12- TRIMETHYL-3-OXO-16-OXA-2-AZABICYCLO[16.3.1]DOCOSA- 1(22),4,10,18,20-PENTAENE-8,9-DIYL DICARBAMATE4jqlAK58 M98
9UN5-[2,4-DIHYDROXY-6-(4-NITROPHENOXY)PHENYL]-N- (1-METHYLPIPERIDIN-4-YL)-1,2-OXAZOLE-3- CARBOXAMIDE4b7pAK58 M98
XKL5-[2,4-DIHYDROXY-6-(4-NITROPHENOXY)PHENYL]-N- ETHYL-1,2-OXAZOLE-3-CARBOXAMIDE4bqjAK58 M98
RL1[5-(6-BROMO[1,2,4]TRIAZOLO[4,3-A]PYRIDIN-3-YL)-2,4- DIHYDROXYPHENYL](3,4-DIHYDROISOQUINOLIN-2(1H)-YL) METHANONE4l8zAK58 M98
S46(4-HYDROXYPHENYL)(4-METHYLPIPERAZIN-1-YL)METHANONE4l94AK58 M98
W2D2-AMINO-5-(1,3-BENZODIOXOL-5-YLMETHYL)[1,2,4] TRIAZOLO[1,5-C]QUINAZOLINE-8-SULFONAMIDE4cwqAK58 M98
G3R2-AMINO-5-(1,3-BENZODIOXOL-5-YLMETHYL)-8-[(2- HYDROXYETHYL)AMINO]-1H-[1,2,4]TRIAZOLO[1,5-C] QUINAZOLIN-4-IUM4cwsAK58 M98
FJ2N-[3-(5-CHLORO-2,4-DIHYDROXYPHENYL)-4-(4- METHOXYPHENYL)-1,2-OXAZOL-5-YL]ACETAMIDE4lweAK58 M98
FJ5N-{3-[2,4-DIHYDROXY-5-(PROPAN-2-YL)PHENYL]-4-[4- (MORPHOLIN-4-YLMETHYL)PHENYL]-1,2-OXAZOL-5- YL}CYCLOPROPANECARBOXAMIDE4lwhAK58 M98
FJ6N-{3-[2,4-DIHYDROXY-5-(PROPAN-2-YL)PHENYL]-4-(4- METHOXYPHENYL)-1,2-OXAZOL-5-YL}CYCLOPROPANECARBOXAMIDE4lwiAK58 M98
A94N-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)METHYL]-3-{[(E)-(2-OXODIHYDROFURAN-3(2H)-YLIDENE)METHYL]AMINO}BENZENESULFONAMIDE2qg0AK58 M98 Y139
A94N-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)METHYL]-3-{[(E)-(2-OXODIHYDROFURAN-3(2H)-YLIDENE)METHYL]AMINO}BENZENESULFONAMIDE2qg0BK58 M98 Y139
SNX2-[(2-METHOXYETHYL)AMINO]-4-(4-OXO-1,2,3,4-TETRAHYDRO-9H-CARBAZOL-9-YL)BENZAMIDE3d0bAK58 M98 Y139
BD01-{4-[(2R)-1-(5-CHLORO-2,4-DIHYDROXYBENZOYL)PYRROLIDIN-2-YL]BENZYL}-3,3-DIFLUOROPYRROLIDINIUM3hekBK58 M98 Y139
JZB(5E,9E,11E)-13-CHLORO-14,16-DIHYDROXY-3,4,7,8-TETRAHYDRO-1H-2-BENZOXACYCLOTETRADECINE-1,11(12H)-DIONE 11-[O-(2-OXO-2-PIPERIDIN-1-YLETHYL)OXIME]3inwAK58 M98 Y139
JZC(5E,9E,11E)-14,16-DIHYDROXY-3,4,7,8-TETRAHYDRO-1H-2-BENZOXACYCLOTETRADECINE-1,11(12H)-DIONE 11-[O-(2-OXO-2-PIPERIDIN-1-YLETHYL)OXIME]3inxAK58 M98 Y139
SD12-[(3,4,5-TRIMETHOXYPHENYL)AMINO]-4-(2,6,6-TRIMETHYL-4-OXO-4,5,6,7-TETRAHYDRO-1H-INDOL-1-YL)BENZAMIDE3mnrPK58 M98 Y139
FU32-AMINO-N-CYCLOBUTYL-4-[2,4-DICHLORO-6-(4,4,4-TRIFLUOROBUTOXY)PHENYL]-5,7-DIHYDRO-6H-PYRROLO[3,4-D]PYRIMIDINE-6-CARBOXAMIDE3r4oBK58 M98 Y139
FU72-AMINO-4-{2,4-DICHLORO-6-[2-(1H-PYRAZOL-1-YL)ETHOXY]PHENYL}-N-(2,2-DIFLUOROPROPYL)-5,7-DIHYDRO-6H-PYRROLO[3,4-D]PYRIMIDINE-6-CARBOXAMIDE3r4pAK58 M98 Y139
FU72-AMINO-4-{2,4-DICHLORO-6-[2-(1H-PYRAZOL-1-YL)ETHOXY]PHENYL}-N-(2,2-DIFLUOROPROPYL)-5,7-DIHYDRO-6H-PYRROLO[3,4-D]PYRIMIDINE-6-CARBOXAMIDE3r4pBK58 M98 Y139
06H(6S)-4,6,15,15,18-PENTAMETHYL-5,17-DIOXO-2,3,4,5,6,7,14,15,16,17-DECAHYDRO-1H-12,8-(METHENO)[1,4,9]TRIAZACYCLOTETRADECINO[9,8-A]INDOLE-9-CARBOXAMIDE3r91AK58 M98 Y139
06T(5R,6S)-3-(L-ALANYL)-5,6,15,15,18-PENTAMETHYL-17-OXO-2,3,4,5,6,7,14,15,16,17-DECAHYDRO-1H-12,8-(METHENO)[1,5,9]TRIAZACYCLOTETRADECINO[1,2-A]INDOLE-9-CARBOXAMIDE3rkzAK58 M98 Y139
0TM2-{[4-(2-CHLORO-4,5-DIMETHOXYPHENYL)-5-CYANO-7H- PYRROLO[2,3-D]PYRIMIDIN-2-YL]SULFANYL}-N,N- DIMETHYLACETAMIDE4fcrAK58 M98 Y139
