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mutLBSgeneDB |
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| Gene summary for POLH |
 Gene summary |
| Basic gene Info. | Gene symbol | POLH |
| Gene name | polymerase (DNA directed), eta | |
| Synonyms | RAD30|RAD30A|XP-V|XPV | |
| Cytomap | UCSC genome browser: 6p21.1 | |
| Type of gene | protein-coding | |
| RefGenes | NM_001291969.1, NM_001291970.1,NM_006502.2, | |
| Description | DNA polymerase etaRAD30 homolog Axeroderma pigmentosum variant type protein | |
| Modification date | 20141219 | |
| dbXrefs | MIM : 603968 | |
| HGNC : HGNC | ||
| Ensembl : ENSG00000170734 | ||
| HPRD : 04913 | ||
| Vega : OTTHUMG00000014743 | ||
| Protein | UniProt: Q9Y253 go to UniProt's Cross Reference DB Table | |
| Expression | CleanEX: HS_POLH | |
| BioGPS: 5429 | ||
| Pathway | NCI Pathway Interaction Database: POLH | |
| KEGG: POLH | ||
| REACTOME: POLH | ||
| Pathway Commons: POLH | ||
| Context | iHOP: POLH | |
| ligand binding site mutation search in PubMed: POLH | ||
| UCL Cancer Institute: POLH | ||
| Assigned class in mutLBSgeneDB | C: This gene just belongs to mutLBSgenes. | |
| Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
| GO ID | GO Term | PubMed ID | GO:0000731 | DNA synthesis involved in DNA repair | 17563354 | GO:0010225 | response to UV-C | 17563354 |
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| Ligand binding site mutations for POLH |
| Lollipop-style diagram of mutations at LBS in amino-acid sequence. We represented ligand binding site mutations only. (You can see big image via clicking.)  : non-synonymous mutation on LBS, Circle size denotes number of samples. |
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| Cancer type specific mutLBS sorted by frequency |
| LBS | AAchange of nsSNV | Cancer type | # samples | H397 | D398Y | BLCA | 1 | D13 | D13G | COAD | 1 | R383 | R383C | COAD | 1 | Y52 | S51R | COAD | 1 | D15 | D15G | COAD | 1 | R377 | R377C | COAD | 1 | C635 | E636K | HNSC | 1 | R351 | T353A | STAD | 1 | I255 | R253C | STAD | 1 | H654 | H654N | UCEC | 1 | R93 | R93W | UCEC | 1 | R377 | K376E | UCEC | 1 | M14 | M14T | UCEC | 1 | H397 | S396I | UCEC | 1 |
| cf) Cancer type abbreviation. BLCA: Bladder urothelial carcinoma, BRCA: Breast invasive carcinoma, CESC: Cervical squamous cell carcinoma and endocervical adenocarcinoma, COAD: Colon adenocarcinoma, GBM: Glioblastoma multiforme, LGG: Brain lower grade glioma, HNSC: Head and neck squamous cell carcinoma, KICH: Kidney chromophobe, KIRC: Kidney renal clear cell carcinoma, KIRP: Kidney renal papillary cell carcinoma, LAML: Acute myeloid leukemia, LUAD: Lung adenocarcinoma, LUSC: Lung squamous cell carcinoma, OV: Ovarian serous cystadenocarcinoma, PAAD: Pancreatic adenocarcinoma, PRAD: Prostate adenocarcinoma, SKCM: Skin cutaneous melanoma, STAD: Stomach adenocarcinoma, THCA: Thyroid carcinoma, UCEC: Uterine corpus endometrial carcinoma. |
