mutLBSgeneDB

mutLBSgeneDB
mutated Ligand Binding Site gene DataBase

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	Gene Summary
	Ligand Binding Site Mutation Information
	Protein Structure Related Information
	Gene Expression and Gene-Gene Network
	Phenotype Information
	Pharmacological Information
	Conservation Information for LBS

Gene summary for MOB1A

Gene summary

Basic gene Info.	Gene symbol	MOB1A
	Gene name	MOB kinase activator 1A
	Synonyms	C2orf6\|MATS1\|MOB1\|MOBK1B\|MOBKL1B\|Mob4B
	Cytomap	UCSC genome browser: 2p13.1
	Type of gene	protein-coding
	RefGenes	NM_018221.3,
	Description	MOB1 Mps One Binder homolog AMOB1, Mps One Binder kinase activator-like 1Bmob1 alphamob1 homolog 1Bmps one binder kinase activator-like 1B
	Modification date	20141207
dbXrefs	MIM : 609281
	HGNC : HGNC
	HPRD : 14727
Protein	UniProt: Q9H8S9 go to UniProt's Cross Reference DB Table
Expression	CleanEX: HS_MOB1A
	BioGPS: 55233
Pathway	NCI Pathway Interaction Database: MOB1A
	KEGG: MOB1A
	REACTOME: MOB1A
	Pathway Commons: MOB1A
Context	iHOP: MOB1A
	ligand binding site mutation search in PubMed: MOB1A
	UCL Cancer Institute: MOB1A
Assigned class in mutLBSgeneDB	C: This gene just belongs to mutLBSgenes.

Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez

GO ID	GO Term	PubMed ID
GO:0035329	hippo signaling	19739119

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Ligand binding site mutations for MOB1A

Lollipop-style diagram of mutations at LBS in amino-acid sequence.
We represented ligand binding site mutations only. (You can see big image via clicking.)

: non-synonymous mutation on LBS, Circle size denotes number of samples.

Cancer type specific mutLBS sorted by frequency

LBS	AAchange of nsSNV	Cancer type	# samples
F65	F64L	COAD	1
R154	R154H	STAD	1
P106	P106L	THCA	1

cf) Cancer type abbreviation. BLCA: Bladder urothelial carcinoma, BRCA: Breast invasive carcinoma, CESC: Cervical squamous cell carcinoma and endocervical adenocarcinoma, COAD: Colon adenocarcinoma, GBM: Glioblastoma multiforme, LGG: Brain lower grade glioma, HNSC: Head and neck squamous cell carcinoma, KICH: Kidney chromophobe, KIRC: Kidney renal clear cell carcinoma, KIRP: Kidney renal papillary cell carcinoma, LAML: Acute myeloid leukemia, LUAD: Lung adenocarcinoma, LUSC: Lung squamous cell carcinoma, OV: Ovarian serous cystadenocarcinoma, PAAD: Pancreatic adenocarcinoma, PRAD: Prostate adenocarcinoma, SKCM: Skin cutaneous melanoma, STAD: Stomach adenocarcinoma, THCA: Thyroid carcinoma, UCEC: Uterine corpus endometrial carcinoma.

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Protein structure related information for MOB1A

Relative protein structure stability change (ΔΔE) using Mupro 1.1
Mupro score denotes assessment of the effect of mutations on thermodynamic stability.
(ΔΔE<0: mutation decreases stability, ΔΔE>0: mutation increases stability)

: nsSNV at non-LBS

: nsSNV at LBS

nsSNVs sorted by the relative stability change of protein structure by each mutation
Blue: mutations of positive stability change. and red : the most recurrent mutation for this gene.

LBS	AAchange of nsSNV	Relative stability change
R154	R154H	-1.3578534
F65	F64L	-0.63852692
P106	P106L	-0.50237453

(MuPro1.1: Jianlin Cheng et al., Prediction of Protein Stability Changes for Single-Site Mutations Using Support Vector Machines, PROTEINS: Structure, Function, and Bioinformatics. 2006, 62:1125-1132)

Structure image for MOB1A from PDB

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Differential gene expression and gene-gene network for MOB1A

Differential gene expression between mutated and non-mutated LBS samples in all 16 major cancer types

Differential co-expressed gene network based on protein-protein interaction data (CePIN)

* Left PPI network was created from samples with mutations in the LBS of MOB1A and the right PPI network was created from samples without mutations in the LBS of MOB1A. Only genes with p-value < 0.05 are shown.
Red circle: input gene. Orange circle: LBSgene. Blue circle: other gene.