HIE4-[6,6-DIMETHYL-4-OXO-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL]-2-[(CIS-4-HYDROXYCYCLOHEXYL)AMINO]BENZAMIDE4nh7AK58 M98 Y139
HIE4-[6,6-DIMETHYL-4-OXO-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL]-2-[(CIS-4-HYDROXYCYCLOHEXYL)AMINO]BENZAMIDE4nh7BK58 M98 Y139
2LC2-FLUORO-6-[(3S)-TETRAHYDROFURAN-3-YLAMINO]-4-(3,6,6- TRIMETHYL-4-OXO-4,5,6,7-TETRAHYDRO-1H-INDOL-1-YL) BENZAMIDE4nh8AK58 M98 Y139
WHA4-{[4-AMINO-6-(5-CHLORO-1H,3H-BENZO[DE]ISOCHROMEN-6- YL)-1,3,5-TRIAZIN-2-YL]SULFANYL}BUTANAMIDE3whaAK58 M98 Y139
2Q92,7,7-TRIMETHYL-9-[1-OXO-8-(PROPAN-2-YLAMINO)-1,2,3,4- TETRAHYDROISOQUINOLIN-6-YL]-1,2,3,4,6,7,8,9-OCTAHYDRO- 5H-BETA-CARBOLIN-5-ONE4o05AK58 M98 Y139
IK9(2Z)-5-(1,3-BENZODIOXOL-5-YLMETHYL)-8-FLUORO- 10-[(2-HYDROXYETHYL)AMINO]-2-IMINO-2,3- DIHYDRO-1H-[1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-4- IUM4cwtAK58 M98 Y139
YUK2-[(TRANS-4-HYDROXYCYCLOHEXYL)AMINO]-4-[5-(4-PHENYL-1H- IMIDAZOL-1-YL)ISOQUINOLIN-1-YL]BENZAMIDE3wq9AK58 M98 Y139
40X(6S)-2-CHLORO-8,11,11-TRIMETHYL-9-OXO-6-PROPYL-6,7,9, 10,11,12-HEXAHYDROINDOLO[2,1-D][1,5]BENZOXAZEPINE-3- CARBOXAMIDE4xirAK58 M98 Y139
40Z2-CHLORO-5-(FURAN-2-YLMETHYL)-8,11,11-TRIMETHYL-9-OXO- 6,7,9,10,11,12-HEXAHYDRO-5H-INDOLO[1,2-A][1, 5]BENZODIAZEPINE-3-CARBOXAMIDE4xitAK58 M98 Y139
ADPADP1byqAM98
PU49-BUTYL-8-(4-METHOXYBENZYL)-9H-PURIN-6-AMINE1uy7AM98
PU59-BUTYL-8-(3-METHOXYBENZYL)-9H-PURIN-6-AMINE1uy8AM98
PU68-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H-1uy9AM98
PUZ8-(2,5-DIMETHOXY-BENZYL)-2-FLUORO-9-PENT-9H-PURIN-6-YLAMINE1uyiAM98
CT5CCT0181592bt0BM98
2D7N-(4-ACETYLPHENYL)-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE2byhAM98
4BH4-CHLORO-6-(4-PIPERAZIN-1-YL-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL2ccsAM98
2D94-CHLORO-6-(4-{4-[4-(METHYLSULFONYL)BENZYL]PIPERAZIN-1-YL}-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL2ccuAM98
H648-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE2fwyAM98
H718-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE2fwzAM98
LGAPYRIMIDIN-2-AMINE2jjcAM98
A134-METHYL-6-(TRIFLUOROMETHYL)PYRIMIDIN-2-AMINE2qfoAM98
2EQ5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-[4-(MORPHOLIN-4-YLMETHYL)PHENYL]ISOXAZOLE-3-CARBOXAMIDE2vcjAM98
ZZ24-(2-METHOXYETHOXY)-6-METHYLPYRIMIDIN-2-AMINE2wi1AM98
ZZ31,3,5-TRIAZIN-2-AMINE2wi2AM98
ZZ31,3,5-TRIAZIN-2-AMINE2wi2BM98
ZZ31,3,5-TRIAZIN-2-AMINE2wi3AM98
2KLS1498_SELLECK2wi7AM98
VHD4-(1,3-DIHYDRO-2H-ISOINDOL-2-YLCARBONYL)-6-(1-METHYLETHYL)BENZENE-1,3-DIOL2xabAM98
VHD4-(1,3-DIHYDRO-2H-ISOINDOL-2-YLCARBONYL)-6-(1-METHYLETHYL)BENZENE-1,3-DIOL2xabBM98
XDK2-AMINO-4-PYRIDYL-PYRIMIDINE2xdkAM98
2DL2-METHYL-4-DIETHYLAMIDE-PHENOL2xdlAM98
MT01-CHLORO-4-METHYLPHTHALAZINE2xdsAM98
LGAPYRIMIDIN-2-AMINE2xduAM98
WOE4-CHLORO-6-(2-METHOXYPHENYL)PYRIMIDIN-2-AMINE2xdxAM98
T5M2-TERT-BUTYL-4-(1,3-DIHYDRO-2H-ISOINDOL-2-YLCARBONYL)PHENOL2xhxAM98
XJX(2,4-DIHYDROXY-5-PROPAN-2-YL-PHENYL)-[5-[(4-METHYLPIPERAZIN-1-YL)METHYL]ISOINDOL-2-YL]METHANONE2xjxAM98
ADPADP2xk2AM98
XQIMETHYL 3,5-DIHYDROXYPHENYLACETATE2ye2AM98
2FY1-(2,4-DIHYDROXY-PHENYL)-PROPAN-1-ONE2ye4AM98
2A75-METHOXYRESORCINOL2ye5AM98
2AE2-AMINO-BENZAMIDE2ye6AM98