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| Protein structure related information for POLH |
| Relative protein structure stability change (ΔΔE) using Mupro 1.1 Mupro score denotes assessment of the effect of mutations on thermodynamic stability. (ΔΔE<0: mutation decreases stability, ΔΔE>0: mutation increases stability) |
 : nsSNV at non-LBS : nsSNV at LBS |
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| nsSNVs sorted by the relative stability change of protein structure by each mutation Blue: mutations of positive stability change. and red : the most recurrent mutation for this gene. |
| LBS | AAchange of nsSNV | Relative stability change | Y52 | S51R | 0.11014431 | M14 | M14T | -1.7260639 | C635 | E636K | -1.5106602 | D15 | D15G | -1.4217502 | R351 | T353A | -1.2106901 | I255 | R253C | -1.1635243 | R377 | R377C | -0.98995087 | R383 | R383C | -0.97252658 | H654 | H654N | -0.86470044 | R93 | R93W | -0.81669497 | D13 | D13G | -0.81177015 | H397 | D398Y | -0.35245438 | H397 | S396I | -0.35093044 | R377 | K376E | -0.050288272 |
| (MuPro1.1: Jianlin Cheng et al., Prediction of Protein Stability Changes for Single-Site Mutations Using Support Vector Machines, PROTEINS: Structure, Function, and Bioinformatics. 2006, 62:1125-1132) |
| Structure image for POLH from PDB |
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| Differential gene expression and gene-gene network for POLH |
| Differential gene expression between mutated and non-mutated LBS samples in all 16 major cancer types |
| Differential co-expressed gene network based on protein-protein interaction data (CePIN) |
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| Phenotype information for POLH |
| Gene level disease information (DisGeNet) |
| Disease ID | Disease name | # PubMed | Association type |
| umls:C0043346 | Xeroderma Pigmentosum | 26 | Biomarker, GeneticVariation |
| umls:C1848410 | Xeroderma pigmentosum, variant type | 5 | Biomarker, GeneticVariation |
| Mutation level pathogenic information (ClinVar annotation) |
| Allele ID | AA change | Clinical significance | Origin | Phenotype IDs |
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| Pharmacological information for POLH |