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Phenotype information for MOB1A

Gene level disease information (DisGeNet)

Disease ID

Disease name

# PubMed

Association type

Mutation level pathogenic information (ClinVar annotation)

Allele ID

AA change

Clinical significance

Origin

Phenotype IDs

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Pharmacological information for MOB1A

Gene expression profile of anticancer drug treated cell-lines (CCLE)
Heatmap showing the correlation between gene expression and drug response across all the cell-lines. We chose the top 20 among 138 drugs.We used Pearson's correlation coefficient.

Drug information targeting mutLBSgene (Approved drugs only)

Drug status

DrugBank ID

Name

Type

Drug structure

Gene-centered ligand-gene interaction network

Ligands binding to mutated ligand binding site of MOB1A go to BioLip

Ligand ID	Ligand short name	Ligand long name	PDB ID	PDB name	mutLBS
III		Peptide ligand (LYS,ARG,ASN,ALA,THR,SER,PRO,GLN,VAL,GLN,ARG,PRO,SER,PHE,MET,ASP,TYR)	5brm	A	F65
III		Peptide ligand (SER,PRO,GLN,VAL,GLN,ARG,PRO,SER,PHE,MET,ASP,TYR)	5brm	C	F65
III		Peptide ligand (PRO,GLN,VAL,GLN,ARG,PRO,SER,PHE)	5brm	D	F65
III		Peptide ligand (PRO,GLN,VAL,GLN,ARG,PRO,SER,PHE)	5brm	E	F65
III		Peptide ligand (LYS,ARG,ASN,ALA,THR,SER,PRO,GLN,VAL,GLN,ARG,PRO,SER,PHE,MET,ASP,TYR)	5brm	F	F65
III		Peptide ligand (GLY,THR,MET,LYS,ARG,ASN,ALA,THR,SER,PRO,GLN,VAL,GLN,ARG,PRO,SER,PHE,MET,ASP,TYR,PHE,ASP)	5brm	A	P106 R154
III		Peptide ligand (THR,MET,LYS)	5brm	E	P106 R154
III		Peptide ligand (THR,MET,LYS,ARG,ASN)	5brm	F	P106 R154
III		Peptide ligand (ALA,LEU,PRO,ALA,TRP,ALA,ARG,PRO,ASP)	4j1v	A	R154
III		Peptide ligand (ALA,LEU,PRO,ALA,TRP,ALA,ARG,PRO,ASP)	4j1v	C	R154
III		Peptide ligand (GLY,THR,MET,LYS,ARG,ASN)	5brm	B	R154
III		Peptide ligand (THR,MET,LYS,ARG)	5brm	C	R154
III		Peptide ligand (THR,MET,LYS,ARG,ASN)	5brm	D	R154

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Conservation information for LBS of MOB1A