2GA2-[(3,5-DIMETHYL-1H-PYRAZOL-4-YL)SULFANYL]-5-METHYLSULFANYL-1,3,4-THIADIAZOLE2ye7AM98
2K41H-INDAZOL-6-OL2yebAM98
XQ03-METHYL-1H-INDAZOL-6-OL2yecAM98
ADEADENINE2yedAM98
2EC9-ETHYL-9H-PURIN-6-YLAMINE2yeeAM98
ANPAMP-PNP2yefAM98
XQG6-METHYLSULFANYL-9H-PURINE2yegBM98
2KUN-(3-METHOXYPROPYL)-9H-PURIN-6-AMINE2yehAM98
XQIMETHYL 3,5-DIHYDROXYPHENYLACETATE2yeiAM98
ZZ31,3,5-TRIAZIN-2-AMINE2yejAM98
YI54-CHLORO-6-[5-(3,4-DIMETHOXYPHENYL)-2,3-DIHYDRO-1,2,3-THIADIAZOL-4-YL]BENZENE-1,3-DIOL2yi5AM98
6QM4-[5-(4-ETHOXYPHENYL)-1,2,3-THIADIAZOL-4-YL]-6-ETHYLBENZENE-1,3-DIOL2yi6AM98
BZ84-CHLORO-6-[5-(4-ETHOXYPHENYL)-1,2,3-THIADIAZOL-4-YL BENZENE-1,3-DIOL2yi7AM98
YJW4-(5-METHYL-4-PHENYLISOXAZOL-3-YL)BENZENE-1,3-DIOL2yk2AM98
B2J4-(ETHYLTHIO)-6-METHYL-1,3,5-TRIAZIN-2-AMINE3b24BM98
B2K4-METHYL-6-(4-METHYLPHENYL)SULFONYL-PYRIMIDIN-2-AMINE3b25AM98
B2T4-(2-CHLOROPHENYL)-6-(METHYLSULFANYL)-1,3,5-TRIAZIN-2-AMINE3b27AM98
MO84-METHYL-7,8-DIHYDRO-5H-THIOPYRANO[4,3-D]PYRIMIDIN-2-AMINE3ft5AM98
42CN,N-DIMETHYL-7H-PURIN-6-AMINE3hyzAM98
42CN,N-DIMETHYL-7H-PURIN-6-AMINE3hyzBM98
42CN,N-DIMETHYL-7H-PURIN-6-AMINE3hz1AM98
PFT4-(1,3-DIHYDRO-2H-ISOINDOL-2-YLCARBONYL)BENZENE-1,3-DIOL3k99AM98
PFT4-(1,3-DIHYDRO-2H-ISOINDOL-2-YLCARBONYL)BENZENE-1,3-DIOL3k99DM98
P548-[(2,4-DIMETHYLPHENYL)SULFANYL]-3-PENT-4-YN-1-YL-3H-PURIN-6-AMINE3o0iAM98
MEX1-(2,4-DIHYDROXYPHENYL)-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE3ow6AM98
MEYN-{[1-(5-CHLORO-2,4-DIHYDROXYPHENYL)-2-OXO-2,3-DIHYDRO-1H-BENZIMIDAZOL-5-YL]METHYL}NAPHTHALENE-1-SULFONAMIDE3owdAM98
94M6-CHLORO-9-[(4-METHOXY-3,5-DIMETHYLPYRIDIN-2-YL)METHYL]-9H-PURIN-2-AMINE3qddAM98
WOE4-CHLORO-6-(2-METHOXYPHENYL)PYRIMIDIN-2-AMINE3r4mAM98
FU54-[2-CHLORO-6-(4,4,4-TRIFLUOROBUTOXY)PHENYL]-6-METHYLPYRIMIDIN-2-AMINE3r4nAM98
3RP4-(2,4-DICHLORO-5-METHOXYPHENYL)-6-METHYLPYRIMIDIN-2-AMINE3rlpBM98
3RQ4-(2,4-DICHLORO-5-METHOXYPHENYL)-2-METHYL-7H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE3rlqAM98
3RQ4-(2,4-DICHLORO-5-METHOXYPHENYL)-2-METHYL-7H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE3rlqBM98
3RR4-(2,4-DICHLORO-5-METHOXYPHENYL)-2,6-DIMETHYL-7H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE3rlrAM98
3RR4-(2,4-DICHLORO-5-METHOXYPHENYL)-2,6-DIMETHYL-7H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE3rlrBM98
ATPATP3t0zAM98
ACPADENOSINE 5'-[BETA,GAMMA-METHYLENE]TRIPHOSPHATE3t10AM98
ANPAMP-PNP3t1kAM98
ANPAMP-PNP3t1kBM98
AGSADENOSINE 5'-[GAMMA-THIO]TRIPHOSPHATE3t2sAM98
AGSADENOSINE 5'-[GAMMA-THIO]TRIPHOSPHATE3t2sBM98
VHA22-METHYL-13,18-DIOXA-7-THIA-3,5- DIAZATETRACYCLO[17.3.1.1~2,6~.1~8,12~]PENTACOSA-1(23), 2(25),3,5,8(24),9,11,19,21-NONAEN-4-AMINE3vhaAM98
EFUN-BENZYL-6-HYDROXY-N-METHYL-3-(3-METHYLBENZYL)-1H- INDAZOLE-5-CARBOXAMIDE4efuAM98
B2J4-(ETHYLTHIO)-6-METHYL-1,3,5-TRIAZIN-2-AMINE4egiAM98
42CN,N-DIMETHYL-7H-PURIN-6-AMINE4fcpAM98
42CN,N-DIMETHYL-7H-PURIN-6-AMINE4fcpBM98
2N64-(2,4-DIMETHYLPHENYL)-2-(METHYLSULFANYL)-7H-PYRROLO[2, 3-D]PYRIMIDINE-5-CARBONITRILE4fcqAM98
RL3[5-(6-BROMO[1,2,4]TRIAZOLO[4,3-A]PYRIDIN-3-YL)-2,4- DIHYDROXYPHENYL](4-METHYLPIPERAZIN-1-YL)METHANONE4l90AM98