| Gene expression profile of anticancer drug treated cell-lines (CCLE) Heatmap showing the correlation between gene expression and drug response across all the cell-lines. We chose the top 20 among 138 drugs.We used Pearson's correlation coefficient. |
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| Drug information targeting mutLBSgene (Approved drugs only) |
| Drug status | DrugBank ID | Name | Type | Drug structure |
| Gene-centered ligand-gene interaction network |
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| Ligands binding to mutated ligand binding site of POLH go to BioLip |
| Ligand ID | Ligand short name | Ligand long name | PDB ID | PDB name | mutLBS | ZN | ZINC(2+) | 3wup | A | C635 H654 | MG | MAGNESIUM(2+) | 3mr2 | A | D13 | MG | MAGNESIUM(2+) | 3mr3 | A | D13 | MG | MAGNESIUM(2+) | 3mr5 | A | D13 | MG | MAGNESIUM(2+) | 3mr6 | A | D13 | MG | MAGNESIUM(2+) | 3si8 | A | D13 | MG | MAGNESIUM(2+) | 4dl2 | A | D13 | MG | MAGNESIUM(2+) | 4dl3 | A | D13 | MG | MAGNESIUM(2+) | 4dl4 | A | D13 | MG | MAGNESIUM(2+) | 4dl5 | A | D13 | MG | MAGNESIUM(2+) | 4dl6 | A | D13 | MG | MAGNESIUM(2+) | 4ecr | A | D13 | MG | MAGNESIUM(2+) | 4ecs | A | D13 | MG | MAGNESIUM(2+) | 4ect | A | D13 | MG | MAGNESIUM(2+) | 4ecu | A | D13 | MG | MAGNESIUM(2+) | 4ecv | A | D13 | MG | MAGNESIUM(2+) | 4ecw | A | D13 | MG | MAGNESIUM(2+) | 4ecx | A | D13 | MG | MAGNESIUM(2+) | 4ed8 | A | D13 | MG | MAGNESIUM(2+) | 4j9k | A | D13 | MG | MAGNESIUM(2+) | 4j9l | A | D13 | MG | MAGNESIUM(2+) | 4j9m | A | D13 | MG | MAGNESIUM(2+) | 4j9n | A | D13 | MG | MAGNESIUM(2+) | 4j9o | A | D13 | MG | MAGNESIUM(2+) | 4j9q | A | D13 | MG | MAGNESIUM(2+) | 4o3n | A | D13 | MG | MAGNESIUM(2+) | 4o3o | A | D13 | MG | MAGNESIUM(2+) | 4o3p | A | D13 | MG | MAGNESIUM(2+) | 4o3q | A | D13 | MG | MAGNESIUM(2+) | 4o3r | A | D13 | MG | MAGNESIUM(2+) | 4o3s | A | D13 | MG | MAGNESIUM(2+) | 4q8e | A | D13 | MG | MAGNESIUM(2+) | 4q8f | A | D13 | MG | MAGNESIUM(2+) | 4rnm | A | D13 | MG | MAGNESIUM(2+) | 4rnn | A | D13 | CA | CALCIUM(2+) | 4yp3 | A | D13 | CA | CALCIUM(2+) | 4yqw | A | D13 | CA | CALCIUM(2+) | 4yr0 | A | D13 | CA | CALCIUM(2+) | 4yr2 | A | D13 | CA | CALCIUM(2+) | 4yr3 | A | D13 | MG | MAGNESIUM(2+) | 4ru9 | A | D13 | MG | MAGNESIUM(2+) | 3jaa | A | D13 | CA | CALCIUM(2+) | 5ewe | A | D13 | MG | MAGNESIUM(2+) | 3mr2 | A | D13 M14 | MG | MAGNESIUM(2+) | 3mr3 | A | D13 M14 | MG | MAGNESIUM(2+) | 3mr5 | A | D13 M14 | MG | MAGNESIUM(2+) | 3mr6 | A | D13 M14 | MG | MAGNESIUM(2+) | 3si8 | A | D13 M14 | MG | MAGNESIUM(2+) | 4dl2 | A | D13 M14 | MG | MAGNESIUM(2+) | 4dl3 | A | D13 M14 | MG | MAGNESIUM(2+) | 4dl4 | A | D13 M14 | MG | MAGNESIUM(2+) | 4dl5 | A | D13 M14 | MG | MAGNESIUM(2+) | 4dl6 | A | D13 M14 | CA | CALCIUM(2+) | 4ecq | A | D13 M14 | CA | CALCIUM(2+) | 4ecr | A | D13 M14 | MG | MAGNESIUM(2+) | 4ecr | A | D13 M14 | CA | CALCIUM(2+) | 4ecs | A | D13 M14 | MG | MAGNESIUM(2+) | 4ecs | A | D13 M14 | CA | CALCIUM(2+) | 4ect | A | D13 M14 | MG | MAGNESIUM(2+) | 4ect | A | D13 M14 | CA | CALCIUM(2+) | 4ecu | A | D13 M14 | MG | MAGNESIUM(2+) | 4ecu | A | D13 M14 | CA | CALCIUM(2+) | 4ecv | A | D13 M14 | MG | MAGNESIUM(2+) | 4ecv | A | D13 M14 | CA | CALCIUM(2+) | 4ecw | A | D13 M14 | MG | MAGNESIUM(2+) | 4ecw | A | D13 M14 | CA | CALCIUM(2+) | 4ecx | A | D13 M14 | MG | MAGNESIUM(2+) | 4ecx | A | D13 M14 | CA | CALCIUM(2+) | 4ecy | A | D13 M14 | CA | CALCIUM(2+) | 4ecz | A | D13 M14 | CA | CALCIUM(2+) | 4ed0 | A | D13 M14 | CA | CALCIUM(2+) | 4ed1 | A | D13 M14 | CA | CALCIUM(2+) | 4ed2 | A | D13 M14 | CA | CALCIUM(2+) | 4ed3 | A | D13 M14 | CA | CALCIUM(2+) | 4ed7 | A | D13 M14 | CA | CALCIUM(2+) | 4ed8 | A | D13 M14 | MG | MAGNESIUM(2+) | 4ed8 | A | D13 M14 | MG | MAGNESIUM(2+) | 4eey | A | D13 M14 | MG | MAGNESIUM(2+) | 4j9k | A | D13 M14 | MG | MAGNESIUM(2+) | 4j9l | A | D13 M14 | MG | MAGNESIUM(2+) | 4j9m | A | D13 M14 | MG | MAGNESIUM(2+) | 4j9n | A | D13 M14 | MG | MAGNESIUM(2+) | 4j9o | A | D13 M14 | MG | MAGNESIUM(2+) | 4o3n | A | D13 M14 | MG | MAGNESIUM(2+) | 4o3o | A | D13 M14 | MG | MAGNESIUM(2+) | 4o3p | A | D13 M14 | MG | MAGNESIUM(2+) | 4o3q | A | D13 M14 | MG | MAGNESIUM(2+) | 4o3r | A | D13 M14 | MG | MAGNESIUM(2+) | 4o3s | A | D13 M14 | MG | MAGNESIUM(2+) | 4q8e | A | D13 M14 | MG | MAGNESIUM(2+) | 4q8f | A | D13 M14 | MG | MAGNESIUM(2+) | 4rnm | A | D13 M14 | MG | MAGNESIUM(2+) | 4rnn | A | D13 M14 | CA | CALCIUM(2+) | 4rno | A | D13 M14 | CA | CALCIUM(2+) | 4yp3 | A | D13 M14 | CA | CALCIUM(2+) | 4yqw | A | D13 M14 | CA | CALCIUM(2+) | 4yr0 | A | D13 M14 | CA | CALCIUM(2+) | 4yr2 | A | D13 M14 | CA | CALCIUM(2+) | 4yr3 | A | D13 M14 | MG | MAGNESIUM(2+) | 4ru9 | A | D13 M14 | MG | MAGNESIUM(2+) | 3jaa | A | D13 M14 | CA | CALCIUM(2+) | 5ewe | A | D13 M14 | CA | CALCIUM(2+) | 5ewf | A | D13 M14 | CA | CALCIUM(2+) | 5ewg | A | D13 M14 | DZ4 | 2'-DEOXY-5'-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]AMINO}PHOSPHORYL]ADENOSINE | 3mr2 | A | D13 M14 D15 Y52 | DZ4 | 2'-DEOXY-5'-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]AMINO}PHOSPHORYL]ADENOSINE | 3mr3 | A | D13 M14 D15 Y52 | XG4 | DGMPNPP | 3mr5 | A | D13 M14 D15 Y52 | XG4 | DGMPNPP | 3mr6 | A | D13 M14 D15 Y52 | DZ4 | 2'-DEOXY-5'-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]AMINO}PHOSPHORYL]ADENOSINE | 3si8 | A | D13 M14 D15 Y52 | 0KX | DCMPNPP | 4dl2 | A | D13 M14 D15 Y52 | 0KX | DCMPNPP | 4dl3 | A | D13 M14 D15 Y52 | 0KX | DCMPNPP | 4dl4 | A | D13 M14 D15 Y52 | 0KX | DCMPNPP | 4dl5 | A | D13 M14 D15 Y52 | XG4 | DGMPNPP | 4dl6 | A | D13 M14 D15 Y52 | DTP | DATP(4-) | 4ecq | A | D13 M14 D15 Y52 | DTP | DATP(4-) | 4ecr | A | D13 M14 D15 Y52 | DTP | DATP(4-) | 4ecs | A | D13 M14 D15 Y52 | DTP | DATP(4-) | 4ect | A | D13 M14 D15 Y52 | DTP | DATP(4-) | 4ecu | A | D13 M14 D15 Y52 | DTP | DATP(4-) | 4ecv | A | D13 M14 D15 Y52 | DTP | DATP(4-) | 4ecw | A | D13 M14 D15 Y52 | DTP | DATP(4-) | 4ecx | A | D13 M14 D15 Y52 | DTP | DATP(4-) | 4ecz | A | D13 M14 D15 Y52 | DTP | DATP(4-) | 4ed0 | A | D13 M14 D15 Y52 | DTP | DATP(4-) | 4ed1 | A | D13 M14 D15 Y52 | DTP | DATP(4-) | 4ed2 | A | D13 M14 D15 Y52 | DTP | DATP(4-) | 4ed3 | A | D13 M14 D15 Y52 | DTP | DATP(4-) | 4ed8 | A | D13 M14 D15 Y52 | DCP | DCTP | 4eey | A | D13 M14 D15 Y52 | XG4 | DGMPNPP | 4j9k | A | D13 M14 D15 Y52 | XG4 | DGMPNPP | 4j9l | A | D13 M14 D15 Y52 | XG4 | DGMPNPP | 4j9m | A | D13 M14 D15 Y52 | XG4 | DGMPNPP | 4j9n | A | D13 M14 D15 Y52 | DZ4 | 2'-DEOXY-5'-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]AMINO}PHOSPHORYL]ADENOSINE | 4j9o | A | D13 M14 D15 Y52 | 0KX | DCMPNPP | 4o3n | A | D13 M14 D15 Y52 | DZ4 | 2'-DEOXY-5'-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]AMINO}PHOSPHORYL]ADENOSINE | 4o3o | A | D13 M14 D15 Y52 | 0KX | DCMPNPP | 4o3p | A | D13 M14 D15 Y52 | XG4 | DGMPNPP | 4o3q | A | D13 M14 D15 Y52 | 0KX | DCMPNPP | 4o3r | A | D13 M14 D15 Y52 | 0KX | DCMPNPP | 4o3s | A | D13 M14 D15 Y52 | 0KX | DCMPNPP | 4q8e | A | D13 M14 D15 Y52 | XG4 | DGMPNPP | 4q8f | A | D13 M14 D15 Y52 | DZ4 | 2'-DEOXY-5'-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]AMINO}PHOSPHORYL]ADENOSINE | 4rnm | A | D13 M14 D15 Y52 | XG4 | DGMPNPP | 4rnn | A | D13 M14 D15 Y52 | DCP | DCTP | 4yp3 | A | D13 M14 D15 Y52 | DCP | DCTP | 4yqw | A | D13 M14 D15 Y52 | DCP | DCTP | 4yr0 | A | D13 M14 D15 Y52 | DTP | DATP(4-) | 4yr2 | A | D13 M14 D15 Y52 | DCP | DCTP | 4yr3 | A | D13 M14 D15 Y52 | 0KX | DCMPNPP | 4ru9 | A | D13 M14 D15 Y52 | DZ4 | 2'-DEOXY-5'-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]AMINO}PHOSPHORYL]ADENOSINE | 3jaa | A | D13 M14 D15 Y52 | CTP | CTP | 5ewe | A | D13 M14 D15 Y52 | CTP | CTP | 5ewf | A | D13 M14 D15 Y52 | ATP | ATP | 5ewg | A | D13 M14 D15 Y52 | DCP | DCTP | 4rno | A | D13 M14 Y52 | NUC | Nucleic Acids | 4ecs | A | D13 R377 | NUC | Nucleic Acids | 4ecv | A | D13 R377 | NUC | Nucleic Acids | 4ect | A | D13 R377 R383 | NUC | Nucleic Acids | 4ecu | A | D13 R377 R383 | NUC | Nucleic Acids | 4ecw | A | D13 