Multiple alignments for Q9H8S9 in multiple species

LBS	AA sequence	# species	Species
A177	QLQEEAHLNTS	3	Homo sapiens, Mus musculus, Rattus norvegicus
A177	ELNLQTVLNTS	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
A177	AMELESYLNTS	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
A202	DRRELAPLQEL	3	Homo sapiens, Mus musculus, Rattus norvegicus
A202	RPADFGPLLEL	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
A202	DNKEYAPMQDL	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
A58	LNEWIAVNTVD	3	Homo sapiens, Mus musculus, Rattus norvegicus
A58	ENEWLAVHCVD	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
A58	LNEWIAMNTMD	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
A98	YEYHWADGTNI	3	Homo sapiens, Mus musculus, Rattus norvegicus
A98	YEYLWAFQKG-	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
A98	YEYYWQDDKIY	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
C79	TITEFCTEASC	3	Homo sapiens, Mus musculus, Rattus norvegicus
C79	SITEFCSPQTC	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
C79	TITEFCTAASC	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
C84	CTEASCPVMSA	3	Homo sapiens, Mus musculus, Rattus norvegicus
C84	CSPQTCPRMIA	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
C84	CTAASCPQMNA	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
D116	APKYIDYLMTW	3	Homo sapiens, Mus musculus, Rattus norvegicus
D116	APKYVECLMRW	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
D116	APDYINNLLDW	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
D127	VQDQLDDETLF	3	Homo sapiens, Mus musculus, Rattus norvegicus
D127	CQDQFDDESLF	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
D127	TQEKLDDKKLF	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
D168	YHQHFDSVMQL	3	Homo sapiens, Mus musculus, Rattus norvegicus
D168	YCHHFNEILEL	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
D168	YCSHFHVMVAM	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
D99	EYHWADGTNIK	3	Homo sapiens, Mus musculus, Rattus norvegicus
D99	EYLWAFQKG-Q	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
D99	EYYWQDDKIYT	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
E176	MQLQEEAHLNT	3	Homo sapiens, Mus musculus, Rattus norvegicus
E176	LELNLQTVLNT	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
E176	VAMELESYLNT	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
E200	LIDRRELAPLQ	3	Homo sapiens, Mus musculus, Rattus norvegicus
E200	LLRPADFGPLL	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
E200	LMDNKEYAPMQ	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
E206	LAPLQELIEKL	3	Homo sapiens, Mus musculus, Rattus norvegicus
E206	FGPLLELVMEL	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
E206	YAPMQDLVDSM	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
E94	AGPRYEYHWAD	3	Homo sapiens, Mus musculus, Rattus norvegicus
E94	ATNEYEYLWAF	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
E94	AGPSYEYYWQD	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
F132	DDETLFPSKIG	3	Homo sapiens, Mus musculus, Rattus norvegicus
F132	DDESLFPSKVT	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
F132	DDKKLFPTEIG	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
F140	KIGVPFPKNFM	3	Homo sapiens, Mus musculus, Rattus norvegicus
F140	KVTGTFPEGFI	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
F140	EIGVEFPKNFR	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
F167	IYHQHFDSVMQ	3	Homo sapiens, Mus musculus, Rattus norvegicus
F167	IYCHHFNEILE	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
F167	IYCSHFHVMVA	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
F65	NTVDFFNQINM	3	Homo sapiens, Mus musculus, Rattus norvegicus
F65	HCVDFYNQINM	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
F65	NTMDFYTQINM	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
H161	FRVYAHIYHQH	3	Homo sapiens, Mus musculus, Rattus norvegicus
H161	FRVYAHIYCHH	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
H161	FRIYAHIYCSH	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
H164	YAHIYHQHFDS	3	Homo sapiens, Mus musculus, Rattus norvegicus
H164	YAHIYCHHFNE	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
H164	YAHIYCSHFHV	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
H166	HIYHQHFDSVM	3	Homo sapiens, Mus musculus, Rattus norvegicus
H166	HIYCHHFNEIL	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
H166	HIYCSHFHVMV	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
H178	LQEEAHLNTSF	3	Homo sapiens, Mus musculus, Rattus norvegicus
H178	LNLQTVLNTSF	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
H178	MELESYLNTSF	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
H96	PRYEYHWADGT	3	Homo sapiens, Mus musculus, Rattus norvegicus
H96	NEYEYLWAFQK	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
H96	PSYEYYWQDDK	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
I103	ADGTNIKKPIK	3	Homo sapiens, Mus musculus, Rattus norvegicus
I103	AFQKG-QPPVS	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
I103	QDDKIYTKPTR	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
I115	SAPKYIDYLMT	3	Homo sapiens, Mus musculus, Rattus norvegicus
I115	SAPKYVECLMR	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
I115	SAPDYINNLLD	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
I136	LFPSKIGVPFP	3	Homo sapiens, Mus musculus, Rattus norvegicus
I136	LFPSKVTGTFP	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
I136	LFPTEIGVEFP	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
K104	DGTNIKKPIKC	3	Homo sapiens, Mus musculus, Rattus norvegicus
K104	FQKG-QPPVSV	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
K104	DDKIYTKPTRM	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
K105	GTNIKKPIKCS	3	Homo sapiens, Mus musculus, Rattus norvegicus
K105	QKG-QPPVSVS	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
K105	DKIYTKPTRMS	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
K113	KCSAPKYIDYL	3	Homo sapiens, Mus musculus, Rattus norvegicus
K113	SVSAPKYVECL	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
K113	RMSAPDYINNL	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
K135	TLFPSKIGVPF	3	Homo sapiens, Mus musculus, Rattus norvegicus
K135	SLFPSKVTGTF	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
K135	KLFPTEIGVEF	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
K153	AKTILKRLFRV	3	Homo sapiens, Mus musculus, Rattus norvegicus
K153	IQPILRRLFRV	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