X294-(6-BROMO[1,2,4]TRIAZOLO[4,3-A]PYRIDIN-3-YL)-6- CHLOROBENZENE-1,3-DIOL4l91AM98
S363,4-DIHYDROISOQUINOLIN-2(1H)-YL[2,4-DIHYDROXY-5- (PROPAN-2-YL)PHENYL]METHANONE4l93AM98
S363,4-DIHYDROISOQUINOLIN-2(1H)-YL[2,4-DIHYDROXY-5- (PROPAN-2-YL)PHENYL]METHANONE4l93BM98
TV25-(1,3-BENZODIOXOL-5-YLMETHYL)[1,2,4] TRIAZOLO[1,5-C]QUINAZOLIN-2-AMINE4cwpAM98
HAJ5-(1,3-BENZODIOXOL-5-YLMETHYL)-10-FLUORO[1,2, 4]TRIAZOLO[1,5-C]QUINAZOLIN-2-AMINE4cwrAM98
FJ34-(5-AMINO-1,2-OXAZOL-3-YL)-6-(PROPAN-2-YL)BENZENE-1,3- DIOL4lwfAM98
FJ41-(5-CHLORO-2,4-DIHYDROXYPHENYL)-2-(4-METHOXYPHENYL) ETHANONE4lwgAM98
3JC(7S)-2-AMINO-4-METHYL-7-PHENYL-7,8-DIHYDROQUINAZOLIN- 5(6H)-ONE4w7tAM98
PU39-BUTYL-8-(3,4,5-TRIMETHOXYBENZYL)-9H-PURIN-6-AMINE1uy6AM98 Y139
PU79-BUTYL-8-(2,5-DIMETHOXY-BENZYL)-9H-PURIN-6-YLAMINE1uycAM98 Y139
PU89-BUTYL-8-(2-CHLORO-3,4,5-TRIMETHOXY-BENZYL)-9H-PURIN-6-YLAMINE1uydAM98 Y139
PU98-(2-CHLORO-3,4,5-TRIMETHOXY-BENZYL)-9-PENT-4-YLNYL-9H-PURIN-6-YLAMINE1uyeAM98 Y139
PU18-(2-CHLORO-3,4,5-TRIMETHOXY-BENZYL)-2-FLUORO-9-PENT-4-YLNYL-9H-PURIN-6-YLAMINE1uyfAM98 Y139
PU28-(2,5-DIMETHOXY-BENZYL)-2-FLUORO-9H-PURIN-6-YLAMINE1uygAM98 Y139
PU09-BUTYL-8-(2,5-DIMETHOXY-BENZYL)-2-FLUORO-9H-PURIN-6-YLAMINE1uyhAM98 Y139
PUX8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-2-FLUORO-9H-PURIN-6-YLAMINE1uykAM98 Y139
A566-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE2qf6AM98 Y139
A566-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE2qf6CM98 Y139
A566-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE2qf6DM98 Y139
A913-({2-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)ETHYNYL]BENZYL}AMINO)-1,3-OXAZOL-2(3H)-ONE2qg2AM98 Y139
ZZ44-(2,4-DICHLOROPHENYL)-5-(2-PHENYLDIAZENYL)-2-PYRIMIDINAMINE2wi4AM98 Y139
ZZ53,6-DIAMINO-5-CYANO-4-(4-ETHOXYPHENYL)THIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE2wi5AM98 Y139
ZZ6THIENO[2,3-D]PYRIMIDINE2wi6AM98 Y139
MT01-CHLORO-4-METHYLPHTHALAZINE2xduAM98 Y139
C0P4-CHLORO-6-[2,4-DICHLORO-5-(2-MORPHOLIN-4-YLETHOXY)PHENYL]PYRIMIDIN-2-AMINE2xhrAM98 Y139
2D3METHYL 3-ISOXAZOL-5-YL-5-METHYL-1H-PYRAZOLE-4-CARBOXYLATE2ye8AM98 Y139
XQKMONOCARBOXYLIC ACID ANION2yeiAM98 Y139
XQKMONOCARBOXYLIC ACID ANION2yejAM98 Y139
YJX1-(3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-3,4-DIHYDROPYRIDO[2,1-A]ISOINDOL-6(2H)-ONE2yjxAM98 Y139
YJX1-(3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-3,4-DIHYDROPYRIDO[2,1-A]ISOINDOL-6(2H)-ONE2yk2AM98 Y139
YK94-(1H-IMIDAZO[4,5-C]PYRIDIN-2-YL)FLUOREN-9-ONE2yk9AM98 Y139
YKBN-[4-(3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-9H-FLUOREN-9-YL]-SUCCINAMIDE2ykbAM98 Y139
YKCN-[4-(3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-9H-FLUOREN-9-YL-ISONICOTINAMIDE2ykcAM98 Y139
YKEN-[(4R)-4-(3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-4H-FLUOREN-9-YL]QUINOLINE-5-CARBOXAMIDE2ykeAM98 Y139
YKI1-H-PYRROLO[2,3-B]PYRIDINE-4-CARBOXYLIC ACID[4-(3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-9H-FLUOREN-9-YL]-AMIDE2ykiAM98 Y139
YKJ2-AMINO-N-[4-(3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)--9H-FLUOREN-9-YL]-ISONICOTINAMIDE2ykjAM98 Y139
B2L4-(1H,3H-BENZO[DE]ISOCHROMEN-6-YL)-6-METHYLPYRIMIDIN-2-AMINE3b26AM98 Y139
B2X4-(5-CHLORO-1H,3H-BENZO[DE]ISOCHROMEN-6-YL)-6-(METHYLSULFANYL)-1,3,5-TRIAZIN-2-AMINE3b28AM98 Y139
B2X4-(5-CHLORO-1H,3H-BENZO[DE]ISOCHROMEN-6-YL)-6-(METHYLSULFANYL)-1,3,5-TRIAZIN-2-AMINE3b28BM98 Y139
MOJ(5E,7S)-2-AMINO-7-(4-FLUORO-2-PYRIDIN-3-YLPHENYL)-4-METHYL-7,8-DIHYDROQUINAZOLIN-5(6H)-ONE OXIME3ft8AM98 Y139
BD01-{4-[(2R)-1-(5-CHLORO-2,4-DIHYDROXYBENZOYL)PYRROLIDIN-2-YL]BENZYL}-3,3-DIFLUOROPYRROLIDINIUM3hekAM98 Y139
37DMETHYL 5-FURAN-2-YL-3-METHYL-1H-PYRAZOLE-4-CARBOXYLATE3hyyAM98 Y139
37DMETHYL 5-FURAN-2-YL-3-METHYL-1H-PYRAZOLE-4-CARBOXYLATE3hz1AM98 Y139
Z64N-[4-(5-FURAN-2-YL-3-METHYL-1H-PYRAZOL-4-YL)BUTYL]-N-METHYL-7H-PURIN-6-AMINE3hz5AM98 Y139
05S(6S)-6,15,15,18-TETRAMETHYL-17-OXO-2,3,4,5,6,7,14,15,16,17-DECAHYDRO-1H-8,12-(METHENO)[1,4,9]TRIAZACYCLOTETRADECINO[9,8-A]INDOLE-9-CARBOXAMIDE3qtfAM98 Y139
FU32-AMINO-N-CYCLOBUTYL-4-[2,4-DICHLORO-6-(4,4,4-TRIFLUOROBUTOXY)PHENYL]-5,7-DIHYDRO-6H-PYRROLO[3,4-D]PYRIMIDINE-6-CARBOXAMIDE3r4oAM98 Y139
06J(3AR)-13,13,16-TRIMETHYL-15-OXO-1,2,3,3A,4,5,12,14,15,17,18,19-DODECAHYDRO-13H-10,6-(METHENO)PYRROLO[2',1':3,4][1,4,9]TRIAZACYCLOTETRADECINO[9,8-A]INDOLE-7-CARBOXAMIDE3r92AM98 Y139
3RP4-(2,4-DICHLORO-5-METHOXYPHENYL)-6-METHYLPYRIMIDIN-2-AMINE3rlpAM98 Y139
EFT(2R)-3-CYCLOHEXYL-2-(6-HYDROXY-1H-INDAZOL-3-YL) PROPANENITRILE4eftAM98 Y139
FJ16,6-DIMETHYL-3-(TRIFLUOROMETHYL)-1,5,6,7-TETRAHYDRO-4H- INDAZOL-4-ONE4hy6AM98 Y139
WHA4-{[4-AMINO-6-(5-CHLORO-1H,3H-BENZO[DE]ISOCHROMEN-6- YL)-1,3,5-TRIAZIN-2-YL]SULFANYL}BUTANAMIDE3whaBM98 Y139
FGH2,7,7-TRIMETHYL-9-[8-(2-METHYLPROPYL)-1-OXO-1,2,3,4- TETRAHYDROISOQUINOLIN-6-YL]-1,2,3,4,6,7,8,9-OCTAHYDRO- 5H-BETA-CARBOLIN-5-ONE4o07AM98 Y139
2R68-(2-METHYLPROPYL)-6-(3,6,6-TRIMETHYL-4-OXO-4,5,6,7- TETRAHYDRO-1H-INDOL-1-YL)-3,4-DIHYDROISOQUINOLIN- 1(2H)-ONE4o09AM98 Y139
2QA8-CYCLOPENTYL-6-(3,6,6-TRIMETHYL-4-OXO-4,5,6,7- TETRAHYDRO-1H-INDOL-1-YL)-3,4-DIHYDROISOQUINOLIN- 1(2H)-ONE4o0bAM98 Y139
H055-PROPYL[1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-2- AMINE4cwfAM98 Y139
6LV5-(3,5-DIMETHOXYBENZYL)[1,2,4]TRIAZOLO[1,5-C] QUINAZOLIN-2-AMINE4cwnAM98 Y139
T625-(2-AMINO-[1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN- 5-YLMETHYL)-BENZENE-1,3-DIOL4cwoAM98 Y139
JR9N~3~-BENZYL-2-[(6-BROMO-1,3-BENZODIOXOL-5-YL) METHYL]IMIDAZO[1,2-A]PYRAZINE-3,8-DIAMINE4r3mAM98 Y139
990(7R)-2-AMINO-7-[4-FLUORO-2-(6-METHOXYPYRIDIN-2-YL) PHENYL]-4-METHYL-7,8-DIHYDROPYRIDO[4,3-D]PYRIMIDIN- 5(6H)-ONE4u93AM98 Y139
2Q84-(2,7,7-TRIMETHYL-5-OXO-1,2,3,4,5,6,7,8-OCTAHYDRO-9H- BETA-CARBOLIN-9-YL)BENZAMIDE4o04AM98 Y139
40W4-(3,6,6-TRIMETHYL-4-OXO-4,5,6,7-TETRAHYDRO-1H-INDOL-1- YL)BENZAMIDE4xipAM98 Y139
40Y8,11,11-TRIMETHYL-9-OXO-6,7,9,10,11,12- HEXAHYDROINDOLO[2,1-D][1,5]BENZOXAZEPINE-3-CARBOXAMIDE4xiqAM98 Y139
A566-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE2qf6BY139
A51(3E)-3-[(PHENYLAMINO)METHYLIDENE]DIHYDROFURAN-2(3H)-ONE2qfoAY139


Top
Conservation information for LBS of HSP90AA1
Multiple alignments for P07900 in multiple species
LBSAA sequence# speciesSpecies
A111NLGTIAKSGTK7Homo sapiens, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
A111NLGTIARSGTK6Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
A21EVETFAFQAEI7Homo sapiens, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
A21ETETFAFQAEI3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
A21DAETFAFQAEI3Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
A55SNSSDALDKIR13Homo sapiens, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglody
D102GMTKADLINNL6Homo sapiens, Danio rerio, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
D102GMTKADLVNNL4Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana, Gallus gallus
D102GMTKSDLVNNL3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
D54ISNSSDALDKI13Homo sapiens, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglody
D86IPNKQDRTLTI4Homo sapiens, Rattus norvegicus, Bos taurus, Pan troglodytes
D86VPDKASNTLSI3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
D86IPDKTNNTLTI3Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
D86IPDQKERTLTI1Danio rerio
D86IPNKHDRTLTI1Gallus gallus
D86IPSKQDRTLTI1Mus musculus
D93TLTIVDTGIGM6Homo sapiens, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
D93TLSIIDSGVGM3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
D93TLTIIDSGIGM3Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
D93TLTIIDTGIGM1Danio rerio
F138QFGVGFYSAYL12Homo sapiens, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana, Danio rerio, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
F138QFGVGSYSAYL1Gallus gallus
F170QAGGSFTVTRD6Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
F170SAGGSFTVRTD5Homo sapiens, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
F170AAGGSFTVKPD1Danio rerio
F170SAGGSFTVRLD1Gallus gallus
F22VETFAFQAEIA7Homo sapiens, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
F22TETFAFQAEIN3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
F22AETFAFQAEIN3Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
G108LINNLGTIAKS6Homo sapiens, Danio rerio, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
G108LVNNLGTIARS6Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
G108LVNNLGTIAKS1Gallus gallus
G132DISMIGQFGVG7Homo sapiens, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
G132DVSMIGQFGVG6Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
G135MIGQFGVGFYS12Homo sapiens, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana, Danio rerio, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
G135MIGQFGVGSYS1Gallus gallus
G137GQFGVGFYSAY12Homo sapiens, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana, Danio rerio, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
G137GQFGVGSYSAY1Gallus gallus
G97VDTGIGMTKAD6Homo sapiens, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
G97IDSGVGMTKSD3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
G97IDSGIGMTKAD3Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
G97IDTGIGMTKAD1Danio rerio
H154TVITKHNDDEQ7Homo sapiens, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
H154VVTTKHNDDEQ6Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
H189TKVILHLKEDQ6Homo sapiens, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus
H189TKITLYLKDDQ3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
H189TKMVLYLKEDQ2Arabidopsis thaliana, Arabidopsis thaliana
H189TKMILYLKEDQ1Arabidopsis thaliana
H189TKVIPHLKEDQ1Pan troglodytes
H77SGKELHINLIP5Homo sapiens, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
H77AQPELFIHIVP3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
H77GQPELFIHIIP3Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
H77SCKDLKIELIP1Danio rerio
H77SGKDLKINLIP1Gallus gallus
I104TKADLINNLGT6Homo sapiens, Danio rerio, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
I104TKADLVNNLGT4Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana, Gallus gallus
I104TKSDLVNNLGT3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
I110NNLGTIAKSGT7Homo sapiens, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
I110NNLGTIARSGT6Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
I26AFQAEIAQLMS7Homo sapiens, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
I26AFQAEINQLLS6Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
I91DRTLTIVDTGI6Homo sapiens, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
I91SNTLSIIDSGV3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
I91NNTLTIIDSGI3Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
I91ERTLTIIDTGI1Danio rerio
I96IVDTGIGMTKA6Homo sapiens, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
I96IIDSGVGMTKS3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
I96IIDSGIGMTKA3Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
I96IIDTGIGMTKA1Danio rerio
K112LGTIAKSGTKA7Homo sapiens, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
K112LGTIARSGTKE6Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
K58SDALDKIRYES7Homo sapiens, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
K58SDALDKIRFES6Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
L103MTKADLINNLG6Homo sapiens, Danio rerio, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
L103MTKADLVNNLG4Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana, Gallus gallus
L103MTKSDLVNNLG3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
L107DLINNLGTIAK6Homo sapiens, Danio rerio, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
L107DLVNNLGTIAR6Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
L107DLVNNLGTIAK1Gallus gallus
L48IFLRELISNSS13Homo sapiens, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglody
M98DTGIGMTKADL7Homo sapiens, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
M98DSGVGMTKSDL3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
M98DSGIGMTKADL3Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
N105KADLINNLGTI6Homo sapiens, Danio rerio, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
N105KADLVNNLGTI4Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana, Gallus gallus
N105KSDLVNNLGTI3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
N106ADLINNLGTIA6Homo sapiens, Danio rerio, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
N106ADLVNNLGTIA4Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana, Gallus gallus
N106SDLVNNLGTIA3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
N51RELISNSSDAL13Homo sapiens, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglody
N79KELHINLIPNK4Homo sapiens, Rattus norvegicus, Bos taurus, Pan troglodytes
N79PELFIHIVPDK3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
N79PELFIHIIPDK3Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
N79KDLKIELIPDQ1Danio rerio
N79KDLKINLIPNK1Gallus gallus
N79KELHINLIPSK1Mus musculus
Q23ETFAFQAEIAQ7Homo sapiens, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
Q23ETFAFQAEINQ6Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
R87PNKQDRTLTIV4Homo sapiens, Rattus norvegicus, Bos taurus, Pan troglodytes
R87PDKASNTLSII3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
R87PDKTNNTLTII3Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
R87PDQKERTLTII1Danio rerio
R87PNKHDRTLTIV1Gallus gallus
R87PSKQDRTLTIV1Mus musculus
S113GTIAKSGTKAF7Homo sapiens, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
S113GTIARSGTKEF6Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
S50LRELISNSSDA13Homo sapiens, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglody
S52ELISNSSDALD13Homo sapiens, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglody
T109INNLGTIAKSG6Homo sapiens, Danio rerio, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
T109VNNLGTIARSG6Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
T109VNNLGTIAKSG1Gallus gallus
T184PMGRGTKVILH4Homo sapiens, Mus musculus, Rattus norvegicus, Bos taurus
T184QLGRGTKITLY3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
T184ALGRGTKMILY1Arabidopsis thaliana
T184ALGRGTKMVLY1Arabidopsis thaliana
T184TLGRGTKMVLY1Arabidopsis thaliana
T184SIGRGTKVILH1Danio rerio
T184PLGRGTKVILH1Gallus gallus
T184PMGRGTKVIPH1Pan troglodytes
V136IGQFGVGFYSA12Homo sapiens, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana, Danio rerio, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
V136IGQFGVGSYSA1Gallus gallus
V150AEKVTVITKHN7Homo sapiens, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
V150AERVVVTTKHN3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
V150ADKVVVTTKHN3Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
V186GRGTKVILHLK6Homo sapiens, Danio rerio, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus
V186GRGTKITLYLK3Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica
V186GRGTKMVLYLK2Arabidopsis thaliana, Arabidopsis thaliana
V186GRGTKMILYLK1Arabidopsis thaliana
V186GRGTKVIPHLK1Pan troglodytes
W162DEQYAWESSAG6Homo sapiens, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
W162DEQYVWESQAG6Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana
W162DEQYIWESAAG1Danio rerio
Y139FGVGFYSAYLV12Homo sapiens, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Oryza sativa subsp. japonica, Arabidopsis thaliana, Arabidopsis thaliana, Arabidopsis thaliana, Danio rerio, Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
Y139FGVGSYSAYLV1Gallus gallus


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