R377 R383 | NUC | Nucleic Acids | 4ecx | A | D13 R377 R383 | NUC | Nucleic Acids | 4j9p | A | D13 R377 R383 | CO | COBALT(2+) | 3si8 | A | H397 | NUC | Nucleic Acids | 4rno | A | I255 R377 R383 | DTP | DATP(4-) | 4ecy | A | M14 D15 Y52 | DTP | DATP(4-) | 4ed7 | A | M14 D15 Y52 | NUC | Nucleic Acids | 3si8 | A | R351 | NUC | Nucleic Acids | 4q8f | A | R351 | NUC | Nucleic Acids | 5ewf | A | R351 | NUC | Nucleic Acids | 4dl4 | A | R377 | NUC | Nucleic Acids | 4dl6 | A | R377 | NUC | Nucleic Acids | 4ecq | A | R377 | NUC | Nucleic Acids | 4ecy | A | R377 | NUC | Nucleic Acids | 4ecz | A | R377 | NUC | Nucleic Acids | 4ed0 | A | R377 | NUC | Nucleic Acids | 4ed3 | A | R377 | NUC | Nucleic Acids | 4ed7 | A | R377 | NUC | Nucleic Acids | 4j9o | A | R377 | NUC | Nucleic Acids | 4j9r | A | R377 | NUC | Nucleic Acids | 4j9s | A | R377 | NUC | Nucleic Acids | 4q8e | A | R377 | NUC | Nucleic Acids | 3mr2 | A | R377 R383 | NUC | Nucleic Acids | 3mr3 | A | R377 R383 | NUC | Nucleic Acids | 3mr6 | A | R377 R383 | NUC | Nucleic Acids | 3si8 | A | R377 R383 | NUC | Nucleic Acids | 3tq1 | A | R377 R383 | NUC | Nucleic Acids | 4dl2 | A | R377 R383 | NUC | Nucleic Acids | 4dl3 | A | R377 R383 | NUC | Nucleic Acids | 4ecr | A | R377 R383 | NUC | Nucleic Acids | 4ed1 | A | R377 R383 | NUC | Nucleic Acids | 4ed2 | A | R377 R383 | NUC | Nucleic Acids | 4ed6 | A | R377 R383 | NUC | Nucleic Acids | 4ed8 | A | R377 R383 | NUC | Nucleic Acids | 4eey | A | R377 R383 | NUC | Nucleic Acids | 4j9k | A | R377 R383 | NUC | Nucleic Acids | 4j9l | A | R377 R383 | NUC | Nucleic Acids | 4j9m | A | R377 R383 | NUC | Nucleic Acids | 4j9n | A | R377 R383 | NUC | Nucleic Acids | 4j9q | A | R377 R383 | NUC | Nucleic Acids | 4o3n | A | R377 R383 | NUC | Nucleic Acids | 4o3p | A | R377 R383 | NUC | Nucleic Acids | 4o3q | A | R377 R383 | NUC | Nucleic Acids | 4o3r | A | R377 R383 | NUC | Nucleic Acids | 4rnm | A | R377 R383 | NUC | Nucleic Acids | 4rnn | A | R377 R383 | NUC | Nucleic Acids | 4yqw | A | R377 R383 | NUC | Nucleic Acids | 4yr0 | A | R377 R383 | NUC | Nucleic Acids | 3jaa | A | R377 R383 | NUC | Nucleic Acids | 5ewe | A | R377 R383 | NUC | Nucleic Acids | 5ewf | A | R377 R383 | NUC | Nucleic Acids | 5ewg | A | R377 R383 | NUC | Nucleic Acids | 4o3o | A | R383 | NUC | Nucleic Acids | 4o3s | A | R383 | NUC | Nucleic Acids | 4q8f | A | R383 | NUC | Nucleic Acids | 4yp3 | A | R383 | NUC | Nucleic Acids | 4yr3 | A | R383 | NUC | Nucleic Acids | 4ru9 | A | R383 | NUC | Nucleic Acids | 3mr2 | A | R93 R351 | NUC | Nucleic Acids | 3mr3 | A | R93 R351 | NUC | Nucleic Acids | 3mr5 | A | R93 R351 | NUC | Nucleic Acids | 3mr6 | A | R93 R351 | NUC | Nucleic Acids | 3tq1 | A | R93 R351 | NUC | Nucleic Acids | 4dl2 | A | R93 R351 | NUC | Nucleic Acids | 4dl3 | A | R93 R351 | NUC | Nucleic Acids | 4dl4 | A | R93 R351 | NUC | Nucleic Acids | 4dl5 | A | R93 R351 | NUC | Nucleic Acids | 4dl6 | A | R93 R351 | NUC | Nucleic Acids | 4dl7 | A | R93 R351 | NUC | Nucleic Acids | 4ecq | A | R93 R351 | NUC | Nucleic Acids | 4ecr | A | R93 R351 | NUC | Nucleic Acids | 4ecs | A | R93 R351 | NUC | Nucleic Acids | 4ect | A | R93 R351 | NUC | Nucleic Acids | 4ecu | A | R93 R351 | NUC | Nucleic Acids | 4ecv | A | R93 R351 | NUC | Nucleic Acids | 4ecw | A | R93 R351 | NUC | Nucleic Acids | 4ecx | A | R93 R351 | NUC | Nucleic Acids | 4ecy | A | R93 R351 | NUC | Nucleic Acids | 4ecz | A | R93 R351 | NUC | Nucleic Acids | 4ed0 | A | R93 R351 | NUC | Nucleic Acids | 4ed1 | A | R93 R351 | NUC | Nucleic Acids | 4ed2 | A | R93 R351 | NUC | Nucleic Acids | 4ed3 | A | R93 R351 | NUC | Nucleic Acids | 4ed6 | A | R93 R351 | NUC | Nucleic Acids | 4ed7 | A | R93 R351 | NUC | Nucleic Acids | 4ed8 | A | R93 R351 | NUC | Nucleic Acids | 4eey | A | R93 R351 | NUC | Nucleic Acids | 4j9k | A | R93 R351 | NUC | Nucleic Acids | 4j9l | A | R93 R351 | NUC | Nucleic Acids | 4j9m | A | R93 R351 | NUC | Nucleic Acids | 4j9n | A | R93 R351 | NUC | Nucleic Acids | 4j9o | A | R93 R351 | NUC | Nucleic Acids | 4j9p | A | R93 R351 | NUC | Nucleic Acids | 4j9q | A | R93 R351 | NUC | Nucleic Acids | 4j9r | A | R93 R351 | NUC | Nucleic Acids | 4j9s | A | R93 R351 | NUC | Nucleic Acids | 4o3n | A | R93 R351 | NUC | Nucleic Acids | 4o3o | A | R93 R351 | NUC | Nucleic Acids | 4o3p | A | R93 R351 | NUC | Nucleic Acids | 4o3q | A | R93 R351 | NUC | Nucleic Acids | 4o3r | A | R93 R351 | NUC | Nucleic Acids | 4o3s | A | R93 R351 | NUC | Nucleic Acids | 4q8e | A | R93 R351 | NUC | Nucleic Acids | 4rnm | A | R93 R351 | NUC | Nucleic Acids | 4rnn | A | R93 R351 | NUC | Nucleic Acids | 4rno | A | R93 R351 | NUC | Nucleic Acids | 4yp3 | A | R93 R351 | NUC | Nucleic Acids | 4yqw | A | R93 R351 | NUC | Nucleic Acids | 4yr0 | A | R93 R351 | NUC | Nucleic Acids | 4yr2 | A | R93 R351 | NUC | Nucleic Acids | 4yr3 | A | R93 R351 | NUC | Nucleic Acids | 4ru9 | A | R93 R351 | NUC | Nucleic Acids | 3jaa | A | R93 R351 | NUC | Nucleic Acids | 5ewe | A | R93 R351 | NUC | Nucleic Acids | 5ewg | A | R93 R351 |
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| Conservation information for LBS of POLH |
| Multiple alignments for Q9Y253 in multiple species |
| LBS | AA sequence | # species | Species |
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