K153	IQQIFRRLFRI	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
K184	LNTSFKHFIFF	3	Homo sapiens, Mus musculus, Rattus norvegicus
K184	LNTSFRHFCLF	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
K184	LNTSFKHFVFF	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
K210	QELIEKLGSKD	3	Homo sapiens, Mus musculus, Rattus norvegicus
K210	LELVMELR--D	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
K210	QDLVDSMV---	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
L126	WVQDQLDDETL	3	Homo sapiens, Mus musculus, Rattus norvegicus
L126	WCQDQFDDESL	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
L126	WTQEKLDDKKL	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
L204	RELAPLQELIE	3	Homo sapiens, Mus musculus, Rattus norvegicus
L204	ADFGPLLELVM	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
L204	KEYAPMQDLVD	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
L207	APLQELIEKLG	3	Homo sapiens, Mus musculus, Rattus norvegicus
L207	GPLLELVMELR	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
L207	APMQDLVDSMV	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
L36	HAEATLGS-GN	3	Homo sapiens, Mus musculus, Rattus norvegicus
L36	IVEMTLGSEGV	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
L36	YAEATLGS-GS	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
M119	YIDYLMTWVQD	3	Homo sapiens, Mus musculus, Rattus norvegicus
M119	YVECLMRWCQD	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
M119	YINNLLDWTQE	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
M171	HFDSVMQLQEE	3	Homo sapiens, Mus musculus, Rattus norvegicus
M171	HFNEILELNLQ	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
M171	HFHVMVAMELE	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
M70	FNQINMLYGTI	3	Homo sapiens, Mus musculus, Rattus norvegicus
M70	YNQINMLYGSI	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
M70	YTQINMLYGTI	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N180	EEAHLNTSFKH	3	Homo sapiens, Mus musculus, Rattus norvegicus
N180	LQTVLNTSFRH	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N180	LESYLNTSFKH	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N66	TVDFFNQINML	3	Homo sapiens, Mus musculus, Rattus norvegicus
N66	CVDFYNQINML	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N66	TMDFYTQINML	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N69	FFNQINMLYGT	3	Homo sapiens, Mus musculus, Rattus norvegicus
N69	FYNQINMLYGS	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N69	FYTQINMLYGT	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P106	TNIKKPIKCSA	3	Homo sapiens, Mus musculus, Rattus norvegicus
P106	KG-QPPVSVSA	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P106	KIYTKPTRMSA	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P133	DETLFPSKIGV	3	Homo sapiens, Mus musculus, Rattus norvegicus
P133	DESLFPSKVTG	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P133	DKKLFPTEIGV	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P91	VMSAGPRYEYH	3	Homo sapiens, Mus musculus, Rattus norvegicus
P91	RMIATNEYEYL	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P91	QMNAGPSYEYY	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q123	LMTWVQDQLDD	3	Homo sapiens, Mus musculus, Rattus norvegicus
Q123	LMRWCQDQFDD	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q123	LLDWTQEKLDD	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R154	KTILKRLFRVY	3	Homo sapiens, Mus musculus, Rattus norvegicus
R154	QPILRRLFRVY	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
R154	QQIFRRLFRIY	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R157	LKRLFRVYAHI	3	Homo sapiens, Mus musculus, Rattus norvegicus
R157	LRRLFRVYAHI	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
R157	FRRLFRIYAHI	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R199	NLIDRRELAPL	3	Homo sapiens, Mus musculus, Rattus norvegicus
R199	ELLRPADFGPL	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
R199	GLMDNKEYAPM	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R92	MSAGPRYEYHW	3	Homo sapiens, Mus musculus, Rattus norvegicus
R92	MIATNEYEYLW	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
R92	MNAGPSYEYYW	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
S134	ETLFPSKIGVP	3	Homo sapiens, Mus musculus, Rattus norvegicus
S134	ESLFPSKVTGT	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
S134	KKLFPTEIGVE	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
T181	EAHLNTSFKHF	3	Homo sapiens, Mus musculus, Rattus norvegicus
T181	QTVLNTSFRHF	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
T181	ESYLNTSFKHF	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
T76	LYGTITEFCTE	3	Homo sapiens, Mus musculus, Rattus norvegicus
T76	LYGSITEFCSP	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
T76	LYGTITEFCTA	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
V59	NEWIAVNTVDF	3	Homo sapiens, Mus musculus, Rattus norvegicus
V59	NEWLAVHCVDF	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
V59	NEWIAMNTMDF	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
V62	IAVNTVDFFNQ	3	Homo sapiens, Mus musculus, Rattus norvegicus
V62	LAVHCVDFYNQ	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
V62	IAMNTMDFYTQ	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
W97	RYEYHWADGTN	3	Homo sapiens, Mus musculus, Rattus norvegicus
W97	EYEYLWAFQKG	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
W97	SYEYYWQDDKI	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y114	CSAPKYIDYLM	3	Homo sapiens, Mus musculus, Rattus norvegicus
Y114	VSAPKYVECLM	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y114	MSAPDYINNLL	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y163	VYAHIYHQHFD	3	Homo sapiens, Mus musculus, Rattus norvegicus
Y163	VYAHIYCHHFN	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y163	IYAHIYCSHFH	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y72	QINMLYGTITE	4	Homo sapiens, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Mus musculus, Rattus norvegicus
Y72	QINMLYGSITE	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y93	SAGPRYEYHWA	3	Homo sapiens, Mus musculus, Rattus norvegicus
Y93	IATNEYEYLWA	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y93	NAGPSYEYYWQ	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y95	GPRYEYHWADG	3	Homo sapiens, Mus musculus, Rattus norvegicus
Y95	TNEYEYLWAFQ	1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y95	GPSYEYYWQDD	